Update On Prostaglandin Protocol. Officially An Alternative To Finasteride And Minoxidil.

[westonci]

I resubmit my question:
@westonci What do you think about the topical use of setipiprant? I talk about an high concentration, using salted setipiprant, like 10 or 15 %. Just for manteinance with less costs. Just your opinion, thank you.

Its hard to say, keep in mind the CRTH2 has to be blocked 24/7. So you might need to apply every 12 hrs to block it. Doesnt seem feasable if you have an active social life.

Then again some people here have claimed they had really nice results with 10-15% kane seti. So I could be absolutely wrong.

Also please dont neglect the PGE2+microneedling part. Thats where all the regrowth is at. Seti is just for maintenance/stopping further loss.

 

[aemxle]

I know the pge2 question. But... is impossible to buy now and to use without have testing it...

Use of topical seti is not a problem for me. I have a short hair cut and already apply minoxidil every 12 hours... Just add seti in minoxidil bottle... and use the pg in the minoxidil to vehicle it.

 

[MomoGee]

People need to stop going crazy about the price. This is black market stuff lads!!

If Seti actually gets released to the market it will likely be at a much lower cost compared to Kane's prices.

 

[westonci]

I know the pge2 question. But... is impossible to buy now and to use without have testing it...

Use of topical seti is not a problem for me. I have a short hair cut and already apply minoxidil every 12 hours... Just add seti in minoxidil bottle... and use the pg in the minoxidil to vehicle it.

Hey that might be a good idea. Try Seti and minoxidil+Microneedling

 

[kiwi666]

Before (April 2016)

• https://i.imgur.com/sJVkg0U.jpg
• https://i.imgur.com/rZl04Hm.jpg
• https://i.imgur.com/pQT0moI.jpg
• https://i.imgur.com/YIJse3O.jpg
• https://i.imgur.com/n1eOXB9.jpg
• https://i.imgur.com/s0DmPj8.jpg
• https://i.imgur.com/d3fRPCf.jpg
• https://i.imgur.com/uKafrh0.jpg
• https://i.imgur.com/CAozCmY.jpg
• https://i.imgur.com/cE9YBqm.jpg
• https://i.imgur.com/JNiHSXW.jpg

After (May 2018)

• https://i.imgur.com/puyxrqp.jpg
• https://i.imgur.com/Mx5Agv2.jpg
• https://i.imgur.com/1v8WkwA.jpg

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Pros

• No sexual or anti-androgenic sides like finasteride i.e erection/libido issues, thinning the beard (allegedly), body comp changes
• no skin sides like minoxidil i.e bloating/water retention, dark circles, wrinkles (allegedly)
• You can get it right now through private sources

Cons

• Expensive as f***. Seti is $11/day @ 2g/day and PGE2 is about 70 cents/day @ 1mg/day.

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My Current Regimen

• 1g Setipiprant taken orally every 12hrs
• 1mg Prostaglandin E2 in 3ml of distilled water applied topically to scalp after very lightly microneedling session (goal is not wounding or to draw blood and should not be painful!). I usually do this every other day.

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Thoughts

This has been a looong ride with a lot of tinkering and trial and error. I can say that all of the growth is from pge2+microneedling. Seti is only for maintenance and a prerequisite for pge2 to work. For pge2 to work you must also microneedle before applying it.

I made a huge mistake in assuming that seti would be enough and all that was needed to get regrowth. I can not stress how important both are (Seti+pge2) and it makes sense since Allergan the company thats doing trials for seti is also doing trials for bimatoprost a PGF2α agonist.

Im making really good gains still. The areas where I had hair but were thinning (my vertex area) are extremely thick now. im 100% satisfied for those areas.

As for my temples and crown where i had severe hairloss its filling in very nicely.

EDIT: You dont have to wait 2 year for these results.

Almost all of the regrowth have been in the last 3 months because of the PGE2+microneedling I added.

