Samumed Sm04554 Results Normalized To Baseline

[Johnson40]

Having it be an injection is bound to be a pain tho.
You'd have to find a clinic near to do it for you in a safe environment, and hair restoration clinic always pump up the price too.

sh*t, i mean in my country the most extensive non surgical treatment you can usually find is minoxidil 2%, "vitamins mesotherapy" and maybe fina.
Even if it's out in 2024, you can bet your *** it'll be a pain to find.

 

[Throwaway94]

If it works, every man will want this. Expect prices to drop fast, the demand for this will be sky high if it really is as promised (1 injection every 2 years, no side effects)

It's not one injection it was 12

 

[surfer9]

Man, if I could inject some stuff in my scalp and have a full head of hair I'd be crying, I'd be euphoric. The girl that just rejected me.... bumping into her with a full head of hair would be an amazing feeling. She'd be shook.

 

[LouisSarkozy]

is hmi supposed to be out in 2024? i need to cope badly rn

 

[Chads don't bald]

10-20k every 2 years is still pretty steep tbh

 

[Johnson40]

is hmi supposed to be out in 2024? i need to cope badly rn

It's only an estimation, if i wanted to be pessimistic i'd say some postponing is bound to happen.
And i'll assume you're French, but sorry frérot but if it comes out as some sort of mesotherapy, it'll be a pain to find here, just look at the horrendous state and the lag of modern hair restoration clinics and dermatologists.

SMI-6 hitting the grey market could be a good alternative in the mean time, we should try to push this for big sellers.

10-20k every 2 years is still pretty steep tbh

Macaques managed to keep their hair for 4 years, they seemed to have lost very little, but then again it's on macaques.
It's possible that humans don't keep them half as long.

And sh*t, if you can buy 2 years drug free, if you're willing to add something to that, you might last long enough for better treatment to eventually come out.

 

[scientist_0005]

It's only an estimation, if i wanted to be pessimistic i'd say some postponing is bound to happen.
And i'll assume you're French, but sorry frérot but if it comes out as some sort of mesotherapy, it'll be a pain to find here, just look at the horrendous state and the lag of modern hair restoration clinics and dermatologists.

SMI-6 hitting the grey market could be a good alternative in the mean time, we should try to push this for big sellers.


Macaques managed to keep their hair for 4 years, they seemed to have lost very little, but then again it's on macaques.
It's possible that humans don't keep them half as long.

And sh*t, if you can buy 2 years drug free, if you're willing to add something to that, you might last long enough for better treatment to eventually come out.

honestly to me the most likely outcome is that this produces results comparable to what replicel accomplished, some small effect and then they will say yes yes statistically significant and we may develop it further and then you wont hear from it ever again. just the fsct that prolactin is not involved in any of the major pwthways knows to cause regression of hair is a red flag already. although if it sas that obvious surely they would not have bought the rights bc they are biotechnologists and probably know what they are doing

 

[Johnson40]

honestly to me the most likely outcome is that this produces results comparable to what replicel accomplished, some small effect and then they will say yes yes statistically significant and we may develop it further and then you wont hear from it ever again. just the fsct that prolactin is not involved in any of the major pwthways knows to cause regression of hair is a red flag already. although if it sas that obvious surely they would not have bought the rights bc they are biotechnologists and probably know what they are doing

I wouldn't be so sure, prolactin is known to cause hair loss in women by precipitating the follicles in the telogen phase.
Which is how miniaturization might work at the end of the day, a shortening the anagen phase, it wouldn't to be too far fetched to think that it might play a role just from that, not even talking about the other direct role of PRL across various proteins, i believe a scheme was posted by guys on the group buy.

We should keep our expectations in check for that one, but the fact that the treatment had the same result on macaque as finasteride and RU ( At least from numbers alone, i never really found a way to compare as they used some sort of subjective definitions for different areas ) despite acting on another pathway is encouraging on its own.
The 4 years hair might be specifics to the macaques, but that make one man dream.
The funds invested in this apparently expensive treatment is also a good reason to have hope.

 

[John Difool]

Ouch a couple of million dollars for 10g. We could see Bezos topping a lion mane pretty soon. If we know HMI-115 is the cure, what's the closest to HMI we can get know (for less than one million dollar)?

