Where to buy sulfasalazine

[Bagels]

I've looked all over, but can't find a decent place to buy this online. Please help

 

[Soviet Youth]

You need a prescription.

 

[Dench57]

Inhouse Pharmacy

 

[Parsia]

For sulfasalazine , Inhouse pharmacy is best plus last time I have checked they ship free to U.S .

For others like finasteride, dutasteride And etc , Alldaychemist always have the best and cheapest price .

 

[Norwood One]

Any side effects you guys know of? How safe it it? This could be great for people that can't afford Seti yet.

 

[Swoop]

Inhouse. That said why do you want to use it? It's totally useless for your hair lol.

 

[Dench57]

Inhouse. That said why do you want to use it? It's totally useless for your hair lol.

What makes you think Sulfasalazine is useless for hair? It increases PGE2, decreases PGD2, and inhibits a number of pro-inflammatory and hair-inhibiting factors that are overexpressed in balding scalp (TGF-b, TNF-a, IL6, NF-Kb to name a few).

 

[Swoop]

What makes you think Sulfasalazine is useless for hair? It increases PGE2, decreases PGD2, and inhibits a number of pro-inflammatory and hair-inhibiting factors that are overexpressed in balding scalp (TGF-b, TNF-a, IL6, NF-Kb to name a few).

It's pretty much a fact. Look, many thousands of people have been or are on sulfasalazine. Among those thousands of people enough people are suffering from Androgenetic Alopecia. I'm fairly sure you know how prevalent Androgenetic Alopecia is in humans. I define it as "useless" because it doesn't grow your hair back. It doesn't act as a hair growth agent treatment neither does it act as a maintenance treatment. So even if it works upon these factors you mention what does that matter? We can see from people that use it that it doesn't do anything for Androgenetic Alopecia. If it would do anything people would notice that. Honestly it would have already been shown years ago in the clinical trials. To think otherwise is just a joke. I don't see how a rational person couldn't agree with this? Yes there is one guy on a forum that claimed that his hairline regrew with using sulfasalazine. But if we are to take every anecdotal experience seriously I might just as well be rubbing "natural" treatments on my head with the "hope" that it will stop my progression of Androgenetic Alopecia.

 

[whatevr]

That's because it's not supposed to regrow hair on its own. It can act as a cornerstone of a regimen with other things. There is no magic, one-pill, silver bullet solution for baldness. It has to be attacked from varying angles, I think that much is becoming clear by now. Until we can put all the right agonists and antagonists into a single pill or topical formula, there will not be a 'single' thing against baldness. So it's misguided to expect this from any compound unless specifically formulated as such.

 

[Dench57]

It's pretty much a fact.

lol

Look, many thousands of people have been or are on sulfasalazine. Among those thousands of people enough people are suffering from Androgenetic Alopecia. I'm fairly sure you know how prevalent Androgenetic Alopecia is in humans. I define it as "useless" because it doesn't grow your hair back.

All its going to do is reduce inflammation and slow down hairloss at best. You think something like that is going to be picked up in clinical trials for arthritis or crohn's disease? Your definition of useless is obviously different to mine... I don't expect every single treatment to drastically regrow hair. As the poster above me said, with these experimental/alternative approaches, there is no silver bullet, you have to address so many different factors. We're never going to get a clinical study on Sulfasalazine's effects on Androgenetic Alopecia, so all we have to work on is theory and anecdotes. The theory makes sense. And all the anecdotes I've heard say it reduces scalp inflammation, sebum/itch and soreness, and hair looks and feels healthier. Conclusive? No. A cure? No. But I don't think its completely useless.

 

[Swoop]

All its going to do is reduce inflammation and slow down hairloss at best. You think something like that is going to be picked up in clinical trials for arthritis or crohn's disease? Your definition of useless is obviously different to mine... I don't expect every single treatment to drastically regrow hair. As the poster above me said, with these experimental/alternative approaches, there is no silver bullet, you have to address so many different factors. We're never going to get a clinical study on Sulfasalazine's effects on Androgenetic Alopecia, so all we have to work on is theory and anecdotes. The theory makes sense. And all the anecdotes I've heard say it reduces scalp inflammation, sebum/itch and soreness, and hair looks and feels healthier. Conclusive? No. A cure? No. But I don't think its completely useless.

