Sperm Production and long term finasteride use - study....

[docj077]

If you read the abstract carefully enough, you'll realize that the fertility status of those men was not measured pre-finasteride. Thus, neither the researchers or anyone here can form an educated opinion about the study. They may have all had fertility issues to begin with, so the FULL study needs to be posted.

 

[RaginDemon]

sh*t like this just scares me lol

 

[powersam]

3 people, recruited at a male infertility clinic, who could very well have had all those issues beforehand. this study is worth nothing.

actual controlled studies have shown that any small changes in sperm quality are reversed after discontinuing the medication.

 

[harold]

I have read the full study. What many of you are failing to note that it is a case study and is not pretending to be a full double-blind study with 1000s of subjects. That doesn't make it worthless. Yes the threee men may have had fertility isssues before starting finasteride. Thats not the point. The point is that in all 3 after no other treatment than discontinuation of the drug did measures of sperm quality improve. More worryingly while measures of morphology and motility improved in all 3 they all still showed elevations in meiotic abnormalities - more sperm being formed with the wrong number of chromosomes.
Again its only 3 people. But in finding something like this you publish it. If others come across the same thing or make a similar connection in their patients they publish/report also. Maybe someone does a more comprehensive study to look at the issue. Thats the point.
At the end of the day it is what it is. If someone wants that translated for them as "Never take finasteride your balls will drop off" or "There is absolutely wrong that can go wrong from blocking 5-alpha reductase enzymes in the body" then thats your own business.
hh

 

[TonyTheTiger]

I have read the full study. What many of you are failing to note that it is a case study and is not pretending to be a full double-blind study with 1000s of subjects. That doesn't make it worthless. Yes the threee men may have had fertility isssues before starting finasteride. Thats not the point. The point is that in all 3 after no other treatment than discontinuation of the drug did measures of sperm quality improve. More worryingly while measures of morphology and motility improved in all 3 they all still showed elevations in meiotic abnormalities - more sperm being formed with the wrong number of chromosomes.
Again its only 3 people. But in finding something like this you publish it. If others come across the same thing or make a similar connection in their patients they publish/report also. Maybe someone does a more comprehensive study to look at the issue. Thats the point.
At the end of the day it is what it is. If someone wants that translated for them as "Never take finasteride your balls will drop off" or "There is absolutely wrong that can go wrong from blocking 5-alpha reductase enzymes in the body" then thats your own business.
hh

Damn I am gonna go off finasteride now! because I dont want my kids to have abnormalities! so basically the sperm is tampered wtih before and the that meats the child will end up with birth defects?

Damn

its also funny how it seems more men who take propecia must not be getting laid or having children. Cause how come you never see cases of men on propecia having kids while on it?

 

[harold]

There is no basically about it. Everyone wants a bottom line "You are fucked if you take finasteride" "You will be absolutely fine guaranteed and nothing will go wrong" and you are not going to get that kind of certainty. And I dont know what you mean by not seeing cases of guys on finasteride having kids. Its not like they have a red mark on their forehead that lets you nkow they are on the drug.
hh

 

[TonyTheTiger]

There is no basically about it. Everyone wants a bottom line "You are f***** if you take finasteride" "You will be absolutely fine guaranteed and nothing will go wrong" and you are not going to get that kind of certainty. And I dont know what you mean by not seeing cases of guys on finasteride having kids. Its not like they have a red mark on their forehead that lets you nkow they are on the drug.
hh

I mean you just never hear about it? most of the guys on these hairloss boards seem to be single and dwell on there hair too much most girls dont like that I guess.

I know only one guy on here had a kid while on finasteride thats about it.

I guess its just a gamble when you take finasteride.

Accutane can also cause birth defects as well.

Just sucks I wanna have kids one day but my profession if I go bald I wont get jobs especially have a baby face and balding it doesnt look right. I already am thinning on my crown.

 

[abcdefg]

Whether anyone believes or not I personally think finasteride or dht effects male sexual functioning. Some men I guess most dont get noticeable sexual sides but that doesnt mean something doesnt happen to you that you cant feel or notice. I think for some reason dht is tied together with sexual function to some degree.

 

[TonyTheTiger]

Whether anyone believes or not I personally think finasteride or dht effects male sexual functioning. Some men I guess most dont get noticeable sexual sides but that doesnt mean something doesnt happen to you that you cant feel or notice. I think for some reason dht is tied together with sexual function to some degree.

I am more worried about deformed sperms. Cause I wanna have kids later on.

 

[docj077]

Whether anyone believes or not I personally think finasteride or dht effects male sexual functioning. Some men I guess most dont get noticeable sexual sides but that doesnt mean something doesnt happen to you that you cant feel or notice. I think for some reason dht is tied together with sexual function to some degree.

