Setipiprant - Frequently Asked Questions

[Georgie]

Lyphar

You using VPA or LiCl? Just wanting some advice on how to mix the topical VPA preferably. I know stemox is a good vehicle, but unsure what dose people are using to mimic the 8.3-11% used in studies. Cheers.

 

[ZenHead]

You using VPA or LiCl? Just wanting some advice on how to mix the topical VPA preferably. I know stemox is a good vehicle, but unsure what dose people are using to mimic the 8.3-11% used in studies. Cheers.

I tried licl after wounding a few times at 8.3%, but the day after I would shed an absolutely insane amount of hair in the shower. Like almost 5 days worth of regular shedding for me in just one shower. That freaked me out so I stopped

 

[Georgie]

I tried licl after wounding a few times at 8.3%, but the day after I would shed an absolutely insane amount of hair in the shower. Like almost 5 days worth of regular shedding for me in just one shower. That freaked me out so I stopped

Yikes. f*** that. Are you rolling or stamping? I used to shed 2-3x more on the days of and after rolling, but never stamping. I’m probably more interested in VPA given the studies if it’s efficacy in comparison to LiCl. Worries me that I can f*** with biotin but I guess supplements can help that. Just need to know the relavent dose/ml of stemox.

 

[Alex Contee]

I tried licl after wounding a few times at 8.3%, but the day after I would shed an absolutely insane amount of hair in the shower. Like almost 5 days worth of regular shedding for me in just one shower. That freaked me out so I stopped

8.3% was the amount used in the VPA study. I strongly recommend not using LiCi at more than 3% or else you are going to shed like crazy. It can also cause some significant health issues at a dose that high. Swiss and his (former?) followers use(d) between 10-20mg in 1ml of distilled water.

 

[Alex Contee]

You using VPA or LiCl? Just wanting some advice on how to mix the topical VPA preferably. I know stemox is a good vehicle, but unsure what dose people are using to mimic the 8.3-11% used in studies. Cheers.

I unfortunately can't link to it because I am too new but the vehicle used in the study was "50% (vol/vol) ethanol, 30% water, and 20% propylene glycol." VPA has some promising science behind it but it can cause hair loss from prolonged oral use due to zinc and biotin depletion. I am not convinced it is a long term solution which sucks because I have a gut feeling it works better than LiCi.

 

[Georgie]

I unfortunately can't link to it because I am too new but the vehicle used in the study was "50% (vol/vol) ethanol, 30% water, and 20% propylene glycol." VPA has some promising science behind it but it can cause hair loss from prolonged oral use due to zinc and biotin depletion. I am not convinced it is a long term solution which sucks because I have a gut feeling it works better than LiCi.

I’ve read a few threads that say it’s easily dissolved in stemoxydine. Maybe minoxidil would be a better vehicle?
Surely you could supplement with zinc and biotin to take care of that.

 

[omega]

The Seti is in not effect against the RU or minoxidil? Can I mix Seti with Minoxidil? I want the 2 grams of raw Seti powder into the 60ml Foligain (5% Minoxidil) bottle and mix.(few drops of DMI??) Foligain is 5% Minoxidil and inactive ingredients: Propylene Glycol, Purified Water, and Ethyl Alcohol.

 

[Georgie]

The Seti is in not effect against the RU or minoxidil? Can I mix Seti with Minoxidil? I want the 2 grams of raw Seti powder into the 60ml Foligain (5% Minoxidil) bottle and mix.(few drops of DMI??) Foligain is 5% Minoxidil and inactive ingredients: Propylene Glycol, Purified Water, and Ethyl Alcohol.

Take it orally. Easier and more effective.

 

[omega]

Take it orally. Easier and more effective.

I don't want to use it orally because of side effects

 

[heyhey]

I don't want to use it orally because of side effects

What sides did you get?

 

[omega]

What sides did you get?

I didn't get sides.. But.. Slide up and read to #221 jonnywalker93, Monday at 3:37 AM...

Plus #1 westonci, Jan 24, 2018

Side effects
The only one that seems to pop up is sleep issues.....
Another member of the private forum had sleep issues at 2g/day and started taking glutathione and says he sleeps like a baby now.

I think so topical use is safer..

 

[whatevr]

I think so topical use is safer..

Westonci proves that the oral works, I haven't seen anyone maintain with the topical yet.

 

[omega]

Westonci proves that the oral works, I haven't seen anyone maintain with the topical yet.