Off course it's not going to get picked up in a clinical trial because it doesn't do sh*t for hair. If it would do actually something it would get picked up as a side effect. But it didn't, not only in clinical trials but by thousands of people.

I think you put to much emphasis on anecdotal experience. Why don't you buy a laser cap? Enough anecdotal evidence that it works to some extent. Why don't you rush for some PRP injections Dench? Some anecdotal experience also tells us that it works to some extent. Even better both those treatments have double blind controlled placebo clinical trials behind them. Yet how would you classify these treatments overall Dench? Would you define them "useless" ? I guess not then? You would probably say they are not "completely useless"? What does that even mean..?

Our definitions of "useless" are clearly different I guess. I hate to break your bubble but all these experimental treatments till date have brought sh*t all. The best results are still achieved by either compounds that modulate androgen expression or antagonize the androgen receptor. Besides that we have minoxidil as a hair growth agent pretty much.

So you think there is no silver bullet. Ok, so we need to "address" multiple factors... Well if you think that and want to do that, that's completely fine. But where are the pictures? Where can I see the regrowth? I haven't seen one picture of someone using experimentals that can match itself with someone who responds well to minoxidil or finasteride. Even if he uses a plethora of experimentals. You'll be literally a walking apothecary with minimal results to show. Is that a success?

I guess it indeed all boils down to what one's definition of a worthfull treatment is. I mean some people are happy with rubbing natural stuff on their scalp or massaging their head with a boar bristle brush right? Speaking of scalp massage, do know that on the hair congress there is a study of someone that shows that massaging the scalp increases hair thickness in humans?

P123 Standardized scalp massage results in increased hair thickness" Taro Koyama, MD, PhD | Japan

You get my point now. In the case of OP off course I will tell him that sulfasalazine is useless. If I tell him its a worthfull treatment then I might just as well start telling people that massaging your scalp or PRP is a worthfull treatment.

If someone does however manage to fix some sort of regimen that does create good results with the inclusion of sulfasalazine which is necessary then we would be talking differently. The only pictures I saw thus far though is from someone that regrew some peach fuzz in a NW1.5 area. Nobody else provided pictures. Too much talk, not much results to show.. At least till now. I hope that will change but till that point I'm not going to be delusional. Time will tell.

 

[Bad]

I cant find it on inhouse :s

 

[Parsia]

Off course it's not going to get picked up in a clinical trial because it doesn't do sh*t for hair. If it would do actually something it would get picked up as a side effect. But it didn't, not only in clinical trials but by thousands of people.

I think you put to much emphasis on anecdotal experience. Why don't you buy a laser cap? Enough anecdotal evidence that it works to some extent. Why don't you rush for some PRP injections Dench? Some anecdotal experience also tells us that it works to some extent. Even better both those treatments have double blind controlled placebo clinical trials behind them. Yet how would you classify these treatments overall Dench? Would you define them "useless" ? I guess not then? You would probably say they are not "completely useless"? What does that even mean..?

Our definitions of "useless" are clearly different I guess. I hate to break your bubble but all these experimental treatments till date have brought sh*t all. The best results are still achieved by either compounds that modulate androgen expression or antagonize the androgen receptor. Besides that we have minoxidil as a hair growth agent pretty much.

So you think there is no silver bullet. Ok, so we need to "address" multiple factors... Well if you think that and want to do that, that's completely fine. But where are the pictures? Where can I see the regrowth? I haven't seen one picture of someone using experimentals that can match itself with someone who responds well to minoxidil or finasteride. Even if he uses a plethora of experimentals. You'll be literally a walking apothecary with minimal results to show. Is that a success?

I guess it indeed all boils down to what one's definition of a worthfull treatment is. I mean some people are happy with rubbing natural stuff on their scalp or massaging their head with a boar bristle brush right? Speaking of scalp massage, do know that on the hair congress there is a study of someone that shows that massaging the scalp increases hair thickness in humans?



You get my point now. In the case of OP off course I will tell him that sulfasalazine is useless. If I tell him its a worthfull treatment then I might just as well start telling people that massaging your scalp or PRP is a worthfull treatment.

