Actual picture of the biodegradable scaffold Stemson is using for hair cloning

werefckd

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Isn't Stemson is ahead of Tissuse? I am waiting for Follica and Samumed, should be the closest one, and maybe RCH01.
Tissuse stoped their "Smart Hair Transplant" research and erased every mention of in their website a long time ago. And J Hewitt doesn't even have a website.

Do they look like they will be the ones curing baldness? Lol

(Edit: added the word research)
 
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werefckd

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This technology is at least 10-15 years away. We must live in reality, not in fantasy world. And the main question is how much it will be successful.
It could be 5 years away, or 10-15 years away, or 100 years away. No way to be sure.

It sucks to be waiting for something that may never come. That's why if you are NW6 or under, have good hair characteristics and donor area, you should be SERIOUSLY considering the hair transplant alternative and researching good doctors.

Currently, and for many years in the future, the only thing that is potentially able restore your head is hair transplants.

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werefckd

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please stop presenting your opinion as a fact.
tissuse is still working on it, they are currently even working on regrowing teeth. That is also not on their website.
There they are currently in the preclinical phase.
1. Tissuse stoped working on SHT
2. They erased the SHT section from their website
3. J Hewitt doesn't have a website

These are not my opinions. These are simple, verifiable facts.
 

werefckd

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Not a conclusion. I ended my post with a question: "Do they look like they will be the ones curing baldness?". It's up to you all to draw you own conclusions.
 

werefckd

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stopped and (...)
are two things, one is true, the other is not. Tissuse could restore a lot of hair. The research is very promising, including the study that was published this year. The trial will start in 2021 and then we will know more. But stop saying that the research has stopped. Because its not true. (official statement from Tissuse)

Incidentally, if the studies are promising, further studies will take place in Europe immediately in the following year
They stoped their Smart Hair Transplant research and took the section out of their website.
 

pegasus2

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It could be 5 years away, or 10-15 years away, or 100 years away. No way to be sure.

It sucks to be waiting for something that may never come. That's why if you are NW6 our bellow, have good hair characteristics and donor area, you should be SERIOUSLY considering the hair transplant alternative and researching good doctors.

Currently, and for many years in the future, the only thing that is potentially able restore your head is hair transplants.

View attachment 153036
Great result there. I'd like to see what his donor looks like.
 

pegasus2

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They stoped their Smart Hair Transplant research and took the section out of their website.
Because they already completed it and licensed it to someone else to commercialize. Believe it or not it's not unusual to license out good products to companies that are in a better position to bring them to market. Now they don't have to spend their money to work on it, and can instead concentrate their resources on other ventures.
 

werefckd

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Great result there. I'd like to see what his donor looks like.
It was Dr. Diep who performed it. He documented the case here: https://tinyurl.com/ya6q6ke6

There are no donor area pictures though. But he "only" had 5,202 grafts, so I assume it looks ok, but it's a shame the doctor didn't put pictures of it. I think it's because it was a FUT. He didn't document the crown area either.

PS.: goes to show how Zarev's documentation is good. He always puts pictures of the post op donor area, with perfect lighting and from many different angles. Very methodic and professional.
 
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werefckd

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Because they already completed it and licensed it to someone else to commercialize. Believe it or not it's not unusual to license out good products to companies that are in a better position to bring them to market. Now they don't have to spend their money to work on it, and can instead concentrate their resources on other ventures.
Do you think hair cloning has the difficulty level to be solved such that you can have the luxury to declare your research finished after just some in vitro studies?
 

werefckd

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Look guys, if you think the hair cloning that will finally work will be the one created as a side project of a "organ on a chip" company (Tissuse) that erased such side project from their website, and distributed by an obscure Japanese company (J Hewitt) with no website that has been throwing BS excuses for 1.5 years for not being able to start a 5 people trial, then it's ok, it's your opinion and I respect that. And that's all I have to say about it.
 

H

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unfortunately another false statement. Tissuse is a spin-off from TU Berlin (one of the best universities in Germany) and SHT was also developed there, by Reyk Horland among others. Tissuse itself focuses on organ on a chip processes, but they also have SHT patents from the TU Berlin. The CEO of Tissuse didn't care too much about that, as he never researched it. His research area was in the chip process. That's why it didn't get that much attention.
Weren't they supposed to do trials and then they got cancelled never to be rescheduled as far as we've heard anyway? The problem is that these cloning companies are full of sh*t and hair cloning is very hard. The only other explanation is that theres some type of Murphy's Law tailored to this specific industry whenever it comes to getting a new effective hair loss reversal treatment to commercialization bam the curse takes over and all these poor labs plans are derailed and ya... so they are full of sh*t.
 

pegasus2

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Weren't they supposed to do trials and then they got cancelled never to be rescheduled as far as we've heard anyway? The problem is that these cloning companies are full of sh*t and hair cloning is very hard. The only other explanation is that theres some type of Murphy's Law tailored to this specific industry whenever it comes to getting a new effective hair loss reversal treatment to commercialization bam the curse takes over and all these poor labs plans are derailed and ya... so they are full of sh*t.

Really it's quite common in the industry for effective therapies to be shelved and/or for the companies pursuing them to go bankrupt despite having working treatments. It's not just the hair loss treatments this happens with.
 

jan_miezda

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so what it would be like?
Stemson use much different approach than tsuji. The scaffold itself is a big breakthrough if it can be successfully implanted into scalp with no side effects. The rest can be researched and tweaked. But if the scaffold can be successfully implanted it means that even completely bald people can have hair
 

werefckd

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"In the third generation technology, hair follicles and skin are engineered from induced pluripotent stem cells: this approach benefits patients with congenital alopecia, who lack healthy follicles, or severe baldness, who have almost none. These three generations of hair regeneration technology have paved the way for a new healthcare paradigm in which all types of hair loss are treatable."

Our business model for hair regeneration

Our approach to hair regeneration—autologous transplantation—is to implant follicle germ units originating from stem cells harvested from a patient’s own healthy follicles. For male pattern baldness, we harvest a small number of hair follicles from the patient at a medical facility, and then send them to a contract manufacturer, who isolates, cultures, and amplifies them to generate follicle germ units via the organ germ method. These follicle germs are packaged and shipped back to the medical facility to be transplanted into the patient’s scalp.
We are continuing our R&D in an anticipation of clinical application as the world’s first case of organ regeneration in humans.


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No iPSCs.
 

werefckd

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the question is what density can be obtained, can the scaffold be implanted on the skin where the hair grows, or only on the bald areas?
Not even them knows for sure yet, pre clinical studies will answer a lot of questions regarding that. But I don't see any reason it couldn't be implanted around normal hairs.

I think it will come down to the diameter of the largest part of the scaffold. If it's too large then I can see how it can limit the max density you can get in a single procedure.
 

werefckd

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I wonder if, during trials on people, they will want to make the perfect hairstyle for volunteers, or simply implant a few hair and see how they will behave in a year two
If I were them I would be doing that even before clinical trials. I would be doing right now.
 

werefckd

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so maybe in human trials they will do perfect hair for volunteer
If they conduct robust pre clinical trials, there is a chance they will be able to treat people in the UK (considering they have the logistics there) before the start of clinical (human) trials.
 
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