What if Latisse (bimataprost) Was Affordable?

[RoySmith]

Right now, it costs $150 a bottle for a 0.03% solution and you may have to use multiple bottles a month but IT WORKS! I found out that it works as well as minoxidil (give or take) but no side effects. If it was cheaper, many of use would have this in our regiment but it's a car payment a month minimum to use it.

I mention this because I spoke to a chemist that has prostaglandin technology that could make this way cheaper and actually affordable. He also said he experimented with a variation of bimataprost that he believes is more effective (that may take years though due to FDA). Would you guys purchase and use bimataprost if it was more affordable? Do you foresee any issues?

 

[JaneyElizabeth]

Right now, it costs $150 a bottle for a 0.03% solution and you may have to use multiple bottles a month but IT WORKS! I found out that it works as well as minoxidil (give or take) but no side effects. If it was cheaper, many of use would have this in our regiment but it's a car payment a month minimum to use it.

I mention this because I spoke to a chemist that has prostaglandin technology that could make this way cheaper and actually affordable. He also said he experimented with a variation of bimataprost that he believes is more effective (that may take years though due to FDA). Would you guys purchase and use bimataprost if it was more affordable? Do you foresee any issues?

Maybe if it were cheaper. I buy from Thailand and tiny little bottles for $40 or something. Oral minoxidil might work better for lashes than latisse anyway so since I am taking oral min, I will just finish up the latisse on hand. Now, tretinoin, that's worth the bucks.

 

[JaneyElizabeth]

Just for you, Pls:

 

[pegasus2]

Lots of people use bim or something similar. Like you said it has about the same efficacy as minoxidil, but it has the same collagen side effects.

The good and bad side is that it works for everyone unlike topical minoxidil, but it probably doesn't work as well as minoxidil for the people who actually respond well to minoxidil.

 

[RoySmith]

Lots of people use bim or something similar. Like you said it's about has about the same efficacy as minoxidil, but it has the same collagen side effects.

The good and bad side is that it works for everyone unlike topical minoxidil, but it probably doesn't work as well as minoxidil for the people who actually respond well to minoxidil.

Yeah but the collagen side effects are the worse that's been reported. You're not gonna get a higher heart rate, chest pain, lower blood pressure, or dizziness with bimataprost. If it could be brought down to the price of minoxidil, why should we even use minoxidil anymore?

 

[JaneyElizabeth]

Yeah but the collagen side effects are the worse that's been reported. You're not gonna get a higher heart rate, chest pain, lower blood pressure, or dizziness with bimataprost. If it could be brought down to the price of minoxidil, why should we even use minoxidil anymore?

That's what retin -a and microneedling is for. I have it all structured out.

 

[pegasus2]

Yeah but the collagen side effects are the worse that's been reported. You're not gonna get a higher heart rate, chest pain, lower blood pressure, or dizziness with bimataprost. If it could be brought down to the price of minoxidil, why should we even use minoxidil anymore?

Virtually no one gets those things from topical minoxidil. Any doctor would tell you that someone who claims they do is actually suffering from nocebo and anxiety

You would use minoxidil because if you're in the 40% that responds well to minoxidil you'll get better results than with bimatoprost. Head to head minoxidil and bim had roughly the same increase in hair counts overall, but minoxidil gives a greater increase in hair count for top responders because the distribution isn't as even as it is for bim. For some people bim is better while for others minoxidil is better.

 

[RoySmith]

Virtually no one gets those things from topical minoxidil. Any doctor would tell you that someone who claims they do is actually suffering from nocebo and anxiety

You would use minoxidil because if you're in the 40% that responds well to minoxidil you'll get better results than with bimatoprost. Head to head minoxidil and bim had roughly the same increase in hair counts overall, but minoxidil gives a greater increase in hair count for top responders because the distribution isn't as even as it is for bim. For some people bim is better while for others minoxidil is better.

Gotcha, I heard some people get migraines from minoxidil too. Anyway, being able to add bimataprost to a regimen gives us more options and that's one of the main reasons people keep checking the new technologies section here. Remember the Brotzu lotion fiasco?

