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Recently i asked Breezula for participation in clinical study in Germany... thanks for your advice
Update From The God Himself - Dr. Takashi Tsuji
- Thread starter kingjohn
- Start date
Recently i asked Breezula for participation in clinical study in Germany... thanks for your advice
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Someone can help me? i know that in this moment there aren’t official news and info, but i want to know some info about..
1) there are some limitations about how many hair follicles can be injected for singol session?
2) i’m 3 Norwood scale, i got thin hair on the front. if i do the Tsuji hair transplant i will find on my head some thin hair (old hair) and some thick hair (new hair)..that’s the truth?
3) it’s possible to insert follicle in the temples zone? i mean on the sides
4) if i do the Tsuji hair transplant, there are no problems for my new hair, but for my old hair there are still the same problems...so over time could be necessary a new transplant? (one session is expensive but two is impossible)
1) there are some limitations about how many hair follicles can be injected for singol session?
2) i’m 3 Norwood scale, i got thin hair on the front. if i do the Tsuji hair transplant i will find on my head some thin hair (old hair) and some thick hair (new hair)..that’s the truth?
3) it’s possible to insert follicle in the temples zone? i mean on the sides
4) if i do the Tsuji hair transplant, there are no problems for my new hair, but for my old hair there are still the same problems...so over time could be necessary a new transplant? (one session is expensive but two is impossible)
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It is early to discuss even commercial release date. If you want real answers and not like reflections on the topic you really need to wait some time.
H
Senior Member
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Boy am I glad my hairloss is aggressive for this very reason hahaha (sobs uncontrollably)
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If this fails we are done for maybe decades, so hope or hm.. hope until they officially say we screwed it
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You do realize that this guy didn't start his work yesterday? It's almost a decade and until now he never lied, just like f*****g every other company did..maybe a small delay, but he should be the first to deliver
Remember follicum (or samsumed, cant remember which company) said they would make an announcement regarding phase 2 completion in “late october” and literally waited until oct. 31st to make the announcement.
It’s only March 9th. I’m sure we’ll hear something in the next few weeks.
It’s only March 9th. I’m sure we’ll hear something in the next few weeks.
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I don t know your math skills... but i know tsujis math skills is asian level. So i would trust their calculation more
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There You have got your Update:
Takashi Tsuji
6 March 2019
https://royalsocietypublishing.org/doi/10.1098/rsob.190010
Hair follicle development
Mice have four different types of hair on their backs, classified as guard, awl, auchene and zigzag hairs. Hair follicle development in the mouse back skin begins with the fate determination of mesenchymal cells at approximately ED 10.5, resulting in the formation of a dermal condensate. Reciprocal interactions between the dermal condensate and overlying epidermis lead to the induction of the hair placode (figure 3a). Once the hair placode is established, hair follicle development occurs in three waves, starting with the development of the guard hair at ED 14.5, followed by awl and auchene hair at ED 17 and zigzag hair at birth [45,46]. The lower end of the hair peg epithelium that wraps around a condensed dermal cell forms the germ of the hair matrix. The condensed dermal cell forms a dermal papilla, which is considered a niche for hair follicle mesenchymal stem cells, and induces the differentiation of the hair matrix and forms the inner root sheath of the hair follicle and the hair shaft. The bulge region also forms an epithelium stem cell niche and simultaneously connect with nerve fibres and the arrector pili muscle
Takashi Tsuji
6 March 2019
https://royalsocietypublishing.org/doi/10.1098/rsob.190010
Hair follicle development
Mice have four different types of hair on their backs, classified as guard, awl, auchene and zigzag hairs. Hair follicle development in the mouse back skin begins with the fate determination of mesenchymal cells at approximately ED 10.5, resulting in the formation of a dermal condensate. Reciprocal interactions between the dermal condensate and overlying epidermis lead to the induction of the hair placode (figure 3a). Once the hair placode is established, hair follicle development occurs in three waves, starting with the development of the guard hair at ED 14.5, followed by awl and auchene hair at ED 17 and zigzag hair at birth [45,46]. The lower end of the hair peg epithelium that wraps around a condensed dermal cell forms the germ of the hair matrix. The condensed dermal cell forms a dermal papilla, which is considered a niche for hair follicle mesenchymal stem cells, and induces the differentiation of the hair matrix and forms the inner root sheath of the hair follicle and the hair shaft. The bulge region also forms an epithelium stem cell niche and simultaneously connect with nerve fibres and the arrector pili muscle
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"Because hair follicle stem cells are the only adult stem cells possessing organ-inductive potential that can be transplanted autogenously, the first human clinical trial of organ regenerative therapy will undoubtedly investigate hair follicle regeneration. The regeneration of hair follicles using our organ germ method is now being investigated in a pre-clinical study to cure patients suffering from androgenic alopecia, with an aim of conducting clinical trials in 2020. This hair follicle regenerative therapy will be a milestone in organ regenerative therapies and will lead to the development of material and responsive infrastructure to realize organ regenerative medicine. Applying knowledge of hair follicle regeneration and expertise obtained from clinical trials to other organ germs or organoids will enable the regeneration of other organs from pluripotent and tissue stem cells in combination with organoid technologies in the next few decades."
Positive- the mouse studies showed fully functioning, properly cycling hair follicles that connected to the arector pili muscles. Also, they seem very very confident they will reach human trials.
Negative- March 2019 was optimistic. Clinical trials planned for 2020.
Positive- the mouse studies showed fully functioning, properly cycling hair follicles that connected to the arector pili muscles. Also, they seem very very confident they will reach human trials.
Negative- March 2019 was optimistic. Clinical trials planned for 2020.
Great find sir, thank you.
I think it was pretty obvious that 2020 was an overly optimistic relase timeline. That being said, this is great news. There is no other organization that is nearly this confident about their research.
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Isn't a "clinical trials" in japan close to a "market release" while still doing the research part if it is safe within a year?
And yeah..god damn it Tsuji is the Messiah!
New tooth is also quite interesting..
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Does anyone know “ball park figure” how much this treatment will be ?? Or is it a continued treatment ?
From my understanding, certain treatments (cell based therapy?) only need one trial before going to market. There must be conditions, I'm not sure though.