 

[werefckd]

When are they supposed to start testing that HMI treatment in humans?

 

[John Difool]

That's stuff will land before 2030 so at least there is a possibility. In related news, Tsuji san is out of the equation:
Last BS article from him was:

Article expired

News on Japan, Business News, Opinion, Sports, Entertainment and More

www.japantimes.co.jp

 

[LouisSarkozy]

Its nor really the cure if u seen the monkeys pic you would see most of the regrowth were thin hair that became thick

indeed and i have no idea and it's just how i cope now but but for slick bald area on the hairline and temples if ones manage to get small vellus thanks to follica then turning those vellus into longer " thin" "diffuse looking hair" thanks to bay maybe after that using a wnt agonist or some other other sort of growth stimulant we could manage to get cosmetically acceptable looking hair on previously bald area on the front.

and if not i'll just rope. i'm holding up and fighting till 2025 then i give up for good

 

[LouisSarkozy]

You talk about follica like its not derma device with the same minoxidil …

but this treatment wont deliver anything new.

we only need vellus for bay to work right? i'm doing oral+topical min + dermaroller ( as per follica is doing) and i'm covered in vellus hair down to Norwood-1 area but they just won't f*****g grow no matter what so i'm praying and coping till bay comes out and hopefully turn them terminal

 

[justinbieberscombover]

indeed and i have no idea and it's just how i cope now but but for slick bald area on the hairline and temples if ones manage to get small vellus thanks to follica then turning those vellus into longer " thin" "diffuse looking hair" thanks to bay maybe after that using a wnt agonist or some other other sort of growth stimulant we could manage to get cosmetically acceptable looking hair on previously bald area on the front.

and if not i'll just rope. i'm holding up and fighting till 2025 then i give up for good

 

[LouisSarkozy]

We need to wait for human trails first…

when are they supposed to be conducted? ...

 

[Catagen]

I think we are at a point where its safe to say its a failure, @pegasus2 was right guys.

 

[John Difool]

There is a higher probability for the tooth fairy to exist than for SM to deliver any results. I feel sorry for those still waiting for the tooth fairy to visit them. How should I feel about the ones waiting for SM results?

 

[John Difool]

Maybe worth for some of you thinking that 2025 is the deadline for a miracle drug to start adopting other protocols now till the miracle materialize. The trend on new experiments in 2021 is going strong. I personally created a group buy on UT-34 and I am sorry if some of you missed it but there are other less costly alternatives at this time. Please refer to my low/medium/high budget I posted in one of the group buy thread (ARV-110 & WAY200070, iirc)

 

[John Difool]

Recap of the timeline:

Oct 30, 2019: first post
Samumed Sm04554 Results Normalized To Baseline

On Feb 5, 2020 Pegasus puts some water on the fire and writes:
Not even close to a cure. I guarantee you it is not even as effective as minoxidil or finasteride.

Now I'm 100% convinced this guy is a scammer trying to inflate his valuation to dupe investors out of their money. Pay no attention to Samumed. I'm sure SM04554 works to a degree, but I doubt it's as effective a wnt disinhibitor as is WAY.

NoMoney promptly replies: on the same day
1. he is too famous to be a Scammer. Everybody knows him. (Forbes, Tv, politician )
2. his CV is too impressive. He demonstrated that he is able to etabilish such companies.
3. He did clinical trials in many different cases in arrangement with the FDA. And he showed the results.
4. His team is very competent and famous. I cant imagine, that they would risk to lose everything for more Money.
They're all rich anyway (!!!)

What follows is an exchange between an ignorant crowd of believers and Samumed fans who can't tell the difference between terminal and vellus hair and pegasus trying to enlighten them, generously giving his time to educate a few ready to listen (myself included).

52 pages later or more than 2 years later, on Dec 3, 2021 some people finally realize this was a scam:
I think we are at a point where its safe to say its a failure, @pegasus2 was right guys.

What's next? People who are high or completely naive will continue to believe SM is an effective treatment for hair loss. This thread will probably expand to 100 pages before the. most stubborns open. their eyes.

At a minimum, all the folks who posted that pegasue would be wrong need to DM him a personal apology.

 

[sonictemples]

Didn’t they remove the molecule from their pipeline too?