It's a very good point that OC459 and TM30089 have had no impact on hairloss.
With that said, I had some thinking in the car as to how DHT might not be the whole story. Behold some intellectual masturbation coming up
It relates to female pattern hairloss -- it doesn't respond to finasteride, at all. Interestingly, though it doesn't look like standard male pattern baldness with the receding hairline and temple and crown, it does resemble diffuse thinning, since that's what female pattern hairloss: the hair is distributed in the same manner, but more diffuse. On the other hand, I've seen photos on this forum of people with receding hairlines, but not diffuse hairloss.
I think this hints (demonstrates?) at two separate mechanisms, where the androgenic mechanism only hits men, and can accelerate diffuse hairloss.
You once wrote that you believe that somebody on both dutasteride and RU58851 cannot lose hair (pretty sure that was you). Yet, based on the clinical trials of women on finasteride, that might not apply to women with diffuse thinning. So something else might not work, I'm not necessarily pointing to DP2 antagonists.