Bayer Prolactin Receptor Antibody For Male And Female Pattern Hair Loss

[pegasus2]

Thank you For explanation.
But where was mentioned that Australian Agency didnt give permission For phase 2? In the News Release of Hope Medicine they Said that they will Launch Phase II in Australia :

„Its Phase II clinical trial for the treatment of androgenetic alopecia is an international multi-center, randomized, double-blind, placebo-controlled study, which is planned to be carried out in the United States, Australia and other countries.“

Australia clearly wanted a phase I in men. No other reason for them to do this. It could also be a combined phase 1/2, and there may be a separate phase 2 coming now in the US and Europe. At least we know why it was delayed, and they aren't waiting for regulatory decisions anymore. They can now move forward with whatever they plan to do. If they're running a ph2 concurrently in the US we'll know soon.

 

[Hope111]

Do you think that over a few years the price of this possible solution would be affordable? (20/30k)

 

[pegasus2]

Do you think that over a few years the price of this possible solution would be affordable? (20/30k)

Yes. Should be comparable to a hair transplant in the US, so around that price for 6 months.

 

[HMI 115 IS THE CURE dude]

Do you think that Bayer and FUE can be some sort of a cure?

i dont know if FUE will even be required, if the results translate as well as they did with monkeys to human (which im sure everyone remains skeptical of, for good reason) .. why you think you will need FUE too?

 

[kuba197]

i dont know if FUE will even be required, if the results translate as well as they did with monkeys to human (which im sure everyone remains skeptical of, for good reason) .. why you think you will need FUE too?

To restore frontal areas

 

[HMI 115 IS THE CURE dude]

To restore frontal areas

thats true but in the animal studies i was impressed how there was consistent growth even in the front of scalp

 

[Joxy]

thats true but in the animal studies i was impressed how there was consistent growth even in the front of scalp

Frontal areas are most important in general picture of your hair style. If they don’t show impressive growth in frontal areas, so there will be no point in hype of this product.

 

[coolio]

Frontal areas can be done pretty well with transplants - if you have enough top/crown coverage to support it.

Minoxidil & Finasteride were both marketed as "only tested on the crown".

 

[whatevr]

Do you think that over a few years the price of this possible solution would be affordable? (20/30k)

f*****g hell. Over for poorcels.

20-30k should be the initial price if anything, after a few years I would expect it to drop to 2-3k otherwise it's ridiculous. For 20-30k I would expect very little short of full regrowth.

 

[Numerous_Bet_3027]

People from Australia can be cured for free and apply here:

Dermatology Clinical Trials | Sinclair Dermatology

Spread the word, would be extremely interesting if we got someone we know into the trials.

 

[RolfLeeBuckler]

People from Australia can be cured for free and apply here:

Dermatology Clinical Trials | Sinclair Dermatology

Spread the word, would be extremely interesting if we got someone we know into the trials.

Unfortunately only For Victorian residents

 

[Hope111]

maldito infierno. Terminado para los pobres.

20-30k debería ser el precio inicial en todo caso, después de unos años esperaría que cayera a 2-3k , de lo contrario es ridículo. Para 20-30k esperaría muy poco menos que un rebrote completo.

But would this be a unique treatment or would it have to be repeated from time to time?

 

[trialAcc]

f*****g hell. Over for poorcels.

20-30k should be the initial price if anything, after a few years I would expect it to drop to 2-3k otherwise it's ridiculous. For 20-30k I would expect very little short of full regrowth.

It's a mAb dude, the average price is almost 100k for current approved treatment courses. This one might be cheaper but it's never going to be 2-3k. The covid anti-viral mAb that countries have been using is 2k a dose at bulk cost. Apply that to this, 24 doses for a years treatment, and you'd have $48,000.

 

[Zon Ama]

Before talking about the costs, it should be working on humans. If the treatment works like it does on monkeys, I would be very relieved.

Is anyone here from Australia and thinking about getting in those trials?

 

[pegasus2]

People from Australia can be cured for free and apply here:

Dermatology Clinical Trials | Sinclair Dermatology

Spread the word, would be extremely interesting if we got someone we know into the trials.

Also the sooner they get 20 people enrolled the sooner we will get the trial results

 

[LoWS]

No point in talking about the costs now, i know mAB is costly af based on other conditions, but hairloss is a mass market issue, price should be affordable if not in the US then in other countries. Drugs in USA costs a lot more in general. But before all this i would be relieved if this drug is safe efficacious, having a costly treatment >> no treatment.

 

[trialAcc]

No point in talking about the costs now, i know mAB is costly af based on other conditions, but hairloss is a mass market issue, price should be affordable if not in the US then in other countries. Drugs in USA costs a lot more in general. But before all this i would be relieved if this drug is safe efficacious, having a costly treatment >> no treatment.

Yeah, the price is irrelevant at this point. We should just be hoping that this actually is a step towards a legitimate treatment or even semi-cure if it corrects the root cause of the problem. After that's been validated, we can worry about how much it will cost us.

 

[RolfLeeBuckler]

Why does Hope Medicine start clinical Trial of HMI-115 in Australia of they have to do a Phase I there?

Why doesn‘t Hope Medcine Start clinical trials in US and Europe of they could start already Phase II and bring the Treatment much earlier to Market?

 

[Dimitri001]

This applies to literally any drug being developed... Don't worry, be happy

It doesn't, there's plenty of drugs that were available while being researched and even if it did it wouldn't invalidate the point.

 

[Dimitri001]

Also the sooner they get 20 people enrolled the sooner we will get the trial results

Yeah, we should spread the word on Tressles and whatever other forums.

No point in talking about the costs now, i know mAB is costly af based on other conditions, but hairloss is a mass market issue, price should be affordable if not in the US then in other countries. Drugs in USA costs a lot more in general. But before all this i would be relieved if this drug is safe efficacious, having a costly treatment >> no treatment.

Well, the fact that there is a mass market for it doesn't mean they'll sell at a mass market price. Perhaps it can't even be produced at a mass market cost. If the price for existing antibody treatments is 100k, like trialAcc says, it could be comparable and if the price is 100k, for a lot of people, myself included, it may as well be 100 billion, that's completely out of my price range. I could sell everything I own and still be short.

So I disagree with the idea that we shouldn't worry about the price until we have the results, because what good are spectacular results if you can't ever have them. We can be sitting here with baited breath until next summer and then find out all the subjects regrew hair and then you gotta come up with 100k - so what good did it do us at that point that we know HMI is the cure? If this thing is gonna work for us, we either need to know it will be affordable or find some other drug to target the PRL angle with, because, again, if this thing is a cure, but costs 100k, for me, that's no different than there being no cure, because my finances simply cannot stretch that far, not even close, and I'm sure the same is true for a lot of people.