Replicel Is On Fire Lately — Data In Feb.

Ghostofchristmas

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Man ya'll niggas some pessimestic baldies.. lets think some good postive thoughts.. I still gotta propose Beyoncé before mofo Jay Z gives her another twin.. smh
 

nameless

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I just thought of something in connection with Replicel.

The big problem is that hair cells lose inductivity during culture. This prevents those cells from producing hairs. What if that problem is only a problem when it comes to growing NEW hairs but it's not such a big problem when it comes to just revitalizing already existing hairs?

If you look at Jahoda's experimental attempts to culture hair cells to re-implant and grow hair, it looks like his effort is to grow new follicles to create new hairs. If that's the case then the loss of inductivity problem (during mass pass culture) he's concerned with may only matter when attempting to create new follicles that grow new hairs. Loss of inductivity may not be such a big problem when it comes to just revitalizing already existing hairs.

If hair cells can be cultured and still have some ability to revitalize already existing follicles then perhaps these cultured cells can protect/preserve the hairs we already have even though they're unable to grow new follicles due to the loss of inductivity.

Growing new follicles and preserving your already existing hairs are not the same biological task. They're two different biological tasks. Just because cultured hair cells can't do one of these tasks (due to the loss of inductivity) doesn't mean that cultured hair cells definitely can't do the other biological task.
 
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irishlad87

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For anybody balding that finasteride has done nothing to help, i suggest you stop reading this thread as by the time it comes out it will be worthless to you if you are nw2 or more at the moment. As replicel said the earliest date in japan is 2019 so add another couple of years for rest of the world. Sorry for being so pessimistic but its the truth. Personally i hope brotzu/fidia surprise us all in the next year.
 

Pavi

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For anybody balding that finasteride has done nothing to help, i suggest you stop reading this thread as by the time it comes out it will be worthless to you if you are nw2 or more at the moment. As replicel said the earliest date in japan is 2019 so add another couple of years for rest of the world. Sorry for being so pessimistic but its the truth. Personally i hope brotzu/fidia surprise us all in the next year.

They actually said earliest is the end of 2018
 

lemoncloak

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Growing new follicles and preserving your already existing hairs are not the same biological task.
Yes they are, for our purposes. Preserved follicles still have to cycle normally and dermal papillas still have to send all the necessary signals for this to happen. You could say they're different in that preserving the follicle doesn't need the original formation we see maintained through telogen but my previous point still stands. Plus, I think forming a follicle has more to do with proper structure of the cells. When Tsuji tried injecting a bunch of dp's and stem cells to grow hair it didn't work, he had to keep them closely together in collagen gel. Replicel isn't doing that, so unless dsc cells have properties I'm not aware of, like 1 of them multiplying into numerous dp's in the skin and recruiting epithelial stem cells, then it seems reasonable to expect replicel not to grow new hairs.
 

Pablo234

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HI GUYS.

Can someone tell me the reason as to why the 12 and 24 month efficacy data was locked until the 5 year period was up? Is this a standard protocol, or is it at discression of the company?

Also, this being the case with the results being locked ... does this mean that Shiseido themselves will not have seen the 12 and 24 month efficacy data results, before signing their licensing deal?

Sorry if this has been Brought up before,
 

Toccata

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Replicel just tweeted this:
Next week looks very exciting.

For Replicel everything is exciting. Future is exciting, data is exciting, February is veeeeery exciting.

Follica has been very exciting:

"We are very excited about the progress and are pushing forward with our programs. Everything is going very well and management, the board, and the Scientific Advisory Board are all extremely encouraged by our scientific progress and results."—Follica Statement, January 2010

"Things are going really well—it’s really exciting." —Daphne Zohar Follica Co-Founder, June 2010

and Histogen—exciting:

"With the exciting data we have gained over the past year, particularly in hair and cancer applications, Histogen has regained a strong position with investors and potential partners[...]" Eileen Brandt Histogen spokeswoman, November 2010

"We are excited to build on the momentum Histogen has created over the past two years[...]"—Gail K. Naughton CEO, November 2010


...SEVEN YEARS LATER, Replicel is in on the excitement:

"We are now prepared for what is − without question or hyperbole − the single most exciting year in the Company’s history." —Lee Buckler Replicel CEO, 2017 Statement

And Cassiopea (Breezula CB-03-01):
"2015 was an exciting and productive year"—Diana Harbort, Cassiopea CEO 2016 Statement

And Hairclone:
"2017 will be a very exciting one for us here" —Hairclone Tweet, January 2017

I don't know how many more years of this excitement I can take!
this hairloss game is brutal man.
 

sunchyme1

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Follica has been very exciting:

"We are very excited about the progress and are pushing forward with our programs. Everything is going very well and management, the board, and the Scientific Advisory Board are all extremely encouraged by our scientific progress and results."—Follica Statement, January 2010

"Things are going really well—it’s really exciting." —Daphne Zohar Follica Co-Founder, June 2010

and Histogen—exciting:

"With the exciting data we have gained over the past year, particularly in hair and cancer applications, Histogen has regained a strong position with investors and potential partners[...]" Eileen Brandt Histogen spokeswoman, November 2010

"We are excited to build on the momentum Histogen has created over the past two years[...]"—Gail K. Naughton CEO, November 2010


...SEVEN YEARS LATER, Replicel is in on the excitement:

"We are now prepared for what is − without question or hyperbole − the single most exciting year in the Company’s history." —Lee Buckler Replicel CEO, 2017 Statement

And Cassiopea (Breezula CB-03-01):
"2015 was an exciting and productive year"—Diana Harbort, Cassiopea CEO 2016 Statement

And Hairclone:
"2017 will be a very exciting one for us here" —Hairclone Tweet, January 2017

I don't know how many more years of this excitement I can take!

