Prolactin created during orgasm

[ripple-effect]

Masturbation induces a spike in prolactin levels that can last at least a couple of hours. There is also evidence to suggest that prolactin is a hair growth inhibitor. If there's any connection between masturbation and hair loss, prolactin could be the culprit. Read the two abstracts below.

Regards,
TAGOHL

Orgasm-induced prolactin secretion: feedback control of sexual drive?

Kruger TH, Haake P, Hartmann U, Schedlowski M, Exton MS.
Department of Medical Psychology, University of Essen, 45122 Essen, Germany.

Recent studies from our laboratory have investigated the hormonal response to various forms of sexual stimulation, including film, masturbation, and coitus in both men and women. This series of studies clearly demonstrated that plasma prolactin (PRL) concentrations are substantially increased for over 1h following orgasm (masturbation and coitus conditions) in both men and women, but unchanged following sexual arousal without orgasm. Here we discuss evidence suggesting that the PRL response to orgasm may play an important role in the control of acute sexual arousal following orgasm. Supporting this position, chronic elevations of PRL (hyperprolactinemia) produce pronounced reductions in animal sexual activity, and significant reduction of libido and gonadal function in both men and women. These data suggest that PRL may represent a peripheral regulatory factor for reproductive function, and/or a feedback mechanism that signals CNS centres controlling sexual arousal and behaviour. Thus, we propose a theoretical model of the role of PRL as a neuroendocrine reproductive reflex.

PMID: 11835982 [PubMed - indexed for MEDLINE]


Human scalp hair follicles are both a target and a source of prolactin, which serves as an autocrine and/or paracrine promoter of apoptosis-driven hair follicle regression.

Foitzik K, Krause K, Conrad F, Nakamura M, Funk W, Paus R.
Department of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany. kfoitzik@yahoo.com

The prototypic pituitary hormone prolactin (PRL) exerts a wide variety of bioregulatory effects in mammals and is also found in extrapituitary sites, including murine skin. Here, we show by reverse transcriptase-polymerase chain reaction and immunohistology that, contrary to a previous report, human skin and normal human scalp hair follicles (HFs), in particular, express both PRL and PRL receptors (PRL-R) at the mRNA and protein level. PRL and PRL-R immunoreactivity can be detected in the epithelium of human anagen VI HFs, while the HF mesenchyme is negative. During the HF transformation from growth (anagen) to apoptosis-driven regression (catagen), PRL and PRL-R immunoreactivity appear up-regulated. Treatment of organ-cultured human scalp HFs with high-dose PRL (400 ng/ml) results in a significant inhibition of hair shaft elongation and premature catagen development, along with reduced proliferation and increased apoptosis of hair bulb keratinocytes (Ki-67/terminal dUTP nick-end labeling immunohistomorphometry). This shows that PRL receptors, expressed in HFs, are functional and that human skin and human scalp HFs are both direct targets and sources of PRL. Our data suggest that PRL acts as an autocrine hair growth modulator with catagen-promoting functions and that the hair growth-inhibitory effects of PRL demonstrated here may underlie the as yet ill-understood hair loss in patients with hyper-prolactinemia.

PMID: 16507890 [PubMed - indexed for MEDLINE]

 

[abcdefg]

How does prolactin inhibit hair growth? What can be taken to inhibit prolactin?

 

[ripple-effect]

I'm not sure...just try to stop having orgasms. Even if there was a way...it would probably have some negative effect on your orgasm anyway.

 

[crespo]

This is why I take mucuna pruriens. It's supposed to inhibit prolactin.

 

[docj077]

There is a reason why physicians recommend that semen samples be collected 1-2 days without masturbation, but with no more than four days of abstinence.

Also, the hair follicles' response to prolactin is very much fourth dimensional with regards when it is actually susceptible to the actions of prolactin during hair follicle cycling. Prolactin receptor knockout models have hair growth anomalies. Hyperprolactinemia is associated with androgenic alopecia, amenorrhea, infertility, and hirsutism. Prolactin can also increase adrenal androgen production and attenuate 5AR activity both in vitro and in vivo. But, it is also important to remember that prolactin is also REQUIRED for proper hair growth in that administration of prolactin inhibitors can cause hair loss.

The male body is meant to be continuously sexual. We are designed that way in every way

 

[ripple-effect]

There is a reason why physicians recommend that semen samples be collected 1-2 days without masturbation, but with no more than four days of abstinence.

