Topical thyroid hormone as a potential cure?

[Aleksandar]

Topical thyroid hormones to combat hair loss or even initiate new hair growth seems very promising. At least according to this article from 2020:

Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?

Topical hormone therapy with natural or synthetic ligands of nuclear hormone receptors such as glucocorticoids, vitamin D analogues and retinoids has a long and highly successful tradition in dermatology. Yet the dermatological potential of thyroid hormone ...

www.ncbi.nlm.nih.gov

But as always, as long as there is no profit to be made, the farmaceutical industry won’t touch it:

“Given this, from an industry perspective, a hurdle to T4 repurposing in dermatology is securing intellectual property perhaps by way of a novel delivery system or specific vehicle, judged to be patentable or perhaps as a drug–device combination. However, this does not prevent physicians to use T4 preparations off label for selected patients, provided sufficient safety.”

 

[Jakejr]

May not grow hair but might grow a half foot in stature

 

[resu]

That was almost 5 years ago so it should be coming out now right... Also they've been making money with "natural products" for years, snakeoils that do nothing like saw palmetto, there's always a profit, what they don't have is anything that works.

 

[Aleksandar]

That was almost 5 years ago so it should be coming out now right... Also they've been making money with "natural products" for years, snakeoils that do nothing like saw palmetto, there's always a profit, what they don't have is anything that works.

Thyroid hormones are only available by prescription from a doctor. So this not a ‘natural’ product. And it’s not ‘out’ because the farmaceutical companies see no profit in it. If one of them were to develop a topical formula that works, ofher companies could just copy it. So our only hope is that someone with access to these hormones developes it by themselves.

How ironic would it be if the ‘solution’ would be under our noses al this time.

 

[BaldAsshole]

It doesn't work. At least for me. I have been crushing L-Thyroxine tablets in my shampoo for years.

 

[Get my hair back]

Shampoo is a very weak conductor. Not to mention that the molecular weight of thyroxine is 798.86. So you've been doing nonsense for several years.

 

[BaldAsshole]

Shampoo is a very weak conductor. Not to mention that the molecular weight of thyroxine is 798.86. So you've been doing nonsense for several years.

It is 776,87 g/mol for T4 and 650,9776 g/mol for T3, I use both. Being the limit allegedly 500. But I remember reading that you can go higher with warm water.

In any case, I also take them orally. Without any improvement in my hair.

 

[Hazelboy98]

Thyroid hormones are only available by prescription from a doctor. So this not a ‘natural’ product. And it’s not ‘out’ because the farmaceutical companies see no profit in it. If one of them were to develop a topical formula that works, ofher companies could just copy it. So our only hope is that someone with access to these hormones developes it by themselves.

How ironic would it be if the ‘solution’ would be under our noses al this time.

I'm so annoyed by these conspiracy theorists who think the cure to hairloss was this simple the whole time "but the big pharma won't let it out because money!". Finasteride is off patent and is incredibly cheap and most men are too scared to even touch it, whoever comes out with an alternative medication let alone one stronger than finasteride will make so much f*****g money it's not even funny. The solution was not "under our noses the whole time" because the solution is really f*****g hard to find, there are so many genes involved in hairloss so even using something as advanced as CRISPR to figure out a cure is gonna take a long *** time. The ignorance of your post pisses me off like nothing else, it's actually audacious that you've been here since 2016 and you still have these thoughts about hairloss

 

[BaldAsshole]

I'm so annoyed by these conspiracy theorists who think the cure to hairloss was this simple the whole time "but the big pharma won't let it out because money!". Finasteride is off patent and is incredibly cheap and most men are too scared to even touch it, whoever comes out with an alternative medication let alone one stronger than finasteride will make so much f*****g money it's not even funny. The solution was not "under our noses the whole time" because the solution is really f*****g hard to find, there are so many genes involved in hairloss so even using something as advanced as CRISPR to figure out a cure is gonna take a long *** time. The ignorance of your post pisses me off like nothing else, it's actually audacious that you've been here since 2016 and you still have these thoughts about hairloss

I know you are frustrated. We are all. But I don't think there is any need to take our frustration into this user. He is trying to be helpful, that's all. He is not responsible for our shared predicament.