Apparently Tsuji has started clinical trials

[froggy7]

I wouldn't say it's always a necessity to start longevity experiments on infants only. We've already seen how some aging can be reversed in grown mice by injecting them with stem cells found in the embryo of mice. So who knows, maybe they might use a similar technique.

Regarding the Balding, it seems as if they simply are not concerned with hair. Surely they know they could atleast go for SMP, a hair system, hair transplants, etc but they haven't. Probably because they, like The Rock, Dwayne Johnson, consider themselves better looking without hair.

But once the longevity tech comes along, I doubt it wouldn't be of interest to them to indirectly regrow their hair because one of the methods they also seem to be experimenting with is returning cells to a younger state. By doing such they may be able to turn the cells in the scalp, back in time to a point they weren't sensitive to DHT and hairloss and back to a growth phase.

Who knows, if their successful at re-triggering growth phases in the body, they might even eventually in the distant future be able to create more growth in humans than humans were previously bio-genetically limited to, possibly being able to alter/increase things like height, etc.

mice are not humans, you don't think that a 60-year-old man will go back to his 20-year-old age

 

[cryingariver]

Tsuji, lots of talk but nothing to show. Have no faith in this one, especially with such an amateurish approach and no real money behind the project.

Reminds me of Follica. George Cotsarelis is a piece of sh*t talker and no action, after 15 f*****g years. Hey George, if you're reading this, f*** OFF!!!

 

[cryingariver]

Good luck to Atlos Labs, they will achieve good results but surely the founders can not use it, ..., in order to gain longevity we must start asap, in the infancy. I remember Aubrey de Grey works.

OTOH, both JB&YM are baldies, why don`t repair it?
View attachment 171573

HAHA. Bro, these guys are yesterday's news. Elon Musk is now like 230 billion dollars rich. HE had a hair transplant. Elon is our idol

 

[Micky_007]

mice are not humans, you don't think that a 60-year-old man will go back to his 20-year-old age

Obviously their two different species. But I'm pretty sure the 2nd richest man in the world (Jeff Bezos) and one of the richest tech Billionaires (Yuri Milner) has access to exponentially more information from the best scientists in the world than you. They wouldn't invest in something unless they knew for almost certain that it would be possible.

If you don't know who Yuri Milner is, I suggest you research him.

"Russia's most influential tech investor, Yuri Milner was an early backer of Facebook and Twitter through his venture fund, DST Global.
Milner sold those stakes and later invested in Spotify and Airbnb.
Milner also bet big on Chinese tech companies, including online retailers Alibaba and JD. Com, and mobile phone maker Xiaomi.

A former physicist, Milner is a cofounder of the Breakthrough Prize, which rewards top scientists with lucrative prizes and a glitzy awards ceremony."

" Milner is a Russian-born billionaire who made a fortune on Facebook and Mail.ru and previously started the glitzy black-tie Breakthrough Prizes, $3 million awards given each year to outstanding physicists, biologists, and mathematicians."

Also, Jeff Bezos started his own space company Blue Origin and has gone into space before Elon Musk - sure SpaceX tech is ahead, but at least Bezos speed of implementation can be applauded for beating Musk in that regard.

These 2 multi-billionaires combined money and resources are highly probable more than anyone else to achieve longevity in humans. And they wouldn't have invested in this if they didn't have a strong possibility of success.

They already recruited many of the best in the world researchers, scientists, professors, PHD's:


"Among the scientists said to be joining Altos are Juan Carlos Izpisúa Belmonte, a Spanish biologist at the Salk Institute, in La Jolla, California, who has won notoriety for research mixing human and monkey embryos and who has predicted that human lifespans could be increased by 50 years.

Also joining is Steve Horvath, a UCLA professor and developer of a “biological clock” that can accurately measure human aging. Shinya Yamanaka, who shared a 2012 Nobel Prize for the discovery of reprogramming, will be an unpaid senior scientist and will chair the company’s scientific advisory board.