 

[pegasus2]

Gotcha, I heard some people get migraines from minoxidil too. Anyway, being able to add bimataprost to a regimen gives us more options and that's one of the main reasons people keep checking the new technologies section here. Remember the Brotzu lotion fiasco?

Like I said, people already get bim cheap from Alibaba. I use dinoprost which is the same thing and even cheaper. I understand your friend wants to make some money, but he already has competition. This is nothing new.

 

[trialAcc]

Like I said, people already get bim cheap from Alibaba. I use dinoprost which is the same thing and even cheaper. I understand your friend wants to make some money, but he already has competition. This is nothing new.

Would you recommend that the average person look into bim and dinoprost if they respond poorly (not at all) to topical min? I think I mentioned to you in the SM thread that I was a complete non-responder to topical min.

 

[pegasus2]

Would you recommend that the average person look into bim and dinoprost if they respond poorly (not at all) to topical min? I think I mentioned to you in the SM thread that I was a complete non-responder to topical min.

Yes, either that or adenosine. Shiseido sells the latter under the brand name Adenogen. It's comparable to minoxidil, but doesn't require sulfotransferase to activate it.

 

[RoySmith]

Like I said, people already get bim cheap from Alibaba. I use dinoprost which is the same thing and even cheaper. I understand your friend wants to make some money, but he already has competition. This is nothing new.

I'm glad you mentioned that. It's listed on Alibaba for $4 a bottle for the eyelash growth bottle that Latisse uses. Never knew that. I may stock up soon.

 

[Will Be an Egg in 5 years]

Why hasn't it been tested for Androgenetic Alopecia?

 

[Janks16]

I used it for 3 years in order to get thicker eyebrows, and also tried it on my hair, but it didn't do anything for me.

 

[Chromeo]

Allergan tested it in 2011 for scalp hair loss. Results were poor.

 

[pegasus2]

Allergan tested it in 2011 for scalp hair loss. Results were poor.

That was bimatoprost, and results weren't poor they were equivalent to minoxidil

 

[nick123]

It's efficacy is pretty much comparable to Minoxidil, they also cross over on a number of there mechanism of actions except Latanoprost/Bimatoprost/Dinoprost is better at upregulating FGF7.

 

[Dimitri001]

I'm kinda surprised more people don't decide not to use minoxidil because of the collagen thing. I mean, if the choice is being a bit balder or having your face aged, I figure most people would go for the former.

But I'm also surprised minoxidil's collagen effect WOULD affect your face, since you apply it to your scalp. I mean, I know it goes systemic, but...

Yes, either that or adenosine. Shiseido sells the latter under the brand name Adenogen. It's comparable to minoxidil, but doesn't require sulfotransferase to activate it.

Is there anything that works by the same mechanism that doesn't have the collagen side effect?

 

[pegasus2]

I'm kinda surprised more people don't decide not to use minoxidil because of the collagen thing. I mean, if the choice is being a bit balder or having your face aged, I figure most people would go for the former.

But I'm also surprised minoxidil's collagen effect WOULD affect your face, since you apply it to your scalp. I mean, I know it goes systemic, but...


Is there anything that works by the same mechanism that doesn't have the collagen side effect?

Estrogen and anything that acts directly on Wnts downstream of prostaglandins, such as KY or WAY.

I don't think that the effect of topical minoxidil is that bad on your face if you don't let it run down your face. It doesn't really go systemic unless you apply it with DMSO, or if you use too much. I only noticed it when I was on OM and when I was using topical minoxidil 4+ times a day

 

[trialAcc]

Estrogen and anything that acts directly on Wnts downstream of prostaglandins, such as KY or WAY.

I don't think that the effect of topical minoxidil is that bad on your face if you don't let it run down your face. It doesn't really go systemic unless you apply it with DMSO, or if you use too much. I only noticed it when I was on OM and when I was using topical minoxidil 4+ times a day

You used topical min 4x daily? Did you see results?