Trying Sildenafil 0.5% solution with Minoxidil 5% and Cetirizine 0.3%

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Hi, not sure into which forum I should put this thread but since this is virtually not possible to find on the internet due to a sheer number of spammy links about sildenafil, I consider it a "new research".

After reading this patent from 2002 I have decided to get into action with \/iagra and I am going to make my own study with me as guinea pig: sildenafil (\/iagra) came today and I have made a 0.5% alcohol+water solution and applied it to my skull. (there was a study where they used 1% solution on reproductive organs to treat erectile dysfunction so I think I am not very far from the actual correct formula).

I will see if I get some good results within 2-3 months. Hope not to get too many boners. But if it doesn't work in 1 month (no visible difference on that lanugo babyhair), I will double the concentration of sildenafil to 1%. Trying to get the synergistic effect of minoxidil + sildenafil with the anti-androgenic effects of daily Nizoral shampoo (ketoconazole) and Cetirizine catching the androgen-related mess downstream. Along with potent antioxidants, just check my daily regime.

 

[supermusic]

 

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preparing the topical solution and first experiences with Sildenafil

Sildenafil came in form of 7 "jelly" fruity packets (it's actually not jello-like, it's a gel - like a shampoo). It immediately seemed ideal for making a solution like I needed. One packet contained 100mg of the active ingredient. This means if I dissolve 1 packet in 19.5g of solvent it would give me 0.5% solution of the stuff. "The stuff" tasted very sweet and bitter at the same time.

As a solvent I used a 60% pure alcohol solution (not denatured). The alcohol should enhance absorption, as described in the study mentioned in the 1st post of this thread. I however did not want to make a rubbing gel like they made in the study, I wanted a solution which would quickly dry on top of the scalp like minoxidil solution does.

Dissolving the "jelly" in the alcohol-water solution was very easy. However there was some kind of substance in the jelly which reacted either with water or alcohol and created small white gummy shards, which were easy to pick with fingers or with spoon. Rest of the substance dissolved easily, I suspect the synthetic gummy bits coming from some gelous substance unrelated to sildenafil. I ate them and got no priapistic boners so I guess there was zero or very little sildenafil in them.

I carefully put the solution into drops bottle from used coughing drops, trying to get as little gummy bits into the bottle as possible. One drop of the solution tasted very nice on tongue, I imagine this would totally rock on some wild frat party as a recreational get-high-and-fcuk drug. And butt-chugging this stuff would be like beyond awesome, Xander would definitely love it. I mean get this: you butt-chug AND you get a boner at the same time.. unk: Erm.. sorry, I got carried away for a minute there.

Nevertheless, I did put the stuff on my head, right after I washed the hair with nizoral (=ketoconazole) and used minoxidil. The feeling on head was very pleasant, free of any irritation or itching, feeling of cool liquid. I used my fingers to massage it into scalp. Drying is without itchiness. I licked one still wet finger, yep, still very sweet despite previous minoxidil application, so now I have a very sweet hair and skin on my head. Hopefully it's not sugar so it will not be consumed by bacteria or yeasts. Next, once this is dry [as of now] I will apply the watery cetirizine solution. Will report in 24 hours after a few more applications on how the skin tolerates all this.

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Supermusic: haha, you beat me to the 2nd post

 

[Fbalding84]

It might help with blood flow like minoxidil.

 

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So I report after a few weeks. The stuff I made from sildenafil gel lasted for about 2 weeks. Application was pretty much flawless. The substance is usually applied immediately after minoxidil, just wait a minute till minoxidil dries and then apply the drops. In the evening I apply minoxidil after I wash my head with ketoconazole shampoo while it's still damp (should enhance absorption).

The gooey-sweet drops makes hair stick like a hair gel, after it dries up.

There were no side effects discovered during those two weeks. One possible side effect are nicer erections but nothing like priapism or anything, there always has to be a stimulus. Perhaps it's just a placebo effect, it's very difficult to say/quantify. I definitely enjoy any sex and fap sessions these days.

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Forgot to mention immediate tolerance and skin effects: none. Feels fine, almost astringent. Dries quickly. Sometimes I lick my finger after I touch my skin on scalp. It always has sweet-bitter taste. That means the stuff is there and should be working.

I remembered one possible side-effect: after I apply it at night, I usually get quickly very tired which I think means that it lowers blood pressure substantially in conjunction with minoxidil. I recently had pre-high BP for a long time period but ever since I started with minoxidil I have very normal BP.

