PDRN, an unknown powerhouse for androgenic alopecia

[FollicleGuardian]

If true, EXTREMELY impressive.

I am confused. I read it. They provide no background on PDRN, as if it has been used previously and its effect has been established. This is F** impressive. Looking at the pictures. You can tell the health of the scalp has changed dramatically. It went looking like my thinning area to my donor area. This is the exact same thing in my microscopic pictures. If this is true, @FollicleGuardian you are a follicle guardian.

These are typical in this literature.

These numbers are very high. I wish they evaluated them in #hairs/cm2. Keep in mind though women, like mice, usually respond better to treatments. (histogen, prp, follica, you name it).

Yes no background at all. Very weird haha.

Yes I agree, the scalp look much more healthy!

 

[pegasus2]

Ok great find and thread but not a single post saying If this really Works.

Rub it on your head and find out

 

[Will Be an Egg in 5 years]

Rub it on your head and find out

I'd gladly do it and post the results. There's no sense in doing it and keeping to myself.

 

[Will Be an Egg in 5 years]

The study shows hair count increase of almost 20% compared to baseline, what the f**k.

Holy sh*t

 

[pegasus2]

Polydeoxyribonucleotide Activates Mitochondrial Biogenesis but Reduces MMP-1 Activity and Melanin Biosynthesis in Cultured Skin Cells - PubMed

The regulation of mitochondrial biogenesis, melanogenesis, and connective tissue proteins is critical for homeostasis and aging skin cells. We examined the biological effects of polydeoxyribonucleotide (PDRN) on mitochondrial biogenesis, melanogenesis, and connective tissue proteins in vitro. In...

pubmed.ncbi.nlm.nih.gov

Polydeoxyribonucleotide Activates Mitochondrial Biogenesis but Reduces MMP-1 Activity and Melanin Biosynthesis in Cultured Skin Cells​

Decreases melanin it seems. Won't this make your hair grey?

As posted in the other thread it does the opposite http://www.jkslms.or.kr/journal/view.html?uid=94&vmd=Full

 

[Zon Ama]

I am not into all the scientific theories of the treatment. What could be the expected side effects of this? Are there any?

 

[Zon Ama]

None

Seems to be too good to be true tbh, isnt it?
Somehow I always associate risk of cancer when I read about WNT.

 

[BetaBoy]

Wouldn’t it be easier to get and use something like BPC-157 if promotion of healing is the only important factor?

 

[FollicleGuardian]

How do you get this stuff without prescription?
Wouldnt it get cought in the customs?

It’s OTC in the EU.

 

[FollicleGuardian]

Wouldn’t it be easier to get and use something like BPC-157 if promotion of healing is the only important factor?

But it’s not the only factor.

 

[FollicleGuardian]

Seems to be too good to be true tbh, isnt it?
Somehow I always associate risk of cancer when I read about WNT.

WNT agonism is not it’s main target. It’s not powerful enough to cause cancer because of WNT signalling.

 

[LouisSarkozy]

s

WNT agonism is not it’s main target. It’s not powerful enough to cause cancer because of WNT signalling.

sorry to bother you again but do you know if it has an effect on tgf b1 inhibition?

 

[charcoal]

Can someone tell is this the same as Placentex:

Placentrex Gel: View Uses, Side Effects, Price and Substitutes | 1mg

Placentrex Gel is used in the treatment of Chronic non-healing wounds. View Placentrex Gel (tube of 20.0 gm Gel) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.com

www.1mg.com

It's available in vials too. Its description seems similar and it's dirt cheap in India.

 

[FollicleGuardian]

s

sorry to bother you again but do you know if it has an effect on tgf b1 inhibition?

I’m not sure

 

[FollicleGuardian]

Can someone tell is this the same as Placentex:

Placentrex Gel: View Uses, Side Effects, Price and Substitutes | 1mg

Placentrex Gel is used in the treatment of Chronic non-healing wounds. View Placentrex Gel (tube of 20.0 gm Gel) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.com

www.1mg.com

It's available in vials too. Its description seems similar and it's dirt cheap in India.

Placentrex is human derived placenta
Placentex is salmon dna derived

 

[Seuxin]

Anyone know the "brand/name" in EU ?

 

[FollicleGuardian]

Anyone know the "brand/name" in EU ?

Placentex pomata

 

[thetdog666]

Placentex pomata

What protocol are you going to use for the cream? Daily?

 

[Zon Ama]

Won’t be a problem.

How can you say that bro?
I mean there are no studies about the long-term use of this stuff on your head.
Dont get me wrong, I appreciate all your findings and posts about Kintor, PDRN, etc. but people should be cautious when using stuff like this

 

[Gegen]

How can you say that bro?
I mean there are no studies about the long-term use of this stuff on your head.
Dont get me wrong, I appreciate all your findings and posts about Kintor, PDRN, etc. but people should be cautious when using stuff like this

That's polynucleotide from salmon sperm, not some weird all-synthetized molecule. No way it will do anything more powerful than tiny irritations or things like this ( if there is side effects ).
But for Kintor I'd be more cautious though.