If someone does however manage to fix some sort of regimen that does create good results with the inclusion of sulfasalazine which is necessary then we would be talking differently. The only pictures I saw thus far though is from someone that regrew some peach fuzz in a NW1.5 area. Nobody else provided pictures. Too much talk, not much results to show.. At least till now. I hope that will change but till that point I'm not going to be delusional. Time will tell.

Swoop, I always respect you as a nice person but I have to clear something on here.

although I agree with you about the definition people use in the world are different like Useless...Spam...etc..

But You can't blame these guys ( include me ) to try experimentals even though you don't see any picture so far....Its experimental..

.what do you expect?

Let me ask you something..even if you're golden treatment is minoxidil...Does it any research about minoxidil 15 % ?

Do you have any document to show me it has better result? Is it safe when it comes to side effect ? Would you please show me some pics?

The answer is NO.

But I have used it in the last couple months and get better result....I just made an example of minoxidil to get better understanding on

here.

And please tell me when was the last treatment that approved by FDA ? does anybody remember? Oh we didn't have anything for more

than 15 years...

and just those two Minoxidil and Finasteride...Good job all doctors in the world... your help is much appreciated..Keep doing what you doing

because you are going to make it..!!

we can't wait for this retard world and just go to walmart and buy Generic minoxidil 5 % with alcohol and expect our hairs to regrow....

Its not fair if you blame us to try to do something more...If you didn't see the pictures that doesn't mean none of them are working..

Minoxidil is not working for everyone..So if you just pick up the well responded minxoidil pics and compare that with those who use

experimental..its not fair...And I also like to mention the people who are using experimental...are in minority...People in real life

using minoxidil or finasteride ..The people on forums...especially this forum Most likely using the big 3...So the amount of documents to show

you the experimental MAY work is limited...So comparison will not be fair.

if the DHT was a reason for hairloss by now we all should have full head of hair.. We even don't know how the minoxidil works...( We don't

know the details according to the minoxidil makers ) ..

It has discovered SUDDENLY .. Please pay attention to the word of suddenly....So how can we know if we don't find any other treatment (

in the worst situation suddenly and no knowledge ) to help our hairloss?

even the result would be great or we failed that doesn't change anything... we just trying to do the jobs that the world doesn't care....

We just trying to do not limited ourself about TWO limited options that DEAR FDA gift to us.

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I cant find it on inhouse :s

I have looked that for you .They don't have that by now...They have a generic one...and its pricey..

Look at alldaychemist website...Right now their prices are cheaper.

 

[Swoop]

@Parsia, I don't blame anyone for trying experimental(s). Where do you see me stating that? Do whatever makes you happy. That doesn't mean that I'm going say that sulfasalazine is worth it. Hell no, I will call it useless. Cause that is what I think it is. If I would call it worthfull I might just as well say that treatments like PRP, LLLT etc. are worth it. If OP or anyone else wants to proceed anyway that is his decision. If anything he will learn himself if the treatment is worth it for himself.

It's funny that you mention minoxidil has worked better for you in a higher concentration. Indeed a treatment that till date is unmatched. Several (multi million) companies have tried to outperform minoxidil, but nobody succeeded (even while minoxidil has a pretty low response rate like you mention). Is it pathetic that we don't have a better growth treatment than stone-age minoxidil? Jup. But it is what it is.

I watched your topic on your personal success. Nice, you seem to have a bit cosmetic benefit and stabilization. But what are your treatments that made this happen Parsia? Pretty sure it's finasteride and potent formulations with minoxidil, not? You didn't do it with some experimental(s) did you? Try dropping your current regimen and switch it with a experimental "regimen" that covers "all angles". I challenged you to do that right? Let's see how your hair will fare under that. Probably not very good

Obviously you want to regrow your hair line and you try to do this with experimental(s). I wish you all the best. I hope you succeed. My honest thoughts? It's most likely not going to happen. Please do prove me wrong though. And off course I want to see pictures or studies Parsia. If CB-03-01 comes out with their results soon I assume you want to see pictures or data, not anecdotal evidence of a few simple words? Also, if a regimen that covers all "angles" (whatever that is) would really work in regrowth then people would be showing off mate. Everyone would be posting his pictures here showing his incredible success. Even if it is a small group of people. I haven't seen it yet.