 

[chemicalbrother]

lol ... I was thinking about using sildenafil topically couple of months ago (regarding bloodflow) - will be interesting to see how u get along.
and you are absolutely right: the term "sildenafil" is just un-googleable (is that a word) due to the 99% spam that term returns.

Important question tho: is this the first time you started using minoxidil too ? What strength and kind (liquid or foam) were you on before ?

Interesting part/conclusion of study:

[FONT=Arial]It is believed that topical minoxidil such as Rogaine[/FONT][SUP]RTM [/SUP][FONT=Arial](commercially available from Pharmacia & Upjohn Inc., Bridgewater, N.J.) without a cGMP-PDES inhibitor such as sildenafil citrate (v****[/FONT][SUP]RTM[/SUP][FONT=Arial], commercially available from Pfizer) results in thin, baby-like, temporary hair, called “lanugo” hair. The present invention will result in good, coarse, “terminal” hair, hair, which is normal, permanent adult hair.

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[ninjaorange]

someones gonna get a heartattack sooner than expected.

you just combined to powerful heart drugs.

i should know ive done that.

 

[ninjaorange]

i actually tried to do that.

i think i know where the logic is coming from. minoxidil (hairgrower) + sildenafil (vasodilator) = more hair

did it for two months. did damage to my heart. tried it topically. with ceterizine too. and orally . nada.

check out my posts

 

[beholder]

i actually tried to do that.

i think i know where the logic is coming from. minoxidil (hairgrower) + sildenafil (vasodilator) = more hair

did it for two months. did damage to my heart. tried it topically. with ceterizine too. and orally . nada.

check out my posts

Actually, I am feeling a lot better after I started with minoxidil+sildenafil since my blood pressure stabilized at normal rate (I was constantly pre-hypertensive). But of course, I will go over your posts and read what happened.

EDIT: I have read and saw that you actually refer to Saw Palmetto as the cause of your heart problems. Which tells me you might just be guessing and/or your heart problems were due to some other cause, inherited, etc. Care to explain or add anything? Please don't feel offended, I DO believe minoxidil CAN cause serious side effects incl. heart damage in some people.

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Important question tho: is this the first time you started using minoxidil too ? What strength and kind (liquid or foam) were you on before ?

Yes, I was on minoxidil before, 2%. But that was 10 years ago.

This time around I started sildenafil treatment combined with minoxidil after just 1 month of 2% minoxidil alcohol-PG solution. Then I used 5% minoxidil solution but again for just about a month. Returned back to 2%. In few weeks I am going to get some more 5% minoxidil. I will cycle this low/high dose, looking for side effects. Also I am going to prepare a bit stronger V solution (sildenafil).

 

[Fbalding84]

Minoxidil is making me look like a raccoon and I had to stop. Now im shedding like crazy and I was on it for less than a week

 

[Python]

Minoxidil is making me look like a raccoon and I had to stop. Now im shedding like crazy and I was on it for less than a week

Like a raccoon? How so

 

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FBalding: Pretty much impossible to shed after 1 week of minoxidil, you need to figure out some other cause (+ androgenic alopecia). Perhaps you had stress, too much fap, etc?

For shedding quick stop try to keep your scalp dry all the time, not oily, use half of aspirin daily and use Nizoral (ketoconazole) 2-3x per week. Also try cetirizine, 20mg daily orally. And you can add topical cetirizine if you feel like it. After it gets better, you can downsize the regime.

Also, please let's keep this topic on subject.

 

[Fbalding84]

Like a raccoon? How so

Dark circles under my eyes.

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Beholder: I used your trick to make my 5% more concentrated by using a blow dryer. So I used a little bottle and sprayed the foam in there while I was warming the bottle. As the foam hit the inside of the bottle it started to become a liquid but very dense as some of eth/etc were evaporating. I would say I got 6mg of 1/3 of the foam.

As you know I have been documenting my regime and I take pictures of my hair and scalp almost everyday. There is definitely shedding after stopping min! It was just not me that noticed the dark circles under my eyes but actually more so others. My wife in particular After comparing the before and after pics I concluded it was not worth the cost associated w min. No added stress no other changed at all. It's been over a week stopping and my dark circle are beginning to disappear. I just looked as I was aging too.

I continue my regime and your suggestions just without min

 

[beholder]

gotta be careful with high concentration minoxidil. I guess that's why they normally don't make it higher than 5%. Kirkland has 15% but you won't get any higer concentration anywhere. It's also possibly related to minoxidil solubility in alcohol/PG.

