Very Impressive Dermarolling And Minxodil Results - From Tressless

bucksins6x

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Does anyone know if it matters what one I buy? One is cheaper
 

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devz

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Is minoxidil 2% without derma can ruin your hair? I got diffuse pattern and 5 months ago I started with minoxidil 2% without needling, the left receeding hairline is becoming thinner instead of improving
 

Okocha121

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Hi

I would like to know what is the best dermaroller to buy? A Dermapen is really better than a simple dermaroller?
There are a lot of examples which people got amazing results but do we have some better ideas about how it works now?

Thanks
 

NorwoodGuardian

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Many who had good results used cheap pens or even simple derma roller. Don't think it will make a lot of difference

That’s why I doubt Follica’s patent makes big difference. Those who got good results before the patent was released wounded randomly, many wounded to bleed and one of them even butchered his scalp. So I begin to think that deep wounding is better than mild redness wound.
 

NorwoodGuardian

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For those interested in understanding the science, these studies may be helpful in giving a better understanding of what happens during micro needling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921236/ & https://www.ncbi.nlm.nih.gov/pubmed/29199946 Interpret however you like but here are some of the highlights.....lending credibility to shallow depth at high concentration (quorum sensing):

  • Skin cuts to a depth of 0.5–0.6 mm close by electrical cell stimulation without any trace of scar tissue. Deeper skin cuts close by “skin repair” that ultimately results in scar formation.
  • The theoretical method of action of microneedling may include trans-epithelial potentials (TEP's) suggesting the response is based on electrical signaling and the mobilization of local stem cell pools to promote tissue regeneration and repair
  • Only cells in the vicinity of the injury (about 2–3 mm) are activated. Once the TEP is restored the activated cells resume their resting potential. To elicit a desired response from microneedling about two hundred needle pricks are created per cm2 of skin.
https://www.hairlosstalk.com/interact/attachments/skincellproliferationmnd-pdf.133534/

Here's the Follica presentation with some more info about skin disruption and the creation of new hair follicles: https://www.hairlosstalk.com/interact/attachments/follica-clinical-summary_compressed-pdf.132602/

200 needle pricks? Not 1600 according to patent?
 

coolio

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If I had to guess, I'd say they stopped at 1600 holes because it wasn't practical to keep trying to add more.

Try drawing 1600 little dots on a square centimeter of paper. You realize that's A TON of holes in a tiny space. It's effectively carpet-bombing the area. And pushing needles into skin is not as precise as making dots on paper with an inkpen. The skin is softer. After a certain point the needles will just be landing back into previous holes.

That tipping point will be different for different individuals but you get the idea. To do clinical trials they had to decide on a specific number and stick with it.

For our experimenting purposes, I really doubt it would cause any harm to overshoot past 1600. Dermabrasion does more damage than any amount of poking holes, and even that is not harmful with adequate recovery time afterwards. Just use common sense.
 
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Jesse14

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Yes. The quorum sensing study shows that if you pluck every hair then nothing grows back. Also, if you create the effect of one large wound you will get scarring with only hair in the center of the wound. That is unless you use an shh agonist. If you look at the Follica studies they show demabrasion doesn't work nearly as well as microneedling.

That said, you're more likely to underwound than to overwound.
Can you even get scarring from needling at depths 2.0 mm and under? I think I read that in another thread, but I may be wrong. I needle pretty thoroughly at 1.75mm weekly, and hope I haven't screwed myself.
 
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