stopped Avodart

CCS

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just after I got of the shower and applied some topicals, i thought my hair looked thick, and was pleased with my regimen. Just 15 minutes later, I looked at it again, and i guess from a different angle or something but it looked very thin. So I popped another 1.25mg finasteride in my mouth and decided to do this daily until i get the drugs tested.

Just shows the importance of pictures.
 

ecs

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just my 2 cents
I started Avodart with a dose of 4 times a week, had a bit shedding of short hairs about 2 weeks from day zero, and the shedding has gradually subsided, I am at my two months mark now, nothing big happened and I have just changed my dose from 4 to 3 times a week

I am not a fresh starter though, I switched from finasteride to Avodart, and I did have a very bad shedding (all kinds of hairs damn it) when I first started with finasteride

You may want to lower your dose instead of quitting it all at once, most likely the hair you lost in shedding period will come back in 6 months to a year

Good Luck Pal
 

MPBWarrior

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Also remember the importance of androgen blockers in the hair line when taking dutasteride (something u don't have to worry about so much when on finasteride)
 
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MPBWarrior said:
Also remember the importance of androgen blockers in the hair line when taking dutasteride (something u don't have to worry about so much when on finasteride)

uh what? you don't have to add topical androgen blockers while taking dutasteride.
 
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MPBWarrior said:
Also remember the importance of androgen blockers in the hair line when taking dutasteride (something u don't have to worry about so much when on finasteride)

does anyone else here agree with this statement? im on dutasteride so i'm curious.
 

Felk

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I presume he's referring to the 104% rise in testosterone levels from taking dutasteride. Other androgens are also likely to be a factor in hair loss.
 

MPBWarrior

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yes, that's exactly what i'm refering to. testosterone is an androgen that causes hair loss. the difference is that DHT is something like 20 or 30 times stronger so everyone just talks about DHT. but when u have a significant new amount of testosterone going around in your scalp, it wouldn't hurt to apply a topical anti-androgen.
 
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ill see how it goes first after a year. then if i see loss i'll add spironolactone.

why'd you only mention the hair line to apply the anti androgen to male pattern baldness?
 
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Felk said:
I presume he's referring to the 104% rise in testosterone levels from taking dutasteride. Other androgens are also likely to be a factor in hair loss.

didn't rittmaster conclude from this that almost all the dht in the scalp is type I and not type II? doesn't that contradict a lot of the stuff posted on this site?
 

Bryan

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JayMan said:
didn't rittmaster conclude from this that almost all the dht in the scalp is type I and not type II? doesn't that contradict a lot of the stuff posted on this site?

How does it contradict anything? I would imagine that most of the DHT in the scalp does come from the type I enzyme, but "the scalp" contains other structures than just hair follicles. It also contains sebaceous glands (which are rich in type I) and sweat glands. But we aren't that interested in sebaceous glands and sweat glands (except for Armando! :D ), we're interested in hair follicles. In my opinion, the type II enzyme has been shown to be the most important factor in hair follicle dermal papillae.

Bryan
 

Fallout Boy

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Bryan said:
JayMan said:
didn't rittmaster conclude from this that almost all the dht in the scalp is type I and not type II? doesn't that contradict a lot of the stuff posted on this site?

How does it contradict anything? I would imagine that most of the DHT in the scalp does come from the type I enzyme, but "the scalp" contains other structures than just hair follicles. It also contains sebaceous glands (which are rich in type I) and sweat glands. But we aren't that interested in sebaceous glands and sweat glands (except for Armando! :D ), we're interested in hair follicles. In my opinion, the type II enzyme has been shown to be the most important factor in hair follicle dermal papillae.

Bryan

What exactly do you mean here Bryan? Type II is an important factor as in it's bad for your hair follicle?? And what does FInasteride deal with...Type II?

If Finasteride inhibits Type II how much of an influence do you think type I has on hair?
 

CCS

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DHT fron type I can leak into follicles, but it is responsible for probably only 10% of the DHT in the follicle. Most of the damage is done by the DHT made in the follicle by type II. Finasteride treats this, but only knocks out 90% at 5mg, and less at 1mg. Dutasteride knocks out over 98.5% at 0.5mg/day, and 95% at 3 per week.
 

powersam

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look the most simple proof is that merck made a specific type 1 inhibitor and tested it. It had absolutely no effect on hair loss whatsoever. would this not mean that type 1 really isnt involved? and we dont really care about whats in the scalp as much as whats in the follicle itself.
 

Felk

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powersam said:
look the most simple proof is that merck made a specific type 1 inhibitor and tested it. It had absolutely no effect on hair loss whatsoever. would this not mean that type 1 really isnt involved? and we dont really care about whats in the scalp as much as whats in the follicle itself.

That is one compelling argument about the importance of type 2 over type 1, but luckily not the only one, because MK also had no effect on acne, and this is certainly a problem that is believed to be related to type 1 5AR. This result was very unexpected, and the scientists can't really explain it. If there was no other evidence, one might be wary that MK's lack of effect on hair loss was also an unexplainable outcome.
 

powersam

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hmm i didnt know about that part. but isnt acne caused by a whole host of things? bacteria in the pores for instance.
 
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