 

[Dench57]

Off course it's not going to get picked up in a clinical trial because it doesn't do sh*t for hair. If it would do actually something it would get picked up as a side effect. But it didn't, not only in clinical trials but by thousands of people.

It's not going to get picked up in trials because Sulfasalazine alone is not going to maintain your hair, let alone regrow. I just believe it can be helpful in slowing male pattern baldness by inhibiting a number of inflammatory mediators that are overexpressed in balding scalp as a direct result of DHT.

I think you put to much emphasis on anecdotal experience. Why don't you buy a laser cap? Enough anecdotal evidence that it works to some extent. Why don't you rush for some PRP injections Dench? Some anecdotal experience also tells us that it works to some extent. Even better both those treatments have double blind controlled placebo clinical trials behind them. Yet how would you classify these treatments overall Dench? Would you define them "useless" ? I guess not then? You would probably say they are not "completely useless"? What does that even mean..?

Haha. Purely expense. The general consensus (anecdotal?) of PRP is that its slightly helpful, but not enough to justify the cost. If it was the same price as Sulfasalazine, I'm sure I would have used it. If we're talking strictly efficacy and not safety of course, because Sulfa is not safe for everyone but thats a different debate.

Our definitions of "useless" are clearly different I guess. I hate to break your bubble but all these experimental treatments till date have brought sh*t all. The best results are still achieved by either compounds that modulate androgen expression or antagonize the androgen receptor. Besides that we have minoxidil as a hair growth agent pretty much.

So you think there is no silver bullet. Ok, so we need to "address" multiple factors... Well if you think that and want to do that, that's completely fine. But where are the pictures? Where can I see the regrowth? I haven't seen one picture of someone using experimentals that can match itself with someone who responds well to minoxidil or finasteride. Even if he uses a plethora of experimentals. You'll be literally a walking apothecary with minimal results to show. Is that a success?

I'm not arguing with you that compounds that either inhibit DHT or antagonise the androgen receptor are the best we have. I agree 100%. I'm pretty certain that nobody using experimental compounds will be able to match the good responders to Finasteride and minoxidil. I don't think anyone is making those claims. But this is the "Experimental" section. People are trying this stuff because the traditional treatments hasn't worked for them, or has given them intolerable side effects, or any other reason. Right now there is nothing to suggest experimental treatments will match the traditional treatments but what do you expect those of us who can't use traditional treatments to do? Sit in the Impact section and cry about how life is hard going bald? Speaking for myself but **** that. Not until I've exhausted every other avenue. Within reason of course - I'm sure I could take 200mg spironolactone a day and be golden. But I'm not there yet.

If someone does however manage to fix some sort of regimen that does create good results with the inclusion of sulfasalazine which is necessary then we would be talking differently. The only pictures I saw thus far though is from someone that regrew some peach fuzz in a NW1.5 area. Nobody else provided pictures. Too much talk, not much results to show.. At least till now. I hope that will change but till that point I'm not going to be delusional. Time will tell.

I assume you're referring to the now semi-infamous "PG Protocol" and I agree that it doesn't really mean **** until we see numerous users showing photo evidence. You keep asking for photos of regrowth but nobody else has actually been implementing the same regimen that SwissTemples has, hence the lack of photos. I'll be giving that a full crack when I get all the necessary materials and will be posting a log on here so you can have a good laugh at me . If it doesn't work at all, then **** it I'll just bite the bullet and take Dutasteride, get a transplant, or take spironolactone lol. Personally I don't think any "PG protocol" will work to full effect without 5ARi or AA but would love to be proved wrong.

But anyway, back to the original point. We obviously have different interpretation of the words "useless" and "delusional". I don't think Sulfasalazine is useless, and I don't think I or most of the other "experimental" people are delusional to expect there may be a new angle to hairloss, using the knowledge and theories outlined in the Cots/Gho/Garza papers, and putting that knowledge into practice. If people expect to regrow a teenage hairline with it then yes - they're delusional. I don't expect much at all with it, I'm fairly well grounded in the reality of our situation - that 5ARi/AA is the gold standard for treating male pattern baldness. Will be for a long time. But I disagree with you calling it "useless", or calling people "delusional" for trying what I believe to be a reasonable approach that is grounded in, to my eyes, pretty promising scientific theory.

