What if finasteride is not equally distributed in 5mg proscar?

[bluejs]

I am having concern with taking proscar (I would really like to get propecia if I were rich)

in that 5mg proscar, for example, what if it has like 4mg finasteride on one cornor and 1mg in others?

in that case if u cut in 4 peice, u have high chance that u are ganna get 4mg finasteride one day, and 1mg for three days,,

is there any evidence that the finasteride is almost equally distributed in 5mg proscar?

 

[Aker]

Hi bluejs,

From what I've read on these forums, a small variance in intake from day to day shouldn't hurt your results. I would use your judgement when splitting the pill to keep it in equal quarters. If you are getting 4mg one day and 1mg the next, you've split the pill incorrectly. If you get 0.8mg one day and 1.2mg the next day - continuing throughout the week, it shouldn't matter.

I'm no expert, but this is just from what I've read on the forums so far.

 

[MPBWarrior]

bluejs,

don't worry about it!!! its muuuuuuch cheaper!!! and it takes ages for DHT levels to rise again, so dont worry if u dont get exactly 1.25mg of finasteride every day!!! but Aker is right.... if you're getting 4mg of finasteride in a day, you're certainly splitting the pill wrong!!!

 

[bluejs]

but what I mean is that

even if I cut exactly 1/4 volume, it still could be 4mg on one side if

the finasteride is not equally distributed in that one proscar 5mg.

any one sure that it is almost equally distributed?

 

[Aker]

I see what you mean now. Again, I'm no expert, but the finasteride within the pills should be evenly distributed across the entire pill. Especially with the regulations that U.S. pharmaceutical companies have to face to be able to put drugs on the market.

Many people split other prescription drugs every day, so I can't see how finasteride would be any different.

 

[TA45]

My derm told me to stay away from Proscar for that very reason. He stated that the Finasteride is not evenly distributed.

 

[beaner]

It would have to be evenly distributed just based on how drugs are made. They are produced in factories in mass quantities. From my understanding its just a vat of the drug mixture compressed into pill size. The finasteride would have to be evenly distributed within the mixture otherwise there would be no way to be sure there is 5mg in each pill without testing each one, which would be impossible. Drug companies just say this, I'm sure, to deter exactly what us baldies use Proscar for. Think about it.

 

[bubka]

that would be an amazing act of chemistry and formulation if they could make a pill that are all 5mg yet have the active ingredient concentrations different throughout the pill...

hmmm, come on guys, lets use some common sense here…

 

[MPBWarrior]

great words bubka!!!!

 

[Aker]

I'm not sure it would be so difficult to create a pill with an uneven distribution of the active ingredient. I would say it all depends on what the ingredients are, and if they're a solid or liquid to begin with. I can easily imagine someone trying to make a pill in their basement, and not mixing the ingredients up all the way prior to making the pill, especially if it's just a big bucket of ingredients to begin with.

 

[Bryan]

that would be an amazing act of chemistry and formulation if they could make a pill that are all 5mg yet have the active ingredient concentrations different throughout the pill...

hmmm, come on guys, lets use some common sense here…

Totally agree. I guess some people believe that each pill is constructed meticulously as it rolls down an assembly line, much like a Ford pickup truck: first, some tablet filler is injected into a mould; then, a tiny little injector needle squirts a microscopic dollop of the active drug into one corner of the tablet; then, little mechanical robot fingers turn the pill around 90 degrees, and the needle injects another tiny dollop of drug into another corner of the pill, then this process is repeated another couple of times. Then the tablet is flipped upside down, and the previous process is repeated on the underside corners. This is done for each and every one of HUNDREDS OF THOUSANDS of Proscar tablets, just for the specific purpose of making life difficult for patients who might be thinking of splitting their tablets into smaller doses!

Bryan

 

[bubka]

yeah, i heard that Merck originally makes the pills 7mg, but has workers radomly drill out 2 holes in each pill of 1mg, then fill it with a filler so it is not evenly distributed now and yet still 5mg total :lol:

 

[Aker]

Ford? Meticulous? That was the worst analogy I've ever seen. :lol:

Either way, I bet I could easily make a pill that has an uneven distribution of the active ingredient. I don't know why you guys act like this is impossible.

As far as Merck goes, yeah, it's not going to happen, but if you think all pills are perfect, why not just order them from anywhere?

 

[Guest]

but if you think all pills are perfect, why not just order them from anywhere?

And Aker built a pretty man but he was made of straw.

The reason why people don't order pills from some sites is because they are concerned that the pills are fake, not that they don't contain finasteride.

 

[bubka]

Ford? Meticulous? That was the worst analogy I've ever seen. :lol:

Either way, I bet I could easily make a pill that has an uneven distribution of the active ingredient. I don't know why you guys act like this is impossible.

As far as Merck goes, yeah, it's not going to happen, but if you think all pills are perfect, why not just order them from anywhere?

there is a big difference between being genuine merck, then bying brand x from interent xxx . com or whatever

the pills are consistant, unless my theory is correct :lol:

 

[Bryan]

Ford? Meticulous? That was the worst analogy I've ever seen. :lol:

Hahah! I guess that was indeed a bad choice of words!

Either way, I bet I could easily make a pill that has an uneven distribution of the active ingredient.

Ok, I'll bite: how would you do that on a mass-production basis?

Bryan

 

[Bryan]

The reason why people don't order pills from some sites is because they are concerned that the pills are fake, not that they don't contain finasteride.

Is there a subtle distinction between a Propecia pill that is fake, and one that doesn't contain finasteride?

Bryan

 

[Guest]

The reason why people don't order pills from some sites is because they are concerned that the pills are fake, not that they don't contain finasteride.

Is there a subtle distinction between a Propecia pill that is fake, and one that doesn't contain finasteride?

Bryan

Sorry lol. I was tired when I wrote that

What I meant to say was this:

"The reason why people don't order pills from some sites is because they are concerned that the pills are fake, not because they think the pills don't contain an even distribution of finasteride in the tablets. They are concerned about there even being finasteride in the tablet rather than some useless powder.

 

[I_Hate_DHT]

My derm told me to stay away from Proscar for that very reason. He stated that the Finasteride is not evenly distributed.

Exactly. That is the first problem with Proscar. That's why I take Propecia. :wink:

The second problem, and maybe not as important as the first one, is that when you cut in pill into 4ths, you take the 4th part on the 4th day. So, the 4th part stays out of the packet for 4 days, which is not a good idea according to merck. I think max is 12-24 hours.

 

[Guest]

i hope you are being sarcastic dht