Yamanaka’s breakthrough discovery was that with the addition of just four proteins, now known as Yamanaka factors, cells can be instructed to revert to a primitive state with the properties of embryonic stem cells. By 2016, Izpisúa Belmonte’s lab had applied these factors to entire living mice, achieving signs of age reversal and leading him to term reprogramming a potential “elixir of life.”

These are not your Average Joe's getting into this. Neither will they have the issue of needing funding like most treatments in the pipeline have difficulty with which are often the reasons for much delays.

Also:

"A number of startups are pursuing reprogramming technology, including Life Biosciences, Turn Biotechnologies, AgeX Therapeutics, and Shift Bioscience in the UK."

“There are hundreds of millions of dollars being raised by investors to invest in reprogramming, specifically aimed at rejuvenating parts or all of the human body,” says David Sinclair, a researcher at Harvard University who last December reported restoring sight to mice using the technique"

I'd say interesting things are ahead lads.

 

[froggy7]

HAHA. Bro, these guys are yesterday's news. Elon Musk is now like 230 billion dollars rich. HE had a hair transplant. Elon is our idol

only a loser gets married with so much money

 

[froggy7]

Obviously their two different species. But I'm pretty sure the 2nd richest man in the world (Jeff Bezos) and one of the richest tech Billionaires (Yuri Milner) has access to exponentially more information from the best scientists in the world than you. They wouldn't invest in something unless they knew for almost certain that it would be possible.

If you don't know who Yuri Milner is, I suggest you research him.

"Russia's most influential tech investor, Yuri Milner was an early backer of Facebook and Twitter through his venture fund, DST Global.
Milner sold those stakes and later invested in Spotify and Airbnb.
Milner also bet big on Chinese tech companies, including online retailers Alibaba and JD. Com, and mobile phone maker Xiaomi.

A former physicist, Milner is a cofounder of the Breakthrough Prize, which rewards top scientists with lucrative prizes and a glitzy awards ceremony."

" Milner is a Russian-born billionaire who made a fortune on Facebook and Mail.ru and previously started the glitzy black-tie Breakthrough Prizes, $3 million awards given each year to outstanding physicists, biologists, and mathematicians."

Also, Jeff Bezos started his own space company Blue Origin and has gone into space before Elon Musk - sure SpaceX tech is ahead, but at least Bezos speed of implementation can be applauded for beating Musk in that regard.

These 2 multi-billionaires combined money and resources are highly probable more than anyone else to achieve longevity in humans. And they wouldn't have invested in this if they didn't have a strong possibility of success.

They already recruited many of the best in the world researchers, scientists, professors, PHD's:


"Among the scientists said to be joining Altos are Juan Carlos Izpisúa Belmonte, a Spanish biologist at the Salk Institute, in La Jolla, California, who has won notoriety for research mixing human and monkey embryos and who has predicted that human lifespans could be increased by 50 years.

Also joining is Steve Horvath, a UCLA professor and developer of a “biological clock” that can accurately measure human aging. Shinya Yamanaka, who shared a 2012 Nobel Prize for the discovery of reprogramming, will be an unpaid senior scientist and will chair the company’s scientific advisory board.

Yamanaka’s breakthrough discovery was that with the addition of just four proteins, now known as Yamanaka factors, cells can be instructed to revert to a primitive state with the properties of embryonic stem cells. By 2016, Izpisúa Belmonte’s lab had applied these factors to entire living mice, achieving signs of age reversal and leading him to term reprogramming a potential “elixir of life.”

These are not your Average Joe's getting into this. Neither will they have the issue of needing funding like most treatments in the pipeline have difficulty with which are often the reasons for much delays.

Also:

"A number of startups are pursuing reprogramming technology, including Life Biosciences, Turn Biotechnologies, AgeX Therapeutics, and Shift Bioscience in the UK."

