switching from finasteride

hair today gone tomorrow

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Re: dutasteride

JayMan said:
Timi said:
Pondle

to
JayMan, Roki, Slartibartfast, Aplunk, Oni, CCS... etc etc.

Yes i read this but i see no Success Picture! why??
JayMan Ok but he says he is a very Good minoxidil Responder

Many takes dutasteride and have full Hair and sell that for success
Picture from NW6 to NW2 would be Good



Timi

Man I hope Timi is psychic. He keeps telling me that I say I'm a very good minoxidil responder. I've never used it. Hopefully Timi is predicting the future.

HTGT I told you what I would do on the first page, if you wanted, so you did get an answer.

JayMan said:
i took finasteride along with dutasteride for two weeks to ease into it but i don't think its really necessary. maybe you should just do what i did though.

yah i got your opinion...but id like some others...preferably mike barry, bryan,?
 

hair today gone tomorrow

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anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to finasteride than dutasteride...i guess it depends on your genotype? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?
 
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hair today gone tomorrow said:
anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?
 

hair today gone tomorrow

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JayMan said:
hair today gone tomorrow said:
anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?

how do i know im a better responder?? i may not respond to dutasteride at all.
 
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hair today gone tomorrow said:
JayMan said:
[quote="hair today gone tomorrow":c2894]anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?

how do i know im a better responder?? i may not respond to dutasteride at all.[/quote:c2894]

i would imagine that most people will respond better to dutasteride due to the increased inhibition etc etc
 

hair today gone tomorrow

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JayMan said:
hair today gone tomorrow said:
JayMan said:
[quote="hair today gone tomorrow":b8212]anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?

how do i know im a better responder?? i may not respond to dutasteride at all.

i would imagine that most people will respond better to dutasteride due to the increased inhibition etc etc[/quote:b8212]

etc,etc? i dunno this dude is a pretty knowlegeable guy..he says some guys have better response to finasteride than dutasteride...something about dependong on your genotype...i dunno..

I remember reading a post of his..where he says he knows a few guys that have seriously regretting switch from finasteride to dutasteride..

bryan what do you think?
 
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hair today gone tomorrow said:
JayMan said:
[quote="hair today gone tomorrow":5a903]
JayMan said:
[quote="hair today gone tomorrow":5a903]anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?

how do i know im a better responder?? i may not respond to dutasteride at all.

i would imagine that most people will respond better to dutasteride due to the increased inhibition etc etc[/quote:5a903]

etc,etc? i dunno this dude is a pretty knowlegeable guy..he says some guys have better response to finasteride than dutasteride...something about dependong on your genotype...im dunno..[/quote:5a903]

ok well you said this:

hair today gone tomorrow said:
nyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride

you said that like it was amazing that someone would be a better responder to dutasteride than to finasteride. i don't get it. what are you asking me?
 

hair today gone tomorrow

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JayMan said:
hair today gone tomorrow said:
JayMan said:
[quote="hair today gone tomorrow":a5f16]
JayMan said:
[quote="hair today gone tomorrow":a5f16]anyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride...i guess it depends on your genome? Im not to sure but ive read that..Peter Mac on hlh has brought it up many times...maybe its better to stick to a dutasteride/finasteride comb?

if you're a better responder to dutasteride than finasteride then what does that have to do with sticking with a dutasteride/finasteride combo?

how do i know im a better responder?? i may not respond to dutasteride at all.

i would imagine that most people will respond better to dutasteride due to the increased inhibition etc etc

etc,etc? i dunno this dude is a pretty knowlegeable guy..he says some guys have better response to finasteride than dutasteride...something about dependong on your genotype...im dunno..[/quote:a5f16]

ok well you said this:

hair today gone tomorrow said:
nyway...jayman, ive read mostly on hlh...that its possible to be a better responder to dutasteride than to finasteride

you said that like it was amazing that someone would be a better responder to dutasteride than to finasteride. i don't get it. what are you asking me?[/quote:a5f16]

my bad... i edited my post...i meant the other way around...sorry for the confusion.
 
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well i don't know what to think. the thing for me is i feel like if i try to go back to finasteride and give it 6 months, i may lose my gains that dutasteride gave me. i don't really think finasteride could give me much more than dutasteride gave me, and in all likelihood would make me lose hair that i've gained. so im not gonna try it.

has finasteride actually grown back hair for you or just maintenance? if finasteride gave you some solid regrowth i'd stick with it, but if it hasn't, i don't think you have anything to lose by going to dutasteride because it should give you at least maintenance too, and maybe more.
 

hair today gone tomorrow

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JayMan said:
well i don't know what to think. the thing for me is i feel like if i try to go back to finasteride and give it 6 months, i may lose my gains that dutasteride gave me. i don't really think finasteride could give me much more than dutasteride gave me, and in all likelihood would make me lose hair that i've gained. so im not gonna try it.

has finasteride actually grown back hair for you or just maintenance? if finasteride gave you some solid regrowth i'd stick with it, but if it hasn't, i don't think you have anything to lose by going to dutasteride because it should give you at least maintenance too, and maybe more.

i wouldnt save ive regrown on finasteride..prob just maintenance..maybe something thickening in the vertex...hairline hasnt really changed...it still looks a little thin when wet..but its fine when dry...i can still spike it up and it looks fine dry...

