The Group Buy to End All Group Buys: Twist1 Inhibitor

Hairful

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If this sh*t works and the GB guys do not tell us on the forum, they're straight up evil.
They know as no other how depressive some people here get trough their hairloss and then not telling your fellow balders is such a stab in the back
Lol, if this becomes successful don’t worry. They will tell it and try to sell more of it, easy money.

You don’t want it to be a one time cure because that would mean twist1 is turned off forever, and you don’t want that. So it will be a continuous thing. Given quinolones are mostly antibiotics/antimalarials which this ADQ seems to be a derivative of from my little research on it and they’re notorious for joint damage and qT prolongation is shared among all derivatives/generation, ADQ might itself possess those properties too. That’s beside the damage twist1 inhibition might do.

I suspect the person arranging this knows all this and the goal is to make as much money off it as possible, hence why it’s kept hidden and the FOMO BS. Or it could just be placebo.
 

RagnarLothbrok

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Wtf you talking about, no one is earning anything from any sale, the only benefit is trying a new compound and share info with your peers. It all goes to a Wuhan lab and each user pays directly to them with 0 middlemen. You think there is some conspiracy to make some random chinese lab millionare? ... in fact the gb is closed now instead of taking more orders. This is flat earther level paranoia
 

Kagaho

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Wtf you talking about, no one is earning anything from any sale, the only benefit is trying a new compound and share info with your peers. It all goes to a Wuhan lab and each user pays directly to them with 0 middlemen. You think there is some conspiracy to make some random chinese lab millionare? ... in fact the gb is closed now instead of taking more orders. This is flat earther level paranoia

Dude, youre obviously new to this group buy game. Maybe those promoting it are not making money but it almost never work the way they say. Its sad but this Twist stuff will fade away like all the others experimental compounds they tried, almost guaranteed.
 

RagnarLothbrok

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Dude, youre obviously new to this group buy game. Maybe those promoting it are not making money but it almost never work the way they say. Its sad but this Twist stuff will fade away like all the others experimental compounds they tried, almost guaranteed.
This is like my 8th group buy, and no one is putting you a gun in your head to try any molecule. Yes, most mollecules fail just like most hair loss research trials fail. Genius observation.
 

Redgate

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It's a good thing that sections about a particular compound are only available to those who buy the compound because the discord server is sometimes an overall reflection of hairlosstalk.com (incel talk, repeated questions, suicidal thoughts over hair, people who don't know what they're talking about) and it needs hairlosstalk.com-free zones.

You are not entitled to anyone's results and if someone wants to make them public they'll make a thread or post here about them.
 

Hairful

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Wtf you talking about, no one is earning anything from any sale, the only benefit is trying a new compound and share info with your peers. It all goes to a Wuhan lab and each user pays directly to them with 0 middlemen. You think there is some conspiracy to make some random chinese lab millionare? ... in fact the gb is closed now instead of taking more orders. This is flat earther level paranoia

Just hella sus behaviour to hide these results and require 175$ paywall

If research was the goal, the results would be public for everyone to see
 

Hairful

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It's a good thing that sections about a particular compound are only available to those who buy the compound because the discord server is sometimes an overall reflection of hairlosstalk.com (incel talk, repeated questions, suicidal thoughts over hair, people who don't know what they're talking about) and it needs hairlosstalk.com-free zones.

You are not entitled to anyone's results and if someone wants to make them public they'll make a thread or post here about them.

man just shut the f*** up, like seriously

That discord was full of low IQ retarded fucks worse theories than this forum gets blamed for, literally one guy was claiming that eunuchs don’t bald and his proof was some photos of an old man supposedly eunuch and balding

That sort of sh*t will get laughed at if posted here publicly, but in the discord with a bunch of ignorants doing Internet personality worship like you do, he was getting away with it. That’s not unfortunately the only BS

This I imagine is why the results are private away from prying objective eyes, the people who spent money are invested and will see results just from sheer placebo effect and the the guy arranging it can be the judge lol, laughable sh*t.

HairLossTalk.com is pretty good despite the retardedness, if it became a closed cult echo chamber then it would downgrade really quickly too.
 

Janko

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With the rhetoric and behavior you are presenting here, you are making yourself great example, why the GBs should be closed only for people that are participating.
 

Ollie

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Just hella sus behaviour to hide these results and require 175$ paywall

If research was the goal, the results would be public for everyone to see

Mate, you're making out like you're paying $175 to just be part of a discord. As soon as a GB opens up to the HairLossTalk.com community it gets flooded with pure stupidy - which is exactly why the viewership on the discord is limited only to those who have actually paid for the treatment.

Like with any other GB if someone has results they then get shared here on HairLossTalk.com.

HairLossTalk.com is pretty good despite the retardedness

Its pretty good because the handful of people from the GB's who actually research productively bring that research into the forum for discussion.
 