“There are hundreds of millions of dollars being raised by investors to invest in reprogramming, specifically aimed at rejuvenating parts or all of the human body,” says David Sinclair, a researcher at Harvard University who last December reported restoring sight to mice using the technique"

I'd say interesting things are ahead lads.

the new trend will be - immortality is just around the corner, 5 years away only

 

[Micky_007]

the new trend will be - immortality is just around the corner, 5 years away only

No. Literally no one is talking about immortality. There's a major difference between immortality and longevity. Also, no one has given any timelines but even if they did, everything that was ever invented started off with talks of "in the future" or "in a few years time" which is perfectly fine. It's quite amazing to finally be able to say in the foreseeable future we can expect stuff like this.

Even with hairloss, we've had a lot of "in the next 5 years" but look at the tech and methods of approach that have progressively come out since then, it's at a higher level and it a does take time.

 

[froggy7]

No. Literally no one is talking about immortality. There's a major difference between immortality and longevity. Also, no one has given any timelines but even if they did, everything that was ever invented started off with talks of "in the future" or "in a few years time" which is perfectly fine. It's quite amazing to finally be able to say in the foreseeable future we can expect stuff like this.

Even with hairloss, we've had a lot of "in the next 5 years" but look at the tech and methods of approach that have progressively come out since then, it's at a higher level and it a does take time.

it's true what you go, that's why older people over 30 will not get these treatments, there is cryonics

 

[Micky_007]

it's true what you go, that's why older people over 30 will not get these treatments, there is cryonics

As I said before, as long as people are younger than Jeff Bezos and healthy, they also have a chance. Provided they have the money when it does become available. There's no way Bezos and Milner would invest in this if it can't be achieved within their non-extended lifetime.

Best believe they will test their treatment on many people before they decide its safe for them to try it on themselves.

 

[froggy7]

As I said before, as long as people are younger than Jeff Bezos and healthy, they also have a chance. Provided they have the money when it does become available. There's no way Bezos and Milner would invest in this if it can't be achieved within their non-extended lifetime.

Best believe they will test their treatment on many people before they decide its safe for them to try it on themselves.

this treatment will not turn 60-year-old Bezos into 20-year-old Bezos

 

[Micky_007]

this treatment will not turn 60-year-old Bezos into 20-year-old Bezos

You can't say with such certainty that it is impossible because 1 treatment could be improved upon over and over as time goes by as they get better and better technology and knowledge. They may start with something that can extend life by 5 or 10 years then 20, 30, etc.

 

[froggy7]

You can't say with such certainty that it is impossible because 1 treatment could be improved upon over and over as time goes by as they get better and better technology and knowledge. They may start with something that can extend life by 5 or 10 years then 20, 30, etc.

I agree, but this treatment will only rejuvenate us internally or externally too?

 

[LouisSarkozy]

I agree, but this treatment will only rejuvenate us internally or externally too?

this . will it reshape facal tissue to what they used to be? obviously not

 

[froggy7]

this . will it reshape facal tissue to what they used to be? obviously not

then what kind of rejuvenation is it?

 

[Chads don't bald]

then what kind of rejuvenation is it?

Look up epigenetic reprogramming: https://www.nature.com/articles/s41586-020-2975-4

Partial Reprogramming Rejuvenates Human Cells by 30 Years | Lifespan.io

Researchers from the Reik lab at the Babraham Institute have used the four Yamanaka reprogramming factors (OSKM) in order to epigenetically […]

www.lifespan.io

Success in Reprogramming a Supercentenarian’s Cells | Lifespan.io

Researchers from AgeX Therapeutics and other organizations have proved the feasibility of reprogramming banked cells derived from a supercentenarian. Their discovery portends exciting new possibilities for aging research. What is cellular reprogramming? Cellular reprogramming is the process of...

www.lifespan.io

There is no upper age limit

Basically no matter how old you are, they can reprogram you to be young again. That means your skin will look young again, your heart will be young again, your muscles will be young again, your metabolism will be young again, your brain will be young again (you get back your fluid intelligence) etc.

 

[surfer9]

does that mean u won't die from 'old age'.

