zzzzz's 1 year dutasteride results

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Eightballd

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Hey zzzzz how much would you attribute dutasteride to your regrowth, I don't really want to hop on minoxidil even though I bought a 3 month supply since it's just a hassle IMO since you can't part with it, also are you aware?
 
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zzzzz

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Eightballd said:
Hey zzzzz how much would you attribute dutasteride to your regrowth, I don't really want to hop on minoxidil even though I bought a 3 month supply since it's just a hassle IMO since you can't part with it, also are you aware?
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I don't know honestly for my individual situation. While I think dutasteride is the most important by far for long term maintenance of hair, if regrowth is your goal really minoxidil should be used. You should really read this:

and yes I am aware

For quite some time now, I've been telling people that from my reading of various topical minoxidil studies and finasteride studies, it appears that minoxidil is more effective at stimulating regrowth than finasteride; an obvious question nowadays would be: where does the very long-awaited dutasteride fit into the grand scheme of things? We have some good data from the dutasteride phase II trial, so does it finally surpass what Rogaine can do? I decided to look at the data from every topical minoxidil study in my collection and make an objective comparison! Since the only reported data in the dutasteride trial were the hair-counts, I could only use minoxidil studies that also reported hair-counts, to get any kind of meaningful comparison; and there are exactly six of them in my collection.

I've given the full citations to the studies at the very end of this post, in case anyone wants to double-check my figures and computations. As I'm reporting the numbers for each one, I'll just refer to them as (1) through (6)...again, you can check at the end to see the full reference. The minoxidil studies lasted for varying lengths of time like 4 months, 6 months, and 12 months, while the Glaxo finasteride and dutasteride trial lasted only for six months; to compensate for that, I've specified the actual length of each individual trial, and then calculated the hair-count increase PER MONTH, for fairness. Also, all hair-counts are standardized to the familiar 1-inch circular test spot on the scalp. Ok...all set? Here we go:

(The Glaxo trial of finasteride and dutasteride)

Finasteride... +72 hairs, six months (12.0 hairs/month)
Dutasteride... +108 hairs, six months (18.0 hairs/month)

(All the following are the topical minoxidil studies)

(1) 2% minoxidil... +425 hairs, 12 months (35.4 hairs/month)
Also: 3% minoxidil... +372 hairs, 12 months (31.0 hairs/month)

(2) 2% minoxidil... +273.4 NONVELLUS hairs, 12 months (22.8 hairs/month)

(3) 2% minoxidil... +101 TERMINAL hairs, 13 months (7.8 terminal hairs/month)

(4) 1% minoxidil... +149 hairs, 6 months (24.8 hairs/month)
Also: 2% minoxidil... +175 hairs, 6 months (29.2 hairs/month)

(5) 2% minoxidil... +233.8 hairs, 12 months (19.5 hairs/month)

(6) 2% minoxidil... +151 hairs, 4 months (37.8 hairs/month)
Also: 2% minoxidil... +324 hairs, 12 months (27 hairs/month)
Also: 3% minoxidil... +166 hairs, 4 months (41.5 hairs/month)
Also: 3% minoxidil... +338 hairs, 12 months (28.2 hairs/month)


There you have all the data! Averaging all the topical minoxidil data shows an average hair-count increase of +25.1 hairs per month (for that study #6, I'm using just the 12-month data), whereas dutasteride only managed a hair-count increase of +18.0 hairs per month! Finasteride brings up the rear at only +12.0 hairs per month! Summarizing the data is very simple and elegant: dutasteride generates about 50% more regrowth than finasteride (we've been saying that for a long time), and topical minoxidil generates about 50% more regrowth than dutasteride, according to all these studies! And here's a small but important detail: the minoxidil hair-counts are actually a little UNDERestimated, because the numbers reported for studies #2 and #3 were for nonvellus and terminal hairs, respectively. Factoring in TOTAL hair-counts (which weren't reported in those two studies) would make regrowth from topical minoxidil even more impressive.