Redgate

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Just hella sus behaviour to hide these results and require 175$ paywall

If research was the goal, the results would be public for everyone to see
There's no paywall now. Orders are closed.
If someone wants to post their results, they will. Why do you have a problem with this? Also there hasn't been a single GB where the results weren't made known here.
That discord was full of low IQ retarded fucks worse theories than this forum gets blamed for
Exactly, therefore some sections are reserved for ultra high IQ patricians.
literally one guy was claiming that eunuchs don’t bald and his proof was some photos of an old man supposedly eunuch and balding

That sort of sh*t will get laughed at if posted here publicly, but in the discord with a bunch of ignorants doing Internet personality worship like you do, he was getting away with it. That’s not unfortunately the only BS
What's the problem? That someone is going to see that message and chop of his balls? Wouldn't be the first time
 

Hairful

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With the rhetoric and behavior you are presenting here, you are making yourself great example, why the GBs should be closed only for people that are participating.
Dude stop, if you sucked his *** anymore, you would reach his mouth at this rate.

I rest my case, the way I got attacked earlier for presenting a differing opinion and now for calling out the discord for what it is - paywall - simply shows the sus behaviour. I am more convinced now you suckers are getting crushed rocks given how random ficks are crawling out to defend the paywall. Nobody likes paywall and nobody likes knowledge being hidden either so you’re sus af

Hairlosstalk is bad, blah blah but it’s good for recruiting people and earning some cashish, am I right? Hehe
 

Redgate

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Dude stop, if you sucked his *** anymore, you would reach his mouth at this rate.

I rest my case, the way I got attacked earlier for presenting a differing opinion and now for calling out the discord for what it is - paywall - simply shows the sus behaviour. I am more convinced now you suckers are getting crushed rocks given how random ficks are crawling out to defend the paywall. Nobody likes paywall and nobody likes knowledge being hidden either so you’re sus af

Hairlosstalk is bad, blah blah but it’s good for recruiting people and earning some cashish, am I right? Hehe
lmao stay bald
 

InBeforeTheCure

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ADQ works by promoting Twist1 protein degradation rather than reducing gene expression, so I wonder if it might degrade Twist2 since they are 66% identical. Twist2 mutation does cause hypertrichosis in Barber Say Syndrome.
Just checked - Twist1 expression is 9 times higher than Twist2 in human DP. Could be similar to the mice where Twist2 expression drops a lot in the DP after HF development.
 

Hairful

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You seems new to whole GB thing .
So lets get things in order.
1. This is like the 6-7 GB we doing so far.
2. We dont work with the admin of the group we work with very known lab that make compound for more then 10+ years.
3. The lab set the price based on several factors some of course are the amount we order.
4. For each GB we had the buyers get hidden channel so they can have a better way to have convo with people like them thatuse the drug , so they can share experience and sides ,results etc etc.
5. Since there are many lurkers that dont want take a part in the trail and dont want to spend money we give them the options to see all the general info and vehicle etc
6. Lurkers should not benfit from the “first info “ that testers should .
Thats it. At the end of the trail we usually share in the general channel if its failed or not

Just because you’ve been doing things a certain way and no one objected doesn’t make it right


Imagine being triggered by a group of people doing what they want with their own lives and money. Sounds pretty sad.

Imagine if all the researcher hid their results and only shared with the participants, humanity would have progressed so much….NOT

What is the result of previous GBs? Why did they fail? Even when research is done by proper educated researchers, independent peer reviewers are needed to rule out any bias and without peer review, the study is considered low quality.

You are just involved in a circlejerk pleasuring each other not research.
 

RagnarLothbrok

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Keep warning yourself, people who want to try it will still try it because there's no other way to know if it works or not than by actually taking action.

Its undeniable Twist1 activity is involved in hairloss and people who don't want to wait 10 years doing nothing are moving the straw forward with their own bodies. Maybe this will accelerate finding the cure in future so you better be thankful rather than spiteful about it.

Your main thesis is "people want to make money off shady GB chemicals" but at the same say "its secret and people won't share info if it works" which is contradictory, if it was a sales pitch you would promote it to get more sales and not hide anything.

Just let people do whatever they want and stop this stupid white knight attitude, everyone is a grown adult with their own decisions
 
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Hairful

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Your main thesis is "people want to make money off shady GB chemicals" but at the same say "its secret and people won't share info if it works" which is contradictory, if it was a sales pitch you would promote it to get more sales and not hide anything.

Just let people do whatever they want and stop this stupid white knight attitude, everyone is a grown adult with their own decisions

I don’t think you’re that dense so why are you acting like that. My main thesis is the GB is being super secretive and private and the info isn’t being shared despite recruiting people from here and Reddit calling both places idiotic cesspools - that is what makes it extremely shady and a money earning scheme. If I was selling placebo or crushed rocks, I would want it secret away from prying eyes too, if I was convinced in my theory being sound and the product solid, I would want public.

Cults behave like this, they only recruit gullible people they know will fall prey to whatever they’re selling while being secretive from the rest.

I am only calling out what I see here, I am probably wrong but why behave in such shady manner then?

As for people trying dangerous chemicals, that’s another thing. I was attacked earlier for bringing up studies that point Twist1 isn’t total trash gene and the one study Kevin mentioned wasn’t even brought up by the guy who supposedly knows so much about twist1/ADQ. People are free to do whatever but they should be aware of the dangers and sides as well, all of these lab monkeys don’t even know what ADQ stands for and what the f*** is it.

Again just shady behaviour all around and why the GB is private so only selective info is shared and “trouble makers” might not share other info.
 
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