Surely people would get bored of life if you ruled out dying from old age. Stay looking and feeling age 25 until you die.....of which death will likely be caused by an accident.

Prob good if you had good looks and you are rich. But if you go back to being an ugly 25 year old with no money you might as well avoid this reprogramming. You will never get a pension, you will have to work forever, or until the fork lift truck hits you at the warehouse you stack shelves at.

 

[trialAcc]

Look up epigenetic reprogramming: https://www.nature.com/articles/s41586-020-2975-4

Partial Reprogramming Rejuvenates Human Cells by 30 Years | Lifespan.io

Researchers from the Reik lab at the Babraham Institute have used the four Yamanaka reprogramming factors (OSKM) in order to epigenetically […]

www.lifespan.io

Success in Reprogramming a Supercentenarian’s Cells | Lifespan.io

Researchers from AgeX Therapeutics and other organizations have proved the feasibility of reprogramming banked cells derived from a supercentenarian. Their discovery portends exciting new possibilities for aging research. What is cellular reprogramming? Cellular reprogramming is the process of...

www.lifespan.io

There is no upper age limit

Basically no matter how old you are, they can reprogram you to be young again. That means your skin will look young again, your heart will be young again, your muscles will be young again, your metabolism will be young again, your brain will be young again (you get back your fluid intelligence) etc.

This is false afaik. You are correct that you could look 20 for the duration of your life by resetting cell health (and we're getting closer to cracking this), but cells have mechanisms that do have an upper cap on lifespan (i believe it has to do with telomeres) that expire after about an estimated 130-150. Once that is solved and can be augmented, then you're looking at no real bound.

 

[fashy]

I love all this talk about hair related issues on hairlosstalk.com threads and how it doesn't get constantly derailed about the coping fantasies of eternal life by the mentally ill demographic on the site.

 

[Chads don't bald]

This is false afaik. You are correct that you could look 20 for the duration of your life by resetting cell health (and we're getting closer to cracking this), but cells have mechanisms that do have an upper cap on lifespan (i believe it has to do with telomeres) that expire after about an estimated 130-150. Once that is solved and can be augmented, then you're looking at no real bound.

Nope if you read the 3rd link I posted, it mentions that telomeres were also reset.

"One substantial difference did arise: in iPSCs derived from all three donors, telomere length, which declines with age (or as a result of progeria) was completely reset to nearly embryonic levels." Now the supercentenarian cells didn't rejuvenate their telomeres as well as the other groups, but that isn't really a big issue as we can already lengthen telomeres if we wish to. I believe you are speaking of the Hayflick limit which is also irrelevant with the kind of biotech we have now.

I love all this talk about hair related issues on hairlosstalk.com threads and how it doesn't get constantly derailed about the coping fantasies of eternal life by the mentally ill demographic on the site.

This is actually very relevant to hair loss. If you can epigenetically reprogram your hair follicles you can prevent them from becoming progressively more sensitive to DHT with age. It could also possibly allow you to grow hair on a shiny dome, who knows.

Turn Bio is already working on this angle by reprogramming the epigenome.

Turn Biotechnologies: mRNA Hair Growth Therapy - Follicle Thought

Today, I am pleased to introduce yet another company entering the hair growth treatment industry, Turn Biotechnologies. The company is creating therapies which restore human cells to a more youthful state and has a program targeting skin and hair. Turn Biotechnologies is one of the latest...

www.folliclethought.com

Educate yourself before commenting!

 

[trialAcc]

I love all this talk about hair related issues on hairlosstalk.com threads and how it doesn't get constantly derailed about the coping fantasies of eternal life by the mentally ill demographic on the site.

Maybe you're just too dumb to realize that if you can cure cell decay (an area with billions of dollars and main stream attention flowing into it yearly), you also have cured hairloss long before (an area that the global medical/regular community largely ignores).

But sure, we're just mentally ill, along with some of the most brilliant scientists, businessmen and philanthropists in the world who are turning their attention to cell rejuvenation.