Bottom line: as I've been saying for a long time, dutasteride is a fine new addition to our weaponry, but it should be considered a potent agent to inhibit the balding process itself, and not really something that's going to stimulate a lot of extra regrowth. For that, you'll have to use a complete program that addresses all the known angles that we've been talking about, like minoxidil, SODs, etc. By no means is dutasteride all by itself any kind of ultimate "cure" for balding; at least, not if any serious regrowth is one of your goals. But if all you need to do is maintain, then it should be an outstanding new drug for you, even by itself.

Bryan
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Quantum Cat said:
haven't had any unwanted sides from dutasteride, zzzzz? fatigue or anything?
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no
 
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Eightballd

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That study is real nice and tempting but then I think about how irritating it would be applying it IRL. Anyone ever apply minoxidil once a week or something ? Also if I apply minoxidil in a specific area those hairs that form there or regrow are now all minoxidil dependent right? Anyone ever drop minoxidil while on dutasteride or w/e to see if they do really drop back to baseline? I really just want my temples / hairline to regrow I'm not a diffuser so I don't think I need minoxidil as much as some people
 
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zzzzz

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Eightballd said:
That study is real nice and tempting but then I think about how irritating it would be applying it IRL. Anyone ever apply minoxidil once a week or something ? Also if I apply minoxidil in a specific area those hairs that form there or regrow are now all minoxidil dependent right? Anyone ever drop minoxidil while on dutasteride or w/e to see if they do really drop back to baseline? I really just want my temples / hairline to regrow I'm not a diffuser so I don't think I need minoxidil as much as some people
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dutasteride will not save minoxidil-induced growth. You can take it once daily, but I would not take it any less than that
 
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randomusername

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I'm about to hit my 8 month mark with finasteride, I haven't noticed a decrease in hair loss and it seems like my hair loss has accelerated in the past couple of weeks. I've been on minoxidil since May and haven't really noticed much, I have some newer hairs around the temples but nothing going terminal. I'm going to give this a little while longer, I'll try to hit 1 year on finasteride but the lack of results is very discouraging right now. And I do nizoral about 1-2 times a week. I'm thinking I'll try it every other day now.

Anyways, do you have a script for dutasteride? If not do you know a good website to get some? Price wise is it a lot cheaper getting a script as opposed to getting some online like it is for finasteride?
 
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Nadester

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Some questions from me:-
1.Did you have any facial hair BEFORE starting dutasteride
2.If yes then how is it now??
Thank you.Hope you grow more:smile:
 
zzzzz

zzzzz

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Nadester said:
Some questions from me:-
1.Did you have any facial hair BEFORE starting dutasteride
2.If yes then how is it now??
Thank you.Hope you grow more:smile:
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1. Yes, full beard growth
2. It's the same
 
SayifDoit

SayifDoit

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Zzzzz I'm sure you've answered this question but what is your family history of male pattern baldness, also perhaps condition of brothers hair?
 
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DFWdesperado

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Congrats on the progress OP, looks much improved! Where can you get dutasteride from? And where could I go to find out more about it? Havent seen any info/reviews anywhere on here, but I did just join yesterday
 
zzzzz

zzzzz

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Plan C said:
Do you feel taking dutasteride every day has affected your cognitive function since you started?
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no

Zzzzz I'm sure you've answered this question but what is your family history of male pattern baldness, also perhaps condition of brothers hair?
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all uncles, father, and grandfather are nw1. Other died nw2 or 3 at 50

Congrats on the progress OP, looks much improved! Where can you get dutasteride from? And where could I go to find out more about it? Havent seen any info/reviews anywhere on here, but I did just join yesterday
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inhousepharmacy.vu and pay with echeck. For info on dutasteride vs. finasteride look at this http://www.bernsteinmedical.com/resources/hair-restoration-papers/dutasteride-vs-finasteride/
 
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bluesuedeshoes

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How has the itch been zzzz? Really interested in that you regrew while the itch was still present. I always assumed that if mine was still bad then whatever I was using wasnt working. Reassuring to know that it's still poss to get regrowth with it still raging.
 
eenrak

eenrak

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If you read zeroheats story you will see that he got amazing regrowth despite massive itching.

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If you read zeroheats story you will see that he got amazing regrowth despite massive itching.
 
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