From what I understand when they use it on burn victims they apply it as a paste over the damaged areas.I really don’t know how I feel about taking my scalp off and putting a new one on...
So I don't think you would have to be scalped in order for this to take hold but there would probably have to be damaging done. So maybe something like a vigourous micro-needling session or a few dermal layers peeled off with a chemical. Speculation only of course