Best way to deal with depression:
# psychotropic medication: Most effective antidepressants are the irreversible non-selective MAOI: Nardil, Parnate (Seligiline to some degree). Also quite good: tricyclic antidepressants, especially Clomipramine and Amitriptyline. Combination therapy, e.g. Sertraline + Nortriptyline, can be quite good.
# Psychotherapy, Mindfulness, muscle relaxation
# You should have regular sleep, meals, sports and so on.
# Wake the demon inside you. Don't be too nice (listen to Jordan Peterson!)
# Analyze your situation, be honest with your analysis, implement changes.