I know, but my possible protocol:

1x1 Seti (topical)
1x1 Ru and minoxidil mix (topical)
1x1 Revita or Bio hemp seed shampoo - (A) day - Revita, (B) day - Bio hempseed shampoo
once a week - UVB light
once a week - dermaroller (0,5mm)
diet change (omega-3, omega-6 ratio a positive impact to PGE2 and PGD2)
3x10 drops CBD oil in hempseed oil per day (omega-3, omega-6 ratio a positive impact to
PGE2 & PGD2 --- CBD maybe is PGD2 inhibitors (???) - http://mct.aacrjournals.org/content/12/1/69
2x1 - 1 teaspoon hempseed oil per 2 day (omega-3, omega-6 and antioxidants on hair loss)
2x1 - 1 teaspoons Omega-3 per 2 day

I think it will work..
So I don't want to chemicals for oral use..

 

[Jonnyyy]

I know, but my possible protocol:

1x1 Seti (topical)
1x1 Ru and minoxidil mix (topical)
1x1 Revita or Bio hemp seed shampoo - (A) day - Revita, (B) day - Bio hempseed shampoo
once a week - UVB light
once a week - dermaroller (0,5mm)
diet change (omega-3, omega-6 ratio a positive impact to PGE2 and PGD2)
3x10 drops CBD oil in hempseed oil per day (omega-3, omega-6 ratio a positive impact to
PGE2 & PGD2 --- CBD maybe is PGD2 inhibitors (???) - http://mct.aacrjournals.org/content/12/1/69
2x1 - 1 teaspoon hempseed oil per 2 day (omega-3, omega-6 and antioxidants on hair loss)
2x1 - 1 teaspoons Omega-3 per 2 day

I think it will work..
So I don't want to chemicals for oral use..

Seti once a day? Why not twice

 

[omega]

Seti once a day? Why not twice

Because I use seti in the morning. and I use ru and minoxidil at night.
But the seti was dissolved in the minoxidil. So, 2x1 seti / day topical.

I was ordered from kane, but I hope it is not fake.. the seti powder has a similar smell like a Amphetamine
The seti on my hair similar to hairspray.

I don't know if this a seti can work, BUT I increase the PGE2 with UVB sunburns and Castrol.

did Sulfasalazine work for someone?

EDIT:

I read somewhere that pge2 has an opposite effect on pgd2. Its true?

 

[alebaba]

Because I use seti in the morning. and I use ru and minoxidil at night.
But the seti was dissolved in the minoxidil. So, 2x1 seti / day topical.

I was ordered from kane, but I hope it is not fake.. the seti powder has a similar smell like a Amphetamine
The seti on my hair similar to hairspray.

I don't know if this a seti can work, BUT I increase the PGE2 with UVB sunburns and Castrol.

did Sulfasalazine work for someone?

EDIT:

I read somewhere that pge2 has an opposite effect on pgd2. Its true?

I'm thinking about trying uvb sunburn to get more pge2, is it painful?

You have a pretty dam good regimen, I hope you do 15% seti twice daily. You should make daily batches for seti, if you threw all the seti into minoxidil, its going to oxidize in about 5 days.

Westonci proves that the oral works, I haven't seen anyone maintain with the topical yet.

Topical is better than oral, imo.

 

[omega]

I'm thinking about trying uvb sunburn to get more pge2, is it painful?

No. Try it.

You have a pretty dam good regimen, I hope you do 15% seti twice daily. You should make daily batches for seti, if you threw all the seti into minoxidil, its going to oxidize in about 5 days.

I use the 2.5 grams of raw seti powder in the 60ml 5% minoxidil.

Setipiprant seems to mostly be used as a 4% solution, which means 40mg per 1ml of vehicle. So if you have more area that you want to cover, or want to try a higher dosage, you would keep the proportion the same, like by mixing 80mg with 2ml.

https://sites.google.com/site/groupbuyfunding/how-to-use-setipiprant

Why its going to oxidize in about 5 days?

Topical is better than oral, imo.

I agree
https://ask.fm/swisstemples/answers/134325570156

 

[whatevr]

agree
https://ask.fm/swisstemples/answers/134325570156

Vehicle is the problem.

 

[omega]

Vehicle is the problem.

okay. but why? please explain to me.
can the cetrizin be an alternative to a seti? https://www.hairlosstalk.com/interact/threads/pgd2-regimen-and-results-cetirizine-water.68953/
https://www.ncbi.nlm.nih.gov/pubmed/28604133?dopt=Abstract

 

[HairSuit]

No. Try it.



I use the 2.5 grams of raw seti powder in the 60ml 5% minoxidil.


https://sites.google.com/site/groupbuyfunding/how-to-use-setipiprant

Why its going to oxidize in about 5 days?


I agree
https://ask.fm/swisstemples/answers/134325570156

That’s interesting. I will say this. It’s crazy how quickly oral seti has decreased my shedding. That said, I am uneasy about using it orally, because it will hit all the receptors in the body. If it worked as well topically as it does orally, I would jump on it.