- Reaction score
- 742
Spironolactone causes accumulation of belly fat, and worse... visceral fat around your internal organs. Estradiol levels do affect your metabolism. If your free estradiol natural levels are in the mid-normal to high- normal range for a biological female, supplemental estradiol wouldn't likely do you much good but if low , then it may help. Being a bio female, you have to keep in mind the possibility of elevated breast cancer risk from too high estrogen levels, but it's been demonstrated now that bio-identical progesterone helps to reduce or even eliminate that cancer risk because it acts to moderate how the free estradiol in your body gets used / bound to estrogen receptors. Progesterone also reduces the risk of DVT/clots due to too much estradiol getting converted into estrone sulfate which is the actual culprit in causing clots.
P.S. Diane is poison and ought to be banned.
In the MtF Trans discussion forum on Facebook that I frequent... there seems to be a general consensus that I.M. Injected estradiol and progesterone do not contribute to weight gain outside of (in MtFs) slowing metabolish down from male levels, and not feeling much energy due to the now having severe lack of testosterone. In fact some trans women are prescribed small doses of testosterone supplements to bring their energy back up, and the progesterone helps to inhibit DHT to battle the hairloss problem because some free testosterone actually helps hair grow... but to want to keep it from turning into DHT. It's all an intricate and intertwined complex mess of endocrine system hacking and tinkering...
Why is Diane poison?
Would it be worth me low dosing spironolactone ?
What's the best drug to battle feminizing effects?
Why wear purple when pink would bring out your eyes more?