 

[Bagels]

In house pharmacy has the best price buy the only take E check and want bank info (new policy) Seems VERY risky. Anyone with experience or alternatives?

 

[username425]

Did echeck. It's fine. Inhouse is trusted.

 

[Swoop]

@Dench57. Well we actually seem to agree on many things then . And, yes perhaps sulfasalazine can slow male pattern baldness somewhat. I see no proof for that, but it's possible. You know what slows male pattern baldness? 17a-estradiol (alfatradiol). Yet it's considered weak as hell and not worth anyone his time. Or maybe pumpkin seed oil? Get my point? That's why I call sulfasalazine useless, and that's why I will continue to call it useless.

I get it though it must suck horribly if you can't use traditional treatments due to side effects. Or it sucks horribly if you want that regrowth that traditional treatments don't give you with the “hope” that some experimental(s) will. I don't agree on the part that traditional treatments don't work. I guess it depends how hard you hit the androgen/androgen receptor angle. If you hit it hard enough for example with dutasteride + a strong androgen receptor antagonist (although AR antagonists ain't really traditional treatments) then it will work for nearly everyone. Without androgens or without androgen receptor activity Androgenetic Alopecia stops progressing. It's that simple. Sure they won't always please everyone in terms of regrowth. That's why it's crucial to prevent the damage from happening. Nonetheless if it's due to side effects or other possible reasons yes then it's a very hard life to deal with Androgenetic Alopecia. You'll be immediately looking at sub-par treatments. Treatments that will very often lead to disappointment generally. But indeed, doing something is better than doing nothing I guess.

That was indeed a reference to him. Off course it doesn’t mean anything and I’m glad you understand that. Fast forward from now it will most likely lead to huge disappointment too. I can already smell and see that it will probably become a failure. We'll see though, good luck with it. Prove me wrong I would say. I hope you achieve whatever you are looking for.

Indeed, I guess it's just a different interpretation like you mention. I never said anyone is delusional, I said I am not going to be delusional. I want better evidence whether that is for some sort of protocol or a single compound, it doesn't matter. Simple as that. Till now I see sh*t results or only very weak anecdotal experience.

Sure, there might be a other good angle to hair loss. Maybe setipiprant will happen to be just that, at this point it's nothing more than a hypothesis though. Remember I also didn't call setipiprant useless, I called sulfasalazine useless. I still think that DP2 antagonizing won't come close to something like finasteride. This is simply my view primarily based on papers and opinions from other researchers. It's speculation though. I would happily switch over to setipiprant to maintain my hair. Probably never going to happen imo but we’ll see.

All in all Androgenetic Alopecia is a b*tch mate. Many things can't be sugar coated. Oh and please don't take spironolactone man lol.

 

[Parsia]

@Parsia, I don't blame anyone for trying experimental(s). Where do you see me stating that? Do whatever makes you happy. That doesn't mean that I'm going say that sulfasalazine is worth it. Hell no, I will call it useless. Cause that is what I think it is. If I would call it worthfull I might just as well say that treatments like PRP, LLLT etc. are worth it. If OP or anyone else wants to proceed anyway that is his decision. If anything he will learn himself if the treatment is worth it for himself.

It's funny that you mention minoxidil has worked better for you in a higher concentration. Indeed a treatment that till date is unmatched. Several (multi million) companies have tried to outperform minoxidil, but nobody succeeded (even while minoxidil has a pretty low response rate like you mention). Is it pathetic that we don't have a better growth treatment than stone-age minoxidil? Jup. But it is what it is.

