Old Kitchen Sink Approach- Dont Just Rely On Seti Alone....

proscar2

Established Member
My Regimen
Reaction score
111
http://hairlosshelp.net/forums/messageview.cfm?catid=10&threadid=116960

old hellhouser post - as you can see...... quite a rounded approach- DO NOT RELY ON JUST SETI....


I am going to be summarizing/comparing the following (5) protocols.... of which ALL are basically working off the SAME premise of the Dr. Costsorelis/Follica patent(s) ..... although each has their own minor tweaks.....thus the goal is too be collaborative....with further added tweaks for the ultimate "Best Practice" protocol. "For the record, I've posted essentially Swiss's protocol almost a year ago (Dec. 8th, 2014) and it went unnoticed;


This what happens to your scalp and follicles when you've got hair loss:

Upregulation of the following:
Dihydrotestosterone
DKK1
Arachidonic Acid
PGD2

Downregulation of the following:
PGE2
CD200 Progenitor Cells
CD34 Progenitor Cells

To combat this, you need the following will solve these issues:

DHT - Finasteride, Dutasteride, RU58841, CB-03-01
DKK1 - unknown
Arachidonic Acid - Nizoral (but nizoral also inhbits PGE2)
PGD2 - Setipiprant, OC459
PGE2 - Minoxidil, Latanoprost, Sulphasalazine, Sunburns (UVB)
CD200 - Lithium Chloride
CD34 - Stemoxydine

Wounding should also be done with this approach as it releases a whole host of positive factors."
 

whatevr

Senior Member
My Regimen
Reaction score
3,659
I would love for this to be the answer. However, this is what Swiss and everyone at Pioneering Hair Growth was doing and pretty much no one saw regrowth. Unlike most of the people here, they were getting pure stuff and using a good vehicle too.

As for DKK1 - https://www.hairlosstalk.com/interact/threads/dkk1-inhibition-with-l-threonate.77749/

f*** that. Regrowth is a whole different ball game. I would KILL someone for maintenance without side effects right now.

RU - awful brain fog
Finasteride - Gyno, brain fog, still hair loss
Estrogen - slight regrowth, gyno

I can't maintain with anything. If seti allowed me to keep my hair, I could even get a transplant and call it a day. PERFECT is the enemy of GOOD. You first need to stabilize your hair and secure against further hair loss. PGD2 HAS to go down for that to happen. The issue is the price. There has to be a good topical vehicle where one can get away with ~250 mg a day. 2 grams a day is almost a quarter of my f*****g paycheck. I can't be paying that.
 

Junior2491

Member
My Regimen
Reaction score
42
I would love for this to be the answer. However, this is what Swiss and everyone at Pioneering Hair Growth was doing and pretty much no one saw regrowth. Unlike most of the people here, they were getting pure stuff and using a good vehicle too.



As for DKK1 - https://www.hairlosstalk.com/interact/threads/dkk1-inhibition-with-l-threonate.77749/

didn't West get some regrowth? Also some other members claimed positive results from Seti and Castor Oil. At the very least doesn't Seti at least maintain what you have?
 

Alex Contee

Established Member
My Regimen
Reaction score
223
didn't West get some regrowth? Also some other members claimed positive results from Seti and Castor Oil. At the very least doesn't Seti at least maintain what you have?
West clearly has some regrowth. If it is cosmetically acceptable growth is debatable but he is doing an incredible job with his updates and information. Thank goodness for him.

The previously mentioned forum guys were not using high dosages of oral Seti to the best of my knowledge. West however, is not most of the rest of the protocol in the OP. He recently reintroduced wounding and PGE2.

Seti might be something great. We will know for when the trial ends. However, it is not reasonable to purchase Seti you can digest outside of a group buy that includes legit testing. I won't knowingly put something with less than 99% pure on my scalp as a topical. I am sure as heck not going to digest something that could have 3-5% unknown impurities. West is great and this looks promising but I implore people to be safe.
 

sunchyme1

Senior Member
My Regimen
Reaction score
6,988
f*** that. Regrowth is a whole different ball game. I would KILL someone for maintenance without side effects right now.

RU - awful brain fog
Finasteride - Gyno, brain fog, still hair loss
Estrogen - slight regrowth, gyno

I can't maintain with anything. If seti allowed me to keep my hair, I could even get a transplant and call it a day. PERFECT is the enemy of GOOD. You first need to stabilize your hair and secure against further hair loss. PGD2 HAS to go down for that to happen. The issue is the price. There has to be a good topical vehicle where one can get away with ~250 mg a day. 2 grams a day is almost a quarter of my f*****g paycheck. I can't be paying that.

if hair loss drugs werent a big enough joke as it is, it would be even more hilarious if the ONE f*****g treatment that did work and didnt give you sides was the only one you couldnt afford lol
 

Afro_Vacancy

Senior Member
My Regimen
Reaction score
11,939
if hair loss drugs werent a big enough joke as it is, it would be even more hilarious if the ONE f*****g treatment that did work and didnt give you sides was the only one you couldnt afford lol


Ummmm ... it's called the FUE transplant :)
 