My tip to you with blowdryer evaporation was for the PGF2a 0.03% solution.

 

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Continuing the log for cetirizine+minoxidil+sildenafil

It's been 2 days since I ran out of sildenafil topical solution as I needed to buy new 60% alcohol solution to make a new batch. I am making it today, thinking about making it a bit stronger than before.

Interesting thing is that my erections lately have been really really good, like to-the-point-of-pleasure good. I am also very excitable lately, p**rn really turns me on, and even after "quitting" sildenafil for 2 days the effect remained. Can easily fap 3x a day every day with the same hard wood as before. Interesting.

The only thing that really changed is that I've been recently, for the last 2-3 weeks, using a topical 10% acetylsalicylic acid and water solution with about additional 10% of MSM in it. Perhaps it increases skin absorption? Or is it the antioxidant activity of both of the above ingredients that contributes to my overall well-being? Need to study it on myself a bit more.

No shedding at all. There might be 2-5 hairs on my hands each time after I rub the solutions to my head rigorously but that's about it. Counting it up to 10-20 hairs that are out daily. I don't consider it shedding -- comparing it to my [female] fiancee I consider it quite normal.

 

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Sildenafil + Minoxidil experiment stopped temporarily

I think I am experiencing the dreaded "minoxidil face" side effecs, so 2 days ago I decided to temporarily discontinue this experiment. Just though I'd let you know guys. I am currently using only cetirizine to keep the hair I got from minoxidil, I will see if I experience any shedding from discontinuing minoxidil.

I believe the side effects I experienced stem from rubbing of the minoxidil+sildenafil from still-wet hair onto small pillow I always sleep on. The stuff was then rubbing from the pillow directly onto my face. I am a heavy sides-sleeper, additionally I turn around a lot during the night. So the stuff not only touched my face, it was actively rubbed-on.

The sides I experienced were starting to look like dark circles under my eyes. 2 day later I think it looks a little better but NEVER before I had such rings under my eyes before. I noticed them 2 weeks ago at first, thinking I need to get more sleep. I did that last week but still they were there. I put 2+2 together and immediately stopped any minoxidil use (and changed my pillow sheet).

The texture of skin under eyes is definitely changed into somewhat darker reddish-orange color (not being the healthy pink color). There was also a small edema 1-2 days ago, I think, that somewhat disapeared. Not sure yet, will see in the next few days. But circles still stay there, whether it's morning or evening, it doesn't matter. They look more like quarter-circles, than full half-circles. I have increased my collagen intake and keep the antioxidants intake to keep the skin collagen building going on. I have also gently exfoliated the area using ascorbic acid.

I expect the skin to return to normal within a month or two in the best case (a year or two in the worst case). As soon as I see signs of radical improvement, I will start with minoxidil+sildenafil again, this time daily application of 2% minoxidil and washing my hair at night. In any case, I will keep watching it.

Needless to write, this has most probably NOTHING to do with sildenafil. Please keep that in mind as you re-read this post. I just wasn't careful with minoxidil, as it happens sometimes.

 

[Fbalding84]

I feel you bro. The raccoon face side effect made me stop minoxidil too

 

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How long did it take you to get back to "normal"?
Any specific wrinkles in the affected area?

 

[Fbalding84]

I used it less than two weeks but I used a more concentrated solution I must have also overdosed on it. I Share the same sleeping habit with you so that didn't help much either. The bags are almost gone within 2 weeks now but wrinkles have reduced but still present. The wrinkels were most noticable around my eyes, crows feet and under my eyes.less in my forehead.

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But eventhough I didn't use it for a long period. I am shedding like crazyb!!!!! Small hairs,long hairs, thick hairs and miniturzared hairs.

 

[beholder]

Perhaps you need to block DHT and PGD2 some more. Try a cetirizine water solution and vitamin C (ascorbic acid) + MSM water+alcohol solution. Seems working for me, no hairloss yet, although hair feels 'hard' and dirty all the time.

I also recently quit acetylsalicylic acid (aspirin) for a while but in the worst case (a lot of shedding) you can try half a tablet daily for 2 weeks just to stop immediate shedding. It should decrease PGD2 markedly.

http://www.researchgate.net/profile...nt_of_Alopecia/links/541138e50cf2d8daaad3e5b2
http://www.biomedcentral.com/1471-5945/4/13
http://www.ncbi.nlm.nih.gov/pubmed/19416266