No Effective Treatment In 20 Years?

[Ryko]

There is microneedling, I don't know why people don't mention it. It's proven to be effective with or without minoxidil, it takes 5 minutes a week and your scalp also feels healthier.

Edit: Don't dislike this cause you're an angry bald, microneedling works.

 

[Kagaho]

How did you get access to follica? Are you doing a trial with them?

Nah. I watched Puretech latest podcast. Follica raised almost 14 million last year and their phase 3 is expected to commence soon.

I do have to say Daphne Zohar didnt want to talk about details, but thats common business with them.

Im doing minoxidil + dermapen and ocassionally dermarolling since november 2017. It has been effective for me. Follica 1st iteration wont differ substantially, maybe the depth of the needles or some other compound but i dont think that will impact results dramatically.

They are also doing preclinical for a propretary drug, but thats really far from the market at this point.

 

[Kagaho]

haven't they said they are going to do another phase 2 trial for optimization or some sh*t? realistically how far and especially how reliable are they?

They are doing an optimization trial for one of the devices.

About how far they are, i think its the closest to the market. They are pursuing FDA Clearance because its a medical device so they have it much easier.

They have a pretty good team and are backed by a prestigious biotech.

 

[Kagaho]

why is there no picture of results? why is there not even open studies that describe increase in hair count etc etc? they have basically nothing, seems very suspicious

I think its really easy to emulate their treatment with current disruption tools. If you read their latest patent you will find a dermapen like device, with the needles and everything. Thats probably the tool they are using on the optimization trial.

If you read the numbers of the chinese study using a dermapen, those correlates with Follica disclosed data. And the indian one by Dhurat is also inspired by Cots science.

What im trying to say is, they will have a hard time selling their 1st stuff. That could explain something

 

[Kagaho]

I don't really care. they don't have a SINGLE study published at all. nothing. it seems to like ultra stereotype of a fraud company, brilliant marketing, brand new responsive website, the mobile app is ready but no product, that scream fraudster so loud. they have done 3 phase studies, where are the results? I can't wrap my head around this. most companies post their results with hair count etc etc etc. but this one... same with histogen, if their results where that great and the needling neogenesis things actually worked, they wouldn't shy away from doing that

Their results were disclosed: 25 hairs per cm2 were their best. They try to increase the numbers by using lithium gluconate (WNT act) but failed.

Their science is behind the succesful dermarolling + minoxidil studies and tons of anecdotal reports. I still trust them, but like you im tired of their secretism.

I think they will start pivotal this year. Maybe im too naive though

 

[Kagaho]

source of this?

@petersonKj will try to answer later. I think you should research a little more by your own. Its not fair to put Follica and Histogen in the same bag.

Those numbers were mentioned on their 2017 presentation

 

[Kagaho]

About Histogen, yeah those guys are very dubious. Their pics were crap and mostly women

 

[soull]

The most interesting thing I see in Folica is the mode ofapplication that can give us as time, depth etc... I have doubtsthat it can come out in the market sometime in the year 2020

 

[soull]

its all a joke nothing more to say. finasteride or shave for the next years

OK, so let's not go back for many years, right?

 

[soull]

It's over beyond hope now.

It's either we take Finasteride or Dutasteride (which both have dangerous side effects, not guaranteed to work, sometimes make hair even much worse), or go bald and accept that we'll never have a love life, society will never accept us and we'll die alone and miserable because of some sensitive follicles on top of our heads and bad luck.

Our lives are worthless.

His life is really worthless, it's not because of his hair, but hismind. Please do not write your cries on this forum and go to aprofessional who treats your mind. Since you are convincedthat nothing will come in decades please do not publish, doesnot help anyone and less to you. Thank you

 

[Caillou]

His life is really worthless, it's not because of his hair, but hismind. Please do not write your cries on this forum and go to aprofessional who treats your mind. Since you are convincedthat nothing will come in decades please do not publish, doesnot help anyone and less to you. Thank you

f*** off you are mentally retarded thats why you fail at those things

If hair loss is not so bad in your opinions and my mindset is the problem, then why are you browsing this forum all day?

 

[Caillou]

if your life is really that horrible why haven't you killed yourself?

I'm coping by the fact that i'm not the only one here whose life is destroyed by this curse.

 

[soull]

If hair loss is not so bad in your opinions and my mindset is the problem, then why are you browsing this forum all day?

First I'm not all day, I just watch and hope there is somethingnew. I Don't come to mourn like you, it's the differencebetween a sane person and a madman like you.

 

[Caillou]

First I'm not all day, I just watch and hope there is somethingnew. I Don't come to mourn like you, it's the differencebetween a sane person and a madman like you.

Whatever helps you to sleep at night man.

 

[soull]

Whatever helps you to sleep at night man.

Do us all a favor and stop publishing and also those who donot expect anything in decades. An administrator should cleanthe spam

 

[Kagaho]

My opinion (can be totally wrong) about the current situation of Follica:

I think they are in a very particular situation. They have something that works but it is not a very profitable product because every average Joe can buy cheap old minoxidil and a dermaroller or dermastamp and have similar results. So very few people will be willing to spend thousands of dollars for in office sessions and the fancy at home device.

This is why they are investing good money doing preclinical testing for a compound that not only enhace their protocol but also something to cash in. Something that can substantially differenciate them from the cheaper option in the long run.

The more I think about the more Im convinced they will only start pivotal when they finish preclinical for this drug.

The good news is my speculation can be a total nonsense because Follica going phase 3 this year was mentioned again on their podcast (march 6) as one of the upcoming events of Puretech affiliates.

 

[Sam1]

Histogen and Samumed are suppose to release in 2020

 

[Mandar kumthekar]

Cure means what? Hairloss is result of 200 genes making you bald on daily basis. How would there be a cure to fight 200 genes ? I think hairloss and baldness cure will remain elusive for many decades to come.

 

[byebyehair]

I am coming soon. Hold on to what you have, so that no one will take your crown.
Revelation 3:11 | NIV |

The bible was also promissing a baldness cure back in year 0...

 

[kiwipilu]

Cure means what? Hairloss is result of 200 genes making you bald on daily basis. How would there be a cure to fight 200 genes ? I think hairloss and baldness cure will remain elusive for many decades to come.

what genes? I agree hairloss a huge labyrinth but the irony is that at the end of the day, it does not look that "complicated" to me. scientists just need to find what could trigger unlimited regrowth(Or call it scalp hypertrichosis if you want) for any kind of hairloss. they have to find the right pathway, to send the right message to the hair follicle. maybe a random drug could trigger this (like a very potent minoxidil) but it's yet to be discovered (does it exist already? **** knows)! Anyway. for me ,applying a topical daily to regrow a full head of hairs and maintaining forever ? I'd call it a cure. ; )