I am more worried about deformed sperms. Cause I wanna have kids later on.

Why do you think that a drug like finasteride would cause permanent sperm dysfunction? Finasteride does not act at the gene level in that it doesn't permanently alter genetic machinery. If the effects at the gene level are not permanent, then the effects on sperm production are not permanent, as well. These guys all had problems before they went on finasteride.

 

[michael barry]

Doctor,

Ive been around hairloss sites for a while now, and I can tell you this: Every so often "newbies" with a few dozen posts come into discussion forums and start posting info about the supposed "dangers" of finasteride. I openly wonder if they are all the same hack that works for male pattern baldness-research.org who wants to get everyone on herbals that they sell through their buyers club and similar arrangements with others. If you scare people off finasteride, they will try multiple things like soy isoflavones, 'root food' concoctions , saw palmetto and sterol blends, and other herbal prostate pills, etc. It almost happens in "cycles".


Right now in the general discussion forum, there is a guy floating that "cooked fat" theory again. Also a newbie. It makes one wonder.....................


Hairloss discussion sites really never haved proved nearly as fruitful as they should have been . I had hoped upon finding these sites they would be filled with men who tested various topicals and internals on themselves and posted pictures of their results or told others of their results. It just hasn't been the case. What one gets are scammers, mentally deranged, childish people who want a 'cure' just handed to them, and people who read absolutely nothing but post anyway, and a fe people who push private baldness theories that they just cannot let go of. Its been a dissapointment.

The highest level of discussion Ive ever witnessed as far as effective working treatment regimines were back when Dave001, matt500 (another site), Bryan, and a few others were at it in the early 00's. "Legendary" posters like the Almighty God of Hairloss and others who really researched the literature and knew their stuff fell off posting a few years ago now. Its not as good as it used to be.

By the way..............Im sure you remember the "shampoo guys". Hairsite found out they all (4) used the same IP address. It was the same guy. A real nutter. Thats what we are dealing with.................

 

[TonyTheTiger]

Doctor,

Ive been around hairloss sites for a while now, and I can tell you this: Every so often "newbies" with a few dozen posts come into discussion forums and start posting info about the supposed "dangers" of finasteride. I openly wonder if they are all the same hack that works for male pattern baldness-research.org who wants to get everyone on herbals that they sell through their buyers club and similar arrangements with others. If you scare people off finasteride, they will try multiple things like soy isoflavones, 'root food' concoctions , saw palmetto and sterol blends, and other herbal prostate pills, etc. It almost happens in "cycles".


Right now in the general discussion forum, there is a guy floating that "cooked fat" theory again. Also a newbie. It makes one wonder.....................


Hairloss discussion sites really never haved proved nearly as fruitful as they should have been . I had hoped upon finding these sites they would be filled with men who tested various topicals and internals on themselves and posted pictures of their results or told others of their results. It just hasn't been the case. What one gets are scammers, mentally deranged, childish people who want a 'cure' just handed to them, and people who read absolutely nothing but post anyway, and a fe people who push private baldness theories that they just cannot let go of. Its been a dissapointment.

The highest level of discussion Ive ever witnessed as far as effective working treatment regimines were back when Dave001, matt500 (another site), Bryan, and a few others were at it in the early 00's. "Legendary" posters like the Almighty God of Hairloss and others who really researched the literature and knew their stuff fell off posting a few years ago now. Its not as good as it used to be.

By the way..............Im sure you remember the "shampoo guys". Hairsite found out they all (4) used the same IP address. It was the same guy. A real nutter. Thats what we are dealing with.................

Ya some guy on another board tried to tell me to take saw palmetto but then I heard the sides from saw palmetto are unrecorded. It is not fda approved either.

I am so scared of reading these posts especially about this sperm stuff.

 

[harold]

Michael if you are referring to me I am no newbie. As I said I have been on finasteride for about 6 years, was at alt.baldspot before Ernie totally destroyed it as a usable group and was interested in this before dutasteride was on the scene. I have seen the hopes for "a cure" rise and fall and people who were dead certain that in 5 years from "now" we would all be using hair multiplication and wouldn't have to worry about this sh*t. Nothing I have posted in this thread has been inflammatory or sensational. Just more information for people to do with as they see fit.
hh

 

[Armando Jose]

Ah,... Mr. Primeau,

What good times!!

I also remember angry discussion between Ertel, Farrel and even Dave, Proctor, Bryan....

Armando

 

[harold]

....That guy was a fricking robot...."Farrell the snake oil salesman"....replied to everything.
I think he was listed as one of Usenets top 10 worst trolls.
hh

 

[dimitri]

I got the dilemma too, am worried about birth defects to be honest if I take the proscar, not started a family yet, and have not seen conclusive stats to see if a pattern exists to correlate with use of the drug by fathers to be