I think it's possible, because at the end of the day the goal is to target scalp DHT specifically, and when you take it systemically it doesn't target the scalp. So in theory it would probably create some progress. Probably wouldn't really increases the side effect profile if you're already taking it orally. However, finasteride raises T a little bit, and if you're applying it to the hairline it could potentially worsen it. Ideally, you'd probably be better off with RU on the hairline, and finasteride/dutasteride on the crown.