Alex Contee

Established Member
My Regimen
Reaction score
223
not a treatment for heavy balders like me and whatevr

we need to stop this f****r before going down that road mate
I am in the same boat. I am Norwood 2.5 and I have been losing hair for a little over a decade now. I have maintained fairly well but my hair sucks and I am unfortunatly pretty thin all over. Multiple hair transplant surgeons have told me I am either not a candidate for any transplant or at least not a candidate for FUE.
 

proscar2

Established Member
My Regimen
Reaction score
111
did anyone manage to go through the 20+ pages of the link ? i didn't have time
 

kiwipilu

Experienced Member
My Regimen
Reaction score
1,052
If I remember well , Ironically taking care of dkk1 alone would be it (according to studies)… But we have nothing substantial we can put our hands on or complete / detailed sudies
 

Alex Contee

Established Member
My Regimen
Reaction score
223
f*** that. Regrowth is a whole different ball game. I would KILL someone for maintenance without side effects right now.

RU - awful brain fog
Finasteride - Gyno, brain fog, still hair loss
Estrogen - slight regrowth, gyno

I can't maintain with anything. If seti allowed me to keep my hair, I could even get a transplant and call it a day. PERFECT is the enemy of GOOD. You first need to stabilize your hair and secure against further hair loss. PGD2 HAS to go down for that to happen. The issue is the price. There has to be a good topical vehicle where one can get away with ~250 mg a day. 2 grams a day is almost a quarter of my f*****g paycheck. I can't be paying that.

Fighting the side effects of meds with other meds is always a losing battle and I can't wait for a day when we can say goodbye to treatments like finasteride and RU. With that said, I have had some success combating brain fog with supplements that increase GABA. Yoga, exercise, and my inversion table help a lot too. Still searching for a good way to increase allopregnanolone. 5a-DHP is promising and made me feel close to normal again but I stopped taking it after some studies linked it to an increase chance of cancer. Hopefully more research is done.
 

Georgie

Senior Member
My Regimen
Reaction score
2,721
http://hairlosshelp.net/forums/messageview.cfm?catid=10&threadid=116960

old hellhouser post - as you can see...... quite a rounded approach- DO NOT RELY ON JUST SETI....


I am going to be summarizing/comparing the following (5) protocols.... of which ALL are basically working off the SAME premise of the Dr. Costsorelis/Follica patent(s) ..... although each has their own minor tweaks.....thus the goal is too be collaborative....with further added tweaks for the ultimate "Best Practice" protocol. "For the record, I've posted essentially Swiss's protocol almost a year ago (Dec. 8th, 2014) and it went unnoticed;


This what happens to your scalp and follicles when you've got hair loss:

Upregulation of the following:
Dihydrotestosterone
DKK1
Arachidonic Acid
PGD2

Downregulation of the following:
PGE2
CD200 Progenitor Cells
CD34 Progenitor Cells

To combat this, you need the following will solve these issues:

DHT - Finasteride, Dutasteride, RU58841, CB-03-01
DKK1 - unknown
Arachidonic Acid - Nizoral (but nizoral also inhbits PGE2)
PGD2 - Setipiprant, OC459
PGE2 - Minoxidil, Latanoprost, Sulphasalazine, Sunburns (UVB)
CD200 - Lithium Chloride
CD34 - Stemoxydine

Wounding should also be done with this approach as it releases a whole host of positive factors."
What about VPA?

Also do we actually know anyone who’s on all this stuff? Sulfa appaently is useless topically and I can’t imagine that anyone is taking it orally without have autoimmune diseases.

I’d like to know more about the DKK1 inhibitor though
 

omega

Member
My Regimen
Reaction score
13
Sulfa appaently is useless topically and I can’t imagine that anyone is taking it orally without have autoimmune diseases.

Why useless topically?

Should be used with penetration enhancers
such as ethanol, dmso or dmi, Propylene Glycol, Purified Water, and Ethyl Alcohol
 

buckthorn

Banned
My Regimen
Reaction score
5,209
http://hairlosshelp.net/forums/messageview.cfm?catid=10&threadid=116960

old hellhouser post - as you can see...... quite a rounded approach- DO NOT RELY ON JUST SETI....


I am going to be summarizing/comparing the following (5) protocols.... of which ALL are basically working off the SAME premise of the Dr. Costsorelis/Follica patent(s) ..... although each has their own minor tweaks.....thus the goal is too be collaborative....with further added tweaks for the ultimate "Best Practice" protocol. "For the record, I've posted essentially Swiss's protocol almost a year ago (Dec. 8th, 2014) and it went unnoticed;


This what happens to your scalp and follicles when you've got hair loss:

Upregulation of the following:
Dihydrotestosterone
DKK1
Arachidonic Acid
PGD2

Downregulation of the following:
PGE2
CD200 Progenitor Cells
CD34 Progenitor Cells

To combat this, you need the following will solve these issues:

DHT - Finasteride, Dutasteride, RU58841, CB-03-01
DKK1 - unknown
Arachidonic Acid - Nizoral (but nizoral also inhbits PGE2)
PGD2 - Setipiprant, OC459
PGE2 - Minoxidil, Latanoprost, Sulphasalazine, Sunburns (UVB)
CD200 - Lithium Chloride
CD34 - Stemoxydine

Wounding should also be done with this approach as it releases a whole host of positive factors."

I don't think ANYONE has ever relied on seti for ANYTHING. pure garbage.
 
Top