I've translated it with translator Deepl. Some parts may not be correct.
I wondered if this was the case. If the hematopoietic stem cells, which were being developed at Niigata University, could be turned into a drug for treating autologous blood disorders, it would certainly be a cure for autologous blood disorders. However, the company's top management decided not to develop the drug, fearing that it might be contagious if it used human cells. Descent. is the row that would later lead to making stem cell-based therapy, or regenerative medicine, a life's work. After finishing his doctoral studies in 1973, he joined Japan Tobacco Inc. and was assigned to the Life Science Institute in Yokohama, Japan. Then, he was hired a year earlier, and he immediately hit it off with Yasuhiro Fudwara (currently a professor at Osaka University), who was three years younger than him. He immediately got along with Yasuhiro Fudwara (currently a professor at Osaka University), who had joined the company a year earlier and was three years younger than him. According to Toshihara, Tsuji was friendly, without being "too old for him". They had one thing in common, too: they were both sons of local shopkeepers and had a passion for fishing. Both were sons of local shopkeepers and had an unparalleled love of fishing. After a year of lively discussions about research and research, Kajiwara was transferred to Yokohama City University and Tsuji was transferred to JT Pharmaceuticals, Inc. He moved to the Discovery Research Institute in Yokohama, Japan, but the Bunryu continued. Tsuji's research focuses on the proliferation of hematopoietic stem cells in the umbilical cord blood of newborn babies in vitro1. At JT, he wrote a paper on hematopoietic stem cells, which became a major beer-boynt. At the University of Science, he taught a course on non-specialized subjects such as pharmacology, chemistry and physiology before he was an undergraduate. The university was blessed with a high level of funding among private schools and its students were serious. However, I was assigned to a laboratory with 10 students per year. I was assigned to a laboratory, which had an annual stipend of ten students, and I had to supervise more than a dozen students, including those in the graduate school. When I was a student at Kyushu University, I felt a sense of tension and a sense of alienation in the Spartan laboratory HeC, but I was the leader of The pressure from the height of purpose and the difficulty of managing a lab with many members when you become a I was confronted with the fact that I was in the same position as Dr. Nakamura. He said, "Having been in the same position, I can now fully understand how Dr. Nakamura felt about his feelings of unity and loneliness. I'm sure that I'll be able to help him more if I'm on my own now, and I'm sure that the relationship with Kajiwara, a colleague of mine from JT, will be very important. This was the beginning of a unique encounter with Otsuka Chemical. This was the point of contact with Otsuka Chemical, which later became a researcher in the regeneration of organs such as teeth and hair. Kajiwara, who specialized in glycoscience, was engaged in research together with Otsuka Chemical. Tsuji was put in charge of the biological evaluation of tambac proteins synthesized by Taxahara and linked with glycolysis, and he was assigned to work with Otsuka Chemical in the field of science and technology. Otsuka Chemical Co., Ltd. entrusted me with its first endowed lecture series at the University of Tokyo, and my original specialty, regenerative medicine, is the study of three-dimensional organs. The aim is to regenerate. The large and complex structures of the liver and other organs are created in accordance with the biological principle, and are covered all over the body surface. If "teeth and hairs are not directly linked to life and death," it would be easier to build an experimental model, so Tsuji quits JT and moves to the University of Science. After immersing himself in research and education, Tsuji decides to leave JT after seven years of service. He had the confidence to think about his research theme, implement it, and write a paper on it. He wanted to take the initiative in researching a new field that would lead to practical applications, and he asked the university to fight for him. At that time, he was appointed as a faculty member of regenerative medicine at the Tokyo University of Science's School of Engineering and Technology and became an assistant professor in 2001. . In the whole industry, patents are more important than papers.
I got it. Tsuji is a good presenter. Since his time in the corporate world, he has how to persuade his superiors by using management's words to persuade them. We make sure that all students and staff members, including those who have been working at the University, are fully aware of the importance of greetings, keeping their promises, and beilearnedng organized. This is because he believes in the importance of the researcher as a human being. Mayumi Murofushi, an assistant at Riken, said that a student of hers at Ritsumeikan University T There are a lot of things that are line packed and I have a lot of sympathy for [Tsuji's] beliefs," Aogan said. The company is not only engaged in the field of regenerative medicine, but also in the field of health care. In 2006, he led the world in the development of artificial skin for the evaluation of the safety and functionality of cosmetics and quasi-drugs. It was released. In the midst of the trend of banning animal testing, this product is attracting a lot of attention as the next generation of artificial skin. Tsuji is also aiming to commercialize hair diagnosis. RIKEN has been working on it for some time now, saying, "I understand the words of people in the light industry, and I have a good idea of the seeds that companies are looking for. I'm sure I'll be able to play a role in bridging the gap with companies. In June, Tsuji was appointed to a position at RIKEN, but while he was being held accountable for the research fraud surrounding STAP cells, Sasai's father, a former professor of chemistry at the University of California, Berkeley, was also being held accountable. The loss of his spiritual pillar and supreme mentor, a comrade who took his own life in August of that year, made Tsuji For a short time he was at a loss for words, but Yoi, who was busy with industry and academia, entrusted him with the mission of "fusion cooperation" which was completed in five years. The idea is to attract companies to the Innovation Promotion Mechanism. The external funds obtained from the joint research with Tsuji alone will be used to pay for all the joint research that RIKEN receives from companies. It reached 10%. Like the pre-war science and research centers, it is an independent, self-financing, two-year organization. We aim to pursue our research and collaborate with private companies for the practical application of hair follicle regenerative medicine, and to apply the seeds of our research and Organ Corporation, which was recognized as a "RIKEN Venture", formed a partnership with Kyocera. Kita, who sympathized with Inamori's philosophy, directly contacted the founder of the company, Kazuo Inamori, and signed a contract with him on August 8, 2002. It was cultivated and made more than 5,000 hair follicle taphone-the equivalent of 10,000 hairs. In an experiment in which these were transplanted into mice, the hair regenerated and was replaced for life. It is expected to be a treatment for not only male pattern baldness, but also for intractable hair growth disorders such as congenital Whairui syndrome. On the other hand, in the area of tooth regeneration, Harumei of Tokyo Medical and Dental University and Masao Oshima, an associate professor at the University of Tokushima and a pupil of Tsuji's, have been working with The next generation of "hybrid implants" is under development. The company has been working on the development of a new type of implant to replace missing teeth, which is widely used to attach an artificial tooth to a full alveolar bone. This is not a good treatment. In this case, the artificial root membrane is connected to the alveolar bone through the artificial south root membrane to provide the same physiological function as a natural tooth. Reproduction. The artificial tooth has the advantage of not becoming an orchid and regenerating organs while enhancing their function. The company has already achieved success in experiments on dogs, which have a strong ability to blow together, and is aiming for early commercialization. Tsuji, who is particular about useful research, has been pursuing innovative basic research innovations that will help to make Japan's health. This is the mission of his own. The realization of this mission is my mission. The company is developing a traditional way of doing business. First institutions such as Organ, Yahoo, and Aderans establish a consortium, and joint research is a star". And then the clinical research of the real life hair - a clinical study of about 100 hair follicles taken from Sekikata's scalp.