loooooooooool

best post of the day
 

DrizzyD

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Well now that @MM87 has trolled and brought to light failure after failure occurring for the last 10 years, it's safe to say I've lost all hope lmfao
 

br1

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Follica has been very exciting:

"We are very excited about the progress and are pushing forward with our programs. Everything is going very well and management, the board, and the Scientific Advisory Board are all extremely encouraged by our scientific progress and results."—Follica Statement, January 2010

"Things are going really well—it’s really exciting." —Daphne Zohar Follica Co-Founder, June 2010

and Histogen—exciting:

"With the exciting data we have gained over the past year, particularly in hair and cancer applications, Histogen has regained a strong position with investors and potential partners[...]" Eileen Brandt Histogen spokeswoman, November 2010

"We are excited to build on the momentum Histogen has created over the past two years[...]"—Gail K. Naughton CEO, November 2010


...SEVEN YEARS LATER, Replicel is in on the excitement:

"We are now prepared for what is − without question or hyperbole − the single most exciting year in the Company’s history." —Lee Buckler Replicel CEO, 2017 Statement

And Cassiopea (Breezula CB-03-01):
"2015 was an exciting and productive year"—Diana Harbort, Cassiopea CEO 2016 Statement

And Hairclone:
"2017 will be a very exciting one for us here" —Hairclone Tweet, January 2017

I don't know how many more years of this excitement I can take!

You didn't get me excited with this !
 

NNocim

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Well now that @MM87 has trolled and brought to light failure after failure occurring for the last 10 years, it's safe to say I've lost all hope lmfao
I feel liberated now:D:rolleyes:

EDIT: and it seems that all my posts are gone and I've been stripped of all my likes *lol* :(:rolleyes:
thanks @administration.

EDIT2: I am saying good bye. I am returning to German Board Alopezie.de
 
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Follisket

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Well now that @MM87 has trolled and brought to light failure after failure occurring for the last 10 years, it's safe to say I've lost all hope lmfao

And reminders like that are exactly what we need. We're still doing the exact same thing as before but expecting different results. We can't possibly claim we mind balding when we've done absolutely nothing differently to bring about change.

As today's treatments in development start to crumble we just look for new ones to latch onto, reset the countdown and that's it. Rinse and repeat. Exactly what baldies have been doing since forever. Getting by on illusions until they die -- bald.
 

NNocim

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And reminders like that are exactly what we need. We're still doing the exact same thing as before but expecting different results. We can't possibly claim we mind balding when we've done absolutely nothing differently to bring about change.

As today's treatments in development start to crumble we just look for new ones to latch onto, reset the countdown and that's it. Rinse and repeat. Exactly what baldies have been doing since forever. Getting by on illusions until they die -- bald.
Indeed! You are so right. But what can we do about it?
 

hanginginthewire

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Jesus God you guys have made me depressed. Where is That Guy? Where is someone with some objective hope? Why has everything gone to sh*t? ☹️
 

CharAblaze

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But what can we do about it?
Choose:
1)Start a f*****g movement to raise awareness of the problem (there are plenty of ridiculous ones and TBH ours will not look as ridiculous as nofapsters). If it gets popular, it will show the demand.
2)Get rich and fund your own treatment. (Like Sammumed dude did)
3)Make a f*****g kickstarter to fund a treatment (Somebody will probably take your money and run away and it is always risky, it may not even work).
4)Waiting game (Wait for Brotzu, Histogen, Follica, etc., etc.. until your youth is over or you die)
5)Cry in a corner or pretend that you don't give a f*** about balding.
 
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NNocim

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Choose:
1)Start a f*****g movement to raise awareness of the problem (there are plenty of ridiculous ones and TBH ours will not look as ridiculous as nofapsters). If it gets popular, it will show the demand.
2)Get rich and fund your own treatment. (Like Sammumed dude did)
3)Make a f*****g kickstarter to fund a treatment (Somebody will probably take your money and run away and it is always risky, it may not even work).
4)Waiting game (Wait for Brotzu, Histogen, Follica, etc., etc.. until your youth is over or you die)
5)Cry in a corner or pretend that you don't give a f*** about balding.
You stepped on my feet :D:rolleyes:

How about 6.) Write a letter to Elon Musk and ask him if he is willing to cure baldness!?

EDIT: If Adi was still around, we would be cured like 30 years ago...
 

nameless

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Yes they are, for our purposes. Preserved follicles still have to cycle normally and dermal papillas still have to send all the necessary signals for this to happen. You could say they're different in that preserving the follicle doesn't need the original formation we see maintained through telogen but my previous point still stands. Plus, I think forming a follicle has more to do with proper structure of the cells. When Tsuji tried injecting a bunch of dp's and stem cells to grow hair it didn't work, he had to keep them closely together in collagen gel. Replicel isn't doing that, so unless dsc cells have properties I'm not aware of, like 1 of them multiplying into numerous dp's in the skin and recruiting epithelial stem cells, then it seems reasonable to expect replicel not to grow new hairs.



I've been saying the same things you just said for some time, but there is the issue that both Aderans and Intercytex did report stabilization of hair loss and small increases in hair counts.

And I never saw the study by Tsuji where he injected dp's and stem cells so I cant speak to his results. Can you please provide a link to that study (dp + stem cells injections) by Tsuji?
 

lemoncloak

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I've been saying the same things you just said for some time, but there is the issue that both Aderans and Intercytex did report stabilization of hair loss and small increases in hair counts.

And I never saw the study by Tsuji where he injected dp's and stem cells so I cant speak to his results. Can you please provide a link to that study (dp + stem cells injections) by Tsuji?
Small increases maybe :/ but how small?
Not aware of a study. Look at shiseido's video part 2. He says it himself. Here
 
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