Im scared of switching to dutasteride and then not responding at all to it...thats why im considering a finasteride/dutasteride combo...maybe im nuts/paranoid..lol.
 
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hair today gone tomorrow said:
JayMan said:
well i don't know what to think. the thing for me is i feel like if i try to go back to finasteride and give it 6 months, i may lose my gains that dutasteride gave me. i don't really think finasteride could give me much more than dutasteride gave me, and in all likelihood would make me lose hair that i've gained. so im not gonna try it.

has finasteride actually grown back hair for you or just maintenance? if finasteride gave you some solid regrowth i'd stick with it, but if it hasn't, i don't think you have anything to lose by going to dutasteride because it should give you at least maintenance too, and maybe more.

i wouldnt save ive regrown on finasteride..prob just maintenance..maybe something thickening in the vertex...hairline hasnt really changed...it still looks a little thin when wet..but its fine when dry...i can still spike it up and it looks fine dry...

Im scared of switching to dutasteride and then not responding at all to it...thats why im considering a finasteride/dutasteride combo...maybe im nuts/paranoid..lol.

what is a finasteride dutasteride combo going to do for you that taking dutasteride every day or every other day won't?
 
T

Timi

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Re: dutasteride

JayMan said:
Timi said:
Pondle

to
JayMan, Roki, Slartibartfast, Aplunk, Oni, CCS... etc etc.

Yes i read this but i see no Success Picture! why??
JayMan Ok but he says he is a very Good minoxidil Responder

Many takes dutasteride and have full Hair and sell that for success
Picture from NW6 to NW2 would be Good



Timi

Man I hope Timi is psychic. He keeps telling me that I say I'm a very good minoxidil responder. I've never used it. Hopefully Timi is predicting the future.

HTGT I told you what I would do on the first page, if you wanted, so you did get an answer.

JayMan said:
i took finasteride along with dutasteride for two weeks to ease into it but i don't think its really necessary. maybe you should just do what i did though.


Oh was wrong
Skyline is a Good minoxidil Responder and not JayMan

Sorry

Timi
 

hair today gone tomorrow

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JayMan said:
hair today gone tomorrow said:
JayMan said:
well i don't know what to think. the thing for me is i feel like if i try to go back to finasteride and give it 6 months, i may lose my gains that dutasteride gave me. i don't really think finasteride could give me much more than dutasteride gave me, and in all likelihood would make me lose hair that i've gained. so im not gonna try it.

has finasteride actually grown back hair for you or just maintenance? if finasteride gave you some solid regrowth i'd stick with it, but if it hasn't, i don't think you have anything to lose by going to dutasteride because it should give you at least maintenance too, and maybe more.

i wouldnt save ive regrown on finasteride..prob just maintenance..maybe something thickening in the vertex...hairline hasnt really changed...it still looks a little thin when wet..but its fine when dry...i can still spike it up and it looks fine dry...

Im scared of switching to dutasteride and then not responding at all to it...thats why im considering a finasteride/dutasteride combo...maybe im nuts/paranoid..lol.

what is a finasteride dutasteride combo going to do for you that taking dutasteride every day or every other day won't?


i just told you man...supposedly some people respond better to finasteride than dutasteride....heck some dont respond to dutasteride at all but respond to finasteride...

I have responded some to finasteride...but if i want to try dutasteride it my be wise to combo it with finasteride just IN CASE i dont respond to dutasteride.
 

Pondle

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There are so many fake batches doing the rounds on internet pharmacies I think it's difficult to conclude whether anyone responds to finasteride but not dutasteride. Given that both drugs work in exactly the same way, i.e. binding to 5AR, and that dutasteride is both absolutely superior to finasteride (and shows less variation in DHT suppression between subjects - see chart) I find it difficult to conclude that a real batch could ever be worse.

DutDHTsuppression.gif
 

Bryan

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Pondle said:
...dutasteride is both absolutely superior to finasteride (and shows less variation in DHT suppression between subjects - see chart)

The last part of that sentence is what always bothers me a little. Looking at that chart, it seems to me that the variation in DHT suppression between subjects with dutasteride is the same as with finasteride.
 

Pondle

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Bryan said:
The last part of that sentence is what always bothers me a little. Looking at that chart, it seems to me that the variation in DHT suppression between subjects with dutasteride is the same as with finasteride.

At the 0.5mg dose, the variation seems almost minimal.
 

Bryan

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Sure, but you would expect the variation to be very minimal, if you go all the way to near the end of the curve! In other words, if you were to adjust the dose to achieve something like 99.99% DHT suppression, wouldn't you expect the variation to be something almost undetectable, like maybe something between 99.9% and 99.999%? :wink:

To compare two different drugs to see how their variations compare, you'd have to compare them under the same test conditions; specifically, under conditions of equal DHT suppression. Ideally, you would adjust the doses of the two drugs so that both achieve an average suppression of 50%, and THEN you see how much variation you get with them. That's the only logical way to do it.
 

Pondle

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I understand, but I'm comparing two products which are competitors in a single market - Proscar and Avodart - at their respective recommended dose. When we look at like this, then in Avodart patients the mean suppression is higher and the range is smaller compared to Proscar patients. I accept that the higher end of the range could never exceed 100%, and that the closer we get to the end of the curve the smaller the likely range.
 

Bryan

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Yes. So it doesn't even make sense to talk about "variation" in that context. You're comparing apples and oranges.
 
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