Seti alone will only give you maintenance and why I got a lot of flack for posting updates with minimum results over the last 2 years since people were expecting solid regrowth (I did Seti alone for a while and then I did PGE2 in ethanol topically but in hindsight it turns out the PGE2 in ethanol didnt do much now that I recently started with PGE2+microneedling)

Like i said it was all trial and error and it looks like Im finally on to something with the PGE2+microneedling

Thanks for the update. Awesome results

I just a thought. At $11 a day you’re looking at around $4000 per year.

What if you did this treatment every second day? Then it’s down to $2000...

Heck what if you only ‘needed’ to do it once a week (long shot).

What are your thoughts on those kinds of variable factors?

 

[westonci]

Thanks for the update. Awesome results

I just a thought. At $11 a day you’re looking at around $4000 per year.

What if you did this treatment every second day? Then it’s down to $2000...

Heck what if you only ‘needed’ to do it once a week (long shot).

What are your thoughts on those kinds of variable factors?

Unfortunately Setipiprant has a 12 hour half-life

Seti is actually dirt cheap to make, but we need to put immense pressure on these chinese labs to lower the prices since they are price gouging us because they can.

 

[whatevr]

I was not sarcastic ... I'm really relieved. We have our cure. A lot of guys after seeing this post are going to jump on Seti. You will see.

Mhm. Of course.

 

[aemxle]

@westonci why you think that microneedling can help with topical setipiprant? It's not for pge2?

And, last question: what can i use to microneedling?

Thank you, and scuse me for the question.

 

[ChildOfNature]

*Jumps off Brotzu hype train*
*jumps on to Seti hype train*

 

[Dat5Years]

They are crazy results for 3 months man! I wish I wasn't poor so I could afford to jump on the regime haha. Hopefully price will go down

 

[westonci]

@westonci why you think that microneedling can help with topical setipiprant? It's not for pge2?

And, last question: what can i use to microneedling?

Thank you, and scuse me for the question.

No that would be a bad idea. Seti requires ethanol/dmdo for a vehicle. You dont want ethanol/dmso all over your scalp after microneedling.

I use water as my PGE2 vehicle so its no problem.

 

[Appletree101]

Can you PM me regarding a source for seti and PGE2?

 

[westonci]

Can you PM me regarding a source for seti and PGE2?

Im currently getting my Seti from Lewis who used to work at Zhe Chem. You can contact him at LewisWei@hotmail.com

As for PGE2 i have 300mg left from the private forum that should last me another 8 months.

Once I run out though Im going to be forced to find a supplier on Ali baba and have it tested and get back to you guys.

 

[kiwi666]

*Jumps off Brotzu hype train*
*jumps on to Seti hype train*

There was never a brotzu train. Just the millennium hype train.

 

[itsjustsimon]

Could pge2 be used with minoxidil?

 

[aemxle]

No that would be a bad idea. Seti requires ethanol/dmdo for a vehicle. You dont want ethanol/dmso all over your scalp after microneedling.

I use water as my PGE2 vehicle so its no problem.

Correct me if i'm wrong, but, minoxidil has ethanol and propilen glicol as vehicle, so it's a good idea to mix setipiprant directly, or no?

 

[Murkey Thumb]

Wow! Great results Westonci you have basically regrown your crown from slick bald to something acceptable. If i could afford it i would be all over it like a rash!

 

[Badbald]

Westonci, amazing results congrats and thank you for sharing your results and protocol. It seems like the PGE2 is going to be the hard part to source and from your findings is an important part. Could minoxidil work in anyway similar to your source of PGE2 and be a legitimate alternative or is its pathway completely different?

 

[kiwi666]

Unfortunately Setipiprant has a 12 hour half-life

Seti is actually dirt cheap to make, but we need to put immense pressure on these chinese labs to lower the prices since they are price gouging us because they can.

Does that matter. What would happen if you have 12 hours without it? Would that down time ruin everything?

 

[westonci]

Does that matter. What would happen if you have 12 hours without it? Would that down time ruin everything?

Allergan is doing twice a day 2g.

The 12 hr half life means your body flushes out half the seti in 12 hrs.