Sandalore - Chemical Used In Perfumes To Mimic Sandalwood Triggers Growth?

[BaldLion]

I finally faced the reality. I have returned to dutasteride everyday and all shedding rapidly disappeared over 4 weeks. This defines duta as irreplaceable. time to look intensely for chinese CB suppliers.
to all people complaining about shedding with sandalore: it's because you're not taking finasteride.

Do you mean that sandalore is useless or just that finasteride/dutasteride is way better than sandalore?
Do you considere sandalore as a complement or useless, that's my question

 

[INT]

I finally faced the reality. I have returned to dutasteride everyday and all shedding rapidly disappeared over 4 weeks. This defines duta as irreplaceable. time to look intensely for chinese CB suppliers.
to all people complaining about shedding with sandalore: it's because you're not taking finasteride.

You should have added a few 'in my opinion' and 'based on my experiences' in there...

Just because it doesn't do anything for you does not mean this will be the case for other people.

 

[NotInmywatch]

Do you mean that sandalore is useless or just that finasteride/dutasteride is way better than sandalore?
Do you considere sandalore as a complement or useless, that's my question

In my case I can now conclude that duta makes 99% of the work and the remaining 1% is divided between sandalore, cetirizine, LLLT, PRP, nizoral. not completely useless, but very weak.
any researcher/physician would agree with what I'm saying, it's just that it's hard to accept that you're indefinitely bound to a dangerous drug.

 

[Vinc2097]

In my case I can now conclude that duta makes 99% of the work and the remaining 1% is divided between sandalore, cetirizine, LLLT, PRP, nizoral. not completely useless, but very weak.
any researcher/physician would agree with what I'm saying, it's just that it's hard to accept that you're indefinitely bound to a dangerous drug.

Duta block nearly 100 % of DHT, you could drop anything else in your regimen and it wouldnt change anything i guess..

 

[BaldLion]

Duta block nearly 100 % of DHT, you could drop anything else in your regimen and it wouldnt change anything i guess..

Dutasteride block close to 100% in your bloodstream but in your scalp, it remove "only" 50% so it's far to block 100% DHT

 

[INT]

any researcher/physician would agree with what I'm saying, it's just that it's hard to accept that you're indefinitely bound to a dangerous drug.

Fallacy. Sandalor eis still an experimental treatment, we KNOW that it is not clear yet how good of a treatment it will be for male pattern baldness. That is why were are all testing it.

 

[NotInmywatch]

Fallacy. Sandalor eis still an experimental treatment, we KNOW that it is not clear yet how good of a treatment it will be for male pattern baldness. That is why were are all testing it.

well, what do you think about the results so far?

 

[INT]

well, what do you think about the results so far?

My own?

 

[NotInmywatch]

My own?

yes, and what you have witnessed on this thread.
the sandalore thread on tressless died so I think this the only place.

 

[Vinc2097]

Dutasteride block close to 100% in your bloodstream but in your scalp, it remove "only" 50% so it's far to block 100% DHT

wouldnt be topical duta a better option then ?

 

[NotInmywatch]

wouldnt be topical duta a better option then ?

well yes and no. problem is that duta and fina are designed to fool the 5 alpha reductase and in order to do so they chemically resemble testosterone, due to that they have inherent systemic absorption capabilities (like testosterone transdermal patches).
I don't know if there's a way to contain these molecules in the topical zone. polichem trial did not post DHT blood levels results, because they didn't want to scare anybody.

CB instead relies into the systemic bloodstream conversion to cortexolone once it crosses the topical zone.

 

[Bushi]

People complaining about shedding on Sandalore.. doesn’t Minoxidil cause shedding at the start too and then starts to work it’s magic.

Thought about that aswell, the shock effect. But than again sandalore slows down dead of hair follicle and boost their growth. If it slows down dead of a follicle, than it wouldn't fall out.

 

[Vinc2097]

well yes and no. problem is that duta and fina are designed to fool the 5 alpha reductase and in order to do so they chemically resemble testosterone, due to that they have inherent systemic absorption capabilities (like testosterone transdermal patches).
I don't know if there's a way to contain these molecules in the topical zone. polichem trial did not post DHT blood levels results, because they didn't want to scare anybody.

CB instead relies into the systemic bloodstream conversion to cortexolone once it crosses the topical zone.

so i guess topical CB would be way better than topical fina .?

 

[NotInmywatch]

so i guess topical CB would be way better than topical fina .?

so far CB results at 6 month mark surpass fina at 1 year mark.
the reason it's very obvious: CB is an androgen receptor blocker, whereas fina is a DHT synthesis blocker
testosterone alone is killing your hair at 1/10 speed of DHT, so CB protects against both T and DHT.

 

[kungfukenny]

so far CB results at 6 month mark surpass fina at 1 year mark.
the reason it's very obvious: CB is an androgen receptor blocker, whereas fina is a DHT synthesis blocker
testosterone alone is killing your hair at 1/10 speed of DHT, so CB protects against both T and DHT.

I thought both CB and finasteride were AA’s?

 

[NotInmywatch]

I thought both CB and finasteride were AA’s?

fina and duta have antiandrogen properties but they do not block the androgen receptor. that would be catastrophic, it would cause secondary hypogonadism to all patients. they only block T to DHT conversion, which in theory would keep your T levels within a safe range.

 

[Alex Contee]

Sad to say that I am dropping this from my regimen. I have ridden out countless min, finasteride, oral min, etc sheds but the last 2 months have decimated my hair. Without knowing the proper dose or seeing any success stories, it’s a hard ask to continue.

Even if the shed hadn’t been this bad, the stuff turns my hair texture into crap. I have also noticed increased acne near the hairline which I have never had in my adult life. I’ll be keeping an eye out to see if anyone has success. I would be willing to try again in the future.

 

[NotInmywatch]

I have read some relatively good reports in a spanish forum. They started with a product that seems to have sandalore already ("Bioscalin" or something) and then they switched to the homemade version because of the price. There is even a girl that claims this has been a game-changer for her.

However, I see two main differences between this recipe and the spanish recipe:
1. They use low sandalore concentrations: maximum 0.2%
2. They don't use propylene glycol but something called "transcutol" in a vewy low concentration. According to google, "transcutol" is "Diethylene glycol monoethyl ether". I could not find it in my country so I could not try it yet, but I plan to do it so. Some people also replaces the "transcutol" by DSMO, also in low concentrations.

Also, some people is using 40 degrees vodka instead of pure alcohol: it seems it is less irritative than pure alcohol.

assuming their ex vivo results are not fake, the patent states that the therapeutic range is 0.1%-10%
but the authors also said that too much sandalore could inhibit hair growth.
so maybe 0.5% is too much. or maybe 0.1% is too much. we really don't know.
thinking of it, I could try 0.05% in 10 months and see what happens.
transcutol is superior to ethanol in several parameters like solubilization power, boiling point, but that does not mean that ethanol does not work as a penetration enhancer.

 

[NotInmywatch]

if ethanol irritation were capable of generating shedding, people would complain of hairless hands due to daily use of ethanol-hand sanitizer.

they're shedding because they're not taking finasteride. hair loss is in 96% of cases androgen-related.

 

[ElonMusk]

I guess this ended up being a failure?