Why so? Is it b/c semen starts to degrade in quality? How does that relate?

Also, the hair follicles' response to prolactin is very much fourth dimensional with regards when it is actually susceptible to the actions of prolactin during hair follicle cycling. Prolactin receptor knockout models have hair growth anomalies. Hyperprolactinemia is associated with androgenic alopecia, amenorrhea, infertility, and hirsutism. Prolactin can also increase adrenal androgen production and attenuate 5AR activity both in vitro and in vivo. But, it is also important to remember that prolactin is also REQUIRED for proper hair growth in that administration of prolactin inhibitors can cause hair loss.

The male body is meant to be continuously sexual. We are designed that way in every way

How so if hyperprolactinemia is associated w/ hair loss?

 

[docj077]

There is a reason why physicians recommend that semen samples be collected 1-2 days without masturbation, but with no more than four days of abstinence.

Why so? Is it b/c semen starts to degrade in quality? How does that relate?

Exactly, after a particular period of abstinence sperm viability decreases.

Also, the hair follicles' response to prolactin is very much fourth dimensional with regards when it is actually susceptible to the actions of prolactin during hair follicle cycling. Prolactin receptor knockout models have hair growth anomalies. Hyperprolactinemia is associated with androgenic alopecia, amenorrhea, infertility, and hirsutism. Prolactin can also increase adrenal androgen production and attenuate 5AR activity both in vitro and in vivo. But, it is also important to remember that prolactin is also REQUIRED for proper hair growth in that administration of prolactin inhibitors can cause hair loss.

The male body is meant to be continuously sexual. We are designed that way in every way

How so if hyperprolactinemia is associated w/ hair loss?

Because, if you have hyperprolactinemia, you will not be continuously sexual. In fact, you'll likely have no sex drive at all. Case and point, the lowered libido associated with antidepressants.

Also, our sperm production is not seasonal or confined to particular times of the year. Men produce sperm continuously from puberty onward. If the male form wasn't designed for significant sexual activity, then we would not produce sperm in the quantities that we do for the duration that we do.

 

[docj077]

Also, it's important to take note that prolactin levels are only increased for an hour. Is such an increase even significant and how does that increase relate to the required prolactin necessary to inhibit hair growth during specific stages of the hair cycle in-vitro?

I highly doubt that the male body produces enough to cause significant hair growth inhibition.

 

[Chads don't bald]

Last seen 2019. Damn if he just waited 2 more years...

 

[Timii]

Last seen 2019. Damn if he just waited 2 more years...

Why?

 

[pegasus2]

Why?

He would know that prolactin is the real cause of hair loss and being a sexual degenerate speeds it up

 

[Jeju]

He would know that prolactin is the real cause of hair loss and being a sexual degenerate speeds it up

I have no chance in that case.

 

[coolio]

Some people just want to believe that masturbation is harmful. I've learned not to bother trying to debate it.

 

[Jeju]

Some people just want to believe that masturbation is harmful. I've learned not to bother trying to debate it.

I wouldn’t have abstained from sex even if it was guarantied to put me at NW7 at 25. I need it more than hair.

 

[justinbieberscombover]

Tell it to all the prematurely bald religious dudes who never fapped because they think it's a sin

 

[JaneyElizabeth]

Like 99 percent of men have any control over it. Until the church outlawed it, many priests and monks castrated themselves to stop the sexual imagery bombardment. The urge to procreate has to be pretty strong in men, else chicks would have to go looking themselves.

 

[StayPositive]

Tell it to all the prematurely bald religious dudes who never fapped because they think it's a sin

Faping is not the direct cause of male pattern baldness. Prolactin is. Faping and orgasm increase prolactin, so it speeds up hair loss.

 

[justinbieberscombover]

Faping is not the direct cause of male pattern baldness. Prolactin is. Faping and orgasm increase prolactin, so it speeds up hair loss.

Doesn't affect what I said lol

 

[JaneyElizabeth]

Faping is not the direct cause of male pattern baldness. Prolactin is. Faping and orgasm increase prolactin, so it speeds up hair loss.

Doesn't pregnancy cause rises in prolactin?

 

[StayPositive]

Doesn't pregnancy cause rises in prolactin?

Yes which causes baby blues