so are they any companies that will make a product minoxidil like this you report with antiinflamantory diclofenac and tea tree oil. what would be super awesome squeegee is to see the hydroxylase effect of this boosted minoxidil. i believe tea tree oil will even out or cancel completely the aging. we then afte a year of dermarolling will have a topical of each night with no aged skin sides to keep what we grew from wounds.
sounds like a plan.
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or if we could make a topical in nanosolution to release it self slow and apply it once a week and contain this minoxidil,cb,emu oil,keto,nitric oxide, i am just dreaming.
Remember that study?
At least we had the balls to start something totally new!, we can still tweak or derma rolling regimen as we go. We can still brew our topical anti-inflammatory and do intervals.. nano solution could be an option as well. Use the derma-roller for deep absorption. 2 weeks on the anti-inflammatory/2 weeks on the micro-needling.
http://www.ijtrichology.com/article...;issue=2;spage=73;epage=76;aulast=Nirmal#ref6
Background: Mild perifollicular inflammation is seen in both androgenetic alopecia (Androgenetic Alopecia) cases and normal controls, whereas moderate or dense inflammation with concentric layers of collagen, is seen in Androgenetic Alopecia cases but only in very few normal controls, and may lessen the response to topical minoxidil. Moderate or dense lymphocytic inflammation and perifollicular fibrosis have poor hair growth following transplantation.
Aim: The purpose of the study is to evaluate the perifollicular lymphocytic inflammation and fibrosis in Androgenetic Alopecia patients during follicular unit hair transplantation (FUT) and its comparison in normal controls.
Materials and Methods: A total of 21 male patients with Androgenetic Alopecia and 7 matched controls participated in the study. Histopathological analysis of biopsy specimens from donor strip of patients during the hair transplantation and two 4 mm punch biopsies on controls were performed. Morphometric analysis was performed and perifollicular fibrosis was scored based on the width of the condensed collagen at the lower infundibulum and isthmus from 0 to 3. Perifollicular infiltrate was also scored 0-3 and a total score of 3 or more out of 6 was considered significant.
Results: Nearly 76% of Androgenetic Alopecia patients had perifollicular fibrosis more than 50 μm at ×200 magnification. Almost 33.33% patients had moderate/dense perifollicular lymphocytic infiltrate whereas none of the controls had it. Total score in Androgenetic Alopecia cases was significantly higher than controls (
P = 0.012) using Chi-square test. Out of 21 patients, 13 had a score of 3 or more and were followed-up with monthly treatment with intralesional steroids using a dermaroller.
Conclusion: Histopathological evaluation of the donor area is a must during hair transplantation to evaluate the extent of perifollicular inflammation and achieve better results by following it up with treatment directed to decrease the inflammation.
Inflammation is the b**ch!
http://www.hairlosstalk.com/interac...8-Fibrosis-Inflammation-amp-Androgen-Alopecia
Figure 5: Post-transplant intralesional treatment with dermaroller and steroids.
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Persistent is the key also.. that guy was using a 1.5mm here and there. Probably not even heavy an deep.. and got results from it. True pioneer back in the days.
http://www.hairlosstalk.com/interact/showthread.php/25910-Skin-Needling/page24
Wish I had better documented my journey. It's so illuminating rather than depending on memory alone. Anyhow, I managed to dig up a few photos. I wasn't always one normally inclined to take photographs.
Photo on left: April 2006: using finasteride orally and topically, minoxidil, retin-a... losing hair rapidly at the temples. Just prior to starting needling and dropping finasteride.
Photo on right: June 2008: two years later ... been off of finasteride for two years, using needling, minoxidil with most of the topicals mentioned in my posts. Hairline in the middle grew down a half an inch, right temple grew in fully, left lagging behind.
Photo on left: April 2006: using finasteride, minoxidil, retin-a. Just prior to starting needling and dropping finasteride.
Photo on right: August 2009 - three years later... been off of finasteride for three years, using just needling, minoxidil with most of the topicals mentioned in my posts.
Both temples are fully grown with left slightly lagging, nice thick vellus defining the hairline. Just prior to my botched experiment with topical DIM. was the true pioneer of the 1.5mm. He probably wasn't going deep and heavy as well.. just constant stabbing here and there..