I watched your topic on your personal success. Nice, you seem to have a bit cosmetic benefit and stabilization. But what are your treatments that made this happen Parsia? Pretty sure it's finasteride and potent formulations with minoxidil, not? You didn't do it with some experimental(s) did you? Try dropping your current regimen and switch it with a experimental "regimen" that covers "all angles". I challenged you to do that right? Let's see how your hair will fare under that. Probably not very good

Obviously you want to regrow your hair line and you try to do this with experimental(s). I wish you all the best. I hope you succeed. My honest thoughts? It's most likely not going to happen. Please do prove me wrong though. And off course I want to see pictures or studies Parsia. If CB-03-01 comes out with their results soon I assume you want to see pictures or data, not anecdotal evidence of a few simple words? Also, if a regimen that covers all "angles" (whatever that is) would really work in regrowth then people would be showing off mate. Everyone would be posting his pictures here showing his incredible success. Even if it is a small group of people. I haven't seen it yet.

Since your respond was respectfully , I am going to answer you in a respect manner as well.
Swoop I personally like these arguments , there is nothing wrong with that... We just share our brain storms and it will also help the community to have better understanding of different treatments as long as we respect to each other...
Regards to PRP , LLLT ..As Dench mentioned we judge the result by the price..Sulfa is pretty cheap..If you know which source you should use..
About my better result with minoxidil 15 % ..I was waiting that you challenge me with that...So I didn't get surprise..I knew you would use it against of me..Lol..

But I just like to mention some part of my result could be because of Proxiphen (Which is completely Experimental..If you know the ingredients of that you won't make up the argument that it has 2 % minoxidil in it..because its not minoxidil base formula ) For Minoxidil 15 % lotion I just like to add that it has some other additives as well like Finasteride ,Azelaic acid,Tretinoin , Hydrocortisone , Progesterone ,Vitamin E and DMI .. But I agree its Minoxidil base formula..And I personally think Minoxidil 15 % SHOULD work better than 5 % , at least on the paper.

And the result I've got so far...in a one year course ..Is not great..But I've got regrowth in some degree and my hairline pushing forward..But the result hasn't satisfied me as you mentioned.. So I am going to try my best.. Am I getting my hairline back ? I really " Don't know " .. and If I wouldn't get my result in the next year or two..I will definitely go for hair transplant and accept your theory .. Its too soon to say which of us are right.. as you know we should wait and see.. Time will tell.. and there is nothing wrong with that you do not think like me..I just asked you to do not disappoint the guys who want to try new things..this section is belong to Experimental ..So don't expect people to come and talk about DEAR BIG3

And no I will not drop the traditional treatment because as you mentioned we have to use AA to battle hairloss.. But I THINK we need to cover other angles as well to get better result.. Again...It was good that we challenged each other and sometimes it helps us and community.
Good luck.

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What makes you think Sulfasalazine is useless for hair? It increases PGE2, decreases PGD2, and inhibits a number of pro-inflammatory and hair-inhibiting factors that are overexpressed in balding scalp (TGF-b, TNF-a, IL6, NF-Kb to name a few).

I really like your post because the way you look at that is realistic..You don't get too excited about the experimental and you do not be against of traditional treatment.
the way you see the facts here looks neutral and I think me and you are on the same page.. glad to have you here .

 

[Swoop]

@Parsia, Off course you won't drop it. Because there is a extremely high chance when you will drop finasteride+minoxidil your hair will get shredded fast. It's logical.

By the way if the hypothesis of Kythera is correct there is no need for any compound that modulates androgens or the androgen receptor. You simply could get away with a very strong DP2 antagonist and maintain your hair just as well as current maintenance treatments do and probably better seeing the strong DP2 antagonists we have. It's simply a chain. Androgens > AR function upstream, confirmed and a fact. If you either remove androgens or AR, Androgenetic Alopecia can't persist. If the hypothesis of Kythera is correct this would make the chain; Androgens > AR > PTGDS> PGD2 > DP2 >>>> hair loss. So when you would strongly antagonize the DP2 receptor there would be no need for finasteride. That's why I challenged you to drop the finasteride. Similarly by the way when you would remove all androgens or AR there is no need for reducing PGD2 levels or antagonizing the DP2 receptor. That is if we are looking purely at their hypothesis.

You say that it's too soon if I'm right. When someone goes and buys a lottery ticket I can't know for 100% either if he wins it or not. After all he could win it, but the chances are almost non-existent. It gets rather easy to predict certain things. Good luck anyway!