The Cb (breezula [clascoterone]) Community Thread

[adamhs]

I bet if the HPA thing was not mentioned nobody would experience those sides. i want to know how many would report having an itchy *** if casiopea mentioned that as a side in the study

Nah the sides were real, it's incredibly obvious because you feel physically sick, it's not like most AA sides.

I'd be surprised if most of the issues in this thread would occur from using pure CB though. Kane's known for shipping impure CB, and he runs all the major suppliers (anagen, science.bio, chemyo). One guy on HairLossTalk.com used Wuhan CB and was told his blood had heavy metals in it after he had to go to the ER after using it, so wouldn't surprise me at all if Kane CB caused the sides in here.

What we need is someone with tested CB, using a proper vehicle at a normal dose to report sides. But it's going to be tough to find that.

 

[scientist_0005]

HairLossTalk.com used Wuhan CB and was told his blood had heavy metals in it after he had to go to the ER after using it

jesus f*****g christ..

 

[telogen]

One guy on HairLossTalk.com used Wuhan CB and was told his blood had heavy metals in it after he had to go to the ER after using it.

Any more info on this?

 

[Fgsfds]

Hola, alguien compro cb de alibaba? En biohorlden biotech

shut up

 

[adamhs]

I used some CB recently bought and tested some CB, 7.5%. I used barely any, only a few drops, and had heart palpitations and chest pain for 6 hours following, and a reduction in scalp itch. Am I just extremely sensitive to it or something? It takes around 8 hours for the molecule to degrade into its harmless metabolite. I might try a 1% solution at some point, but not any time soon.

 

[clarence-forgotpassword]

Amazing no-one has noted this is out already, although it's for acne. It's a cream that doesn't go systemic, a stronger application is being developed for androgenetic alopecia. Suppose I marched into a doctor's office and told them I wanted to try the acne cream for hair loss...?

 

[John Difool]

At 10 times less the dosage needed for hair follicle? I think you would sound really stupid.

 

[clarence-forgotpassword]

At 10 times less the dosage needed for hair follicle? I think you would sound really stupid.

So... Now that it's out, it's easier for some lab to make a stronger version of it?

 

[jamesbooker1975]

Only person I recall having results from CB is El Duterino and his hair loss is not aggressive.

Jesus. HOW THE HELL buying homemade stuff on blackmarket have any validation with real product ?! Stop the false idea that you are getting the right thing .

 

[jamesbooker1975]

So... Now that it's out, it's easier for some lab to make a stronger version of it?

No, since it have a patent. Any ways, wonder for how long that patent last since it look like forever since the first time I read about CB , at least 10 years already passed.

 

[John Difool]

I guess so.

 

[BigBadBaldie]

Only person I recall having results from CB is El Duterino and his hair loss is not aggressive.

Well hardly anyone on here has tried it - an even smaller percentage are probably using an adequate amount and formulating it in the correct manner. Most people on here just dump whatever powder into minoxidil and expect it to work…

 

[John Difool]

I did CB for 2 months. exactly at the patent dosage with same vehicle . Cost was very high. but that's not important. I was ready to pay for anything that could work. 7.5% bid was my dosage at 2ml. Results were disappointing. I lost ground on RU gains. I went back to RU after 8 weeks. CB is still in my freezer.

 

[BigBadBaldie]

I did CB for 2 months. exactly at the patent dosage with same vehicle . Cost was very high. but that's not important. I was ready to pay for anything that could work. 7.5% bid was my dosage at 2ml. Results were disappointing. I lost ground on RU gains. I went back to RU after 8 weeks. CB is still in my freezer.

That sucks. I’ve seen you have a lot of experience with hairloss stuff. I saw in the studies around 1/3rd of people didn’t respond to CB. It’s disappointing considering the high cost.
Having said that I stand by what I said in my previous point. I think lots of people in this forum aren’t using stuff appropriately. They just dump stuff in minoxidil and hope for the best.

 

[John Difool]

Hands on experience for the last 3 years only. I don't try to save a penny by using mice dosage vs human dosage. I try to go by the patent, trials and other things that bring the tests closer to what the intent is. As soon as you try to optimize and cut corners at the beginning, it is a waste and as you said, people conclude it's not working. Which doesn't bring any advantages trying it in the first place.

if you can't stand the heat, get out of the kitchen

 

[Mr White]

I've lost all interest in Breezula. I'm now focused on Kintor's new topical treatment.

 

[BigBadBaldie]

I've lost all interest in Breezula. I'm now focused on Kintor's new topical treatment.

I don’t think anyone is hyped for Breezula - I’d be happy if it got approved soon though as it’s just another option in the very limited arsenal of hairloss treatments with any efficacy.

 

[badnewsbearer]

Hands on experience for the last 3 years only. I don't try to save a penny by using mice dosage vs human dosage. I try to go by the patent, trials and other things that bring the tests closer to what the intent is. As soon as you try to optimize and cut corners at the beginning, it is a waste and as you said, people conclude it's not working. Which doesn't bring any advantages trying it in the first place.

if you can't stand the heat, get out of the kitchen

what will be the affinity and potency of pyralutamide compared to RU? is it stronger or weaker?

 

[BigBadBaldie]

what will be the affinity and potency of pyralutamide compared to RU? is it stronger or weaker?

It’s significantly more potent than RU - but we still have yet to see studies proving it’s effectiveness or anecdotes from people experimenting with it. Binding affinity isn’t the only thing that matters.

 

[badnewsbearer]

It’s significantly more potent than RU - but we still have yet to see studies proving it’s effectiveness or anecdotes from people experimenting with it. Binding affinity isn’t the only thing that matters.

so what else matters? with agonists there is affinity(how much force attraction is there between the ligand and the receptor) and efficiency(with the induced conformational changes of the ligand receptor complex how many of the receptor related genes are going to get transcriped, how kuch of the receptor is activated), this combined is potency of the agonist. with an antagonist it seems to me that the only important thing is binding affinity and complete imabikity of the complex to bind to a promotor element.

concentration is also important of course. if i recall correctly RU is delivered in a 5% concentration? is pyralutamide the same concentration?

i also wonder since many have reported sexual sides on RU why would this not happen on pyr if the affinity is higher and the concentration is the same?