However, he had neither the knowledge nor the research experience on the development of teeth. He was introduced to Kasugai Shohei, a professor of dental implantology, by Kazuhiro Eto, the vice president of Tokyo Medical University. It was made. It's a cloud-grabbing story, and I don't think it's going to be possible," said Kasugai, who was consulted by Tsuji for nine years When these tooth seeds are transplanted into the adultus, the teeth with blood vessels and nerves regenerated for 8 years, the adult mouse's teeth If you plant it in the area where the tooth came out, you'll have a complete set of teeth that will grow back in just over a month, and you'll have a perfect fit and feel the pain. Successful regeneration. Kasugai was taken aback by Ichijitsuji's research sense, and in two years, he succeeded in the regeneration of hair from hair seeds. Because hair grows in a fixed cycle, only two types of stem cells necessary for official regeneration are available in adult organisms. In teeth, a seed for a tooth can only be made from the toothpaste of milkshakes or shui-ku'er. In order to regenerate a tooth in a toothless adult, the stem cells that can be used for tooth regeneration must be deepened, which is one of the barriers to practical use. In his early years, Tsuji founded Organ Technologies, a venture company with the support of Otsuka Chemical. In his early years, Tsuji founded a venture company, Organ Technologies, with the support of Otsuka Chemical. In order to put Tsuji's technology to practical use, a number of patents, including one for the organ germ method, must be consolidated The University of Science and others have filed a pre-patent petition for a patent, and the company needed a box to stock it. The University of Science and others received a pre-application proposal for the patent, and the company needed a box (company) to stock it "passionately and sharply dropped. The "V" is an endowed lecture given by the Organ Corporation in its year of residence, bringing new life to an old company like Otsuka Chemical. In 1996, he became a full-time research professor at the University of Science. In the following year, the University of Science constructed the Organics Regeneration Engineering Project, and it became a major research center of the Organ Corporation. In 2000, the Organ Regeneration Engineering Project was established at the University of Science, and it became a major research center of the Organ Corporation. However, a miscalculation occurred. The support from Otsuka Chemical differed from the original plan and was cut off after 4 years. The business was reviewed. However, Tobe continued to invest in the company privately even after it was separated from Otsuka Chemical, and he continues to meet with Tsuji several times a year. For Tsuji, who was a close friend of Otsuka Chemical's business reports, it was a form of support from Otsuka Chemical. However, a new opportunity opened up for him in a different way. Yoshiki Noui, a leader in regenerative medicine and a former researcher at Riken, invited him to join Kyoto University's Department of Regenerative Medicine for two years. The same age as Noui, who sat with him at a lecture at the institute, was a supervisory stem cell (E) student. Tsuji had been fascinated by RIKEN since his high school days. The history of Riken dates back to before World War II, and Sasai, who had a high standard of research and an air of respectability, told him that Riken was a good place to work. I was invited to be the Group Director, but I turned down the offer twice, thinking I was not suited to the position. In the end, I decided to apply for the position because I wanted senior researchers to be responsible for applications and young researchers to focus on basic research. He shared Sasai's desire for a "tooth", so Tsuji learned about the principle of the development of the South and exchanged ideas with him. He is convinced of the regeneration from the "Tanee" (the original organ of music). He made the base of the organ, the seed, and grew it and regenerated it into a 9-toto organ regeneration and play AK Me. When a clear mammal with a good research sense is in the embryonic stage of development, the seeds of organs needed for a specific location are stem It is made from cells and grows into an organism. Tsuji took a rakugo story from a mouse nodule, which was determined to become a tooth in the future, and created an epithelial stem The cells were paralleled into two types of stem cells and cryptogenic stem cells. These two types of stem cells were combined into a two-layered structure in a single high-degree trial, and the "Southern Seed" type S method was named "Instrumental Palace Method". This led to the success of the revitalization of the government, which was largely due to the wise decision of Otsuka Pharmaceutical Co. Initially, Organ was established as a wholly owned subsidiary of Otsuka Chemical, and Otsuka Chemical was the only company to provide research and development funds to the government. Sadanobu Tobe, then president of the company (now. Otsuka Tobe was overwhelmed by Tsuji's heatsuke in his first game against