Cassiopeia Release Full Year Results To 2018 Including Update On Breezula

[Badbald]

2022. When we’re all bald.

Well luckily we can still get hold of it, if its something you cant wait for you should invest some time and money into getting it now.

I know its not perfect with the method of delivery for absorption and purity but its meant to be easily absorbed due to its molecular weight I think we should still be able to get the basic compound to do its job

 

[Vinc2097]

Well luckily we can still get hold of it, if its something you cant wait for you should invest some time and money into getting it now.

I know its not perfect with the method of delivery for absorption and purity but its meant to be easily absorbed due to its molecular weight I think we should still be able to get the basic compound to do its job

this is the best scenario for some, but not for canadiens like me, customs aint letting this sh*t thru borders

 

[Phatalis]

this is the best scenario for some, but not for canadiens like me, customs aint letting this sh*t thru borders

I don't think the U.S. will either..my shits been in customs since February 6th

 

[Meeee199]

2022. When we’re all bald.

 

[Badbald]

Yep CB seems to be fairly easy for labs to compound so wheres theres a will theres a way in terms of getting hold of it no matter where you are

 

[Phatalis]

you might have a better chance if you send it to britain first and then reroute it to the US. I think customs for parcels from europe is less rigorous than from china due to obvious reasons(fentanyl etc) so I assume they would allocate most of their resources to traffic from asia. I think that'd be worth a shot if it really doesn't work out and with the millions of packages being sent from europe every day you'd have to be quite unlucky to get busted. and even if you get busted once in a while, most would offer to send another one for free from what I have read

Yeah we'll see. I think wuhan will send another for free.

Also - it was terouted through germany

 

[kungfukenny]

Is CB an anti androgen?

 

[Tom4362]

Does anyone know how to get in contact with @bryan2003? He didn't answer my email

 

[TK421]

So CB binds to androgen receptors so dht can't bind to them, right? How is this going to be any more effective than Eucapil (fluridil/topilutamide)?

 

[alibaba92]

So CB binds to androgen receptors so dht can't bind to them, right? How is this going to be any more effective than Eucapil (fluridil/topilutamide)?

From what I read,

CB is steroidal AA (https://en.wikipedia.org/wiki/Steroidal_antiandrogen)

RU, Fluridil, etc. are non-steroidal AA (https://en.wikipedia.org/wiki/Nonsteroidal_antiandrogen)

In short, seems like non-steroidal AA is preferred cause they are the full antagonist of ARs, and have no capacity to activate ARs, unlike steroidal AA, which can activate even more ARs, and may not be strong enough to compete with DHT for a same receptor. No wonder, RU was said to be much more effective and users reported a lot of regrowth.

Seems like CB may have a possibility activate even more ARs, which lead to ... more hair loss ?

Dont quote me on the above, I am happy to be educated as well.

 

[ScaredOfBalding]

From what I read,

CB is steroidal AA (https://en.wikipedia.org/wiki/Steroidal_antiandrogen)

RU, Fluridil, etc. are non-steroidal AA (https://en.wikipedia.org/wiki/Nonsteroidal_antiandrogen)

In short, seems like non-steroidal AA is preferred cause they are the full antagonist of ARs, and have no capacity to activate ARs, unlike steroidal AA, which can activate even more ARs, and may not be strong enough to compete with DHT for a same receptor. No wonder, RU was said to be much more effective and users reported a lot of regrowth.

Seems like CB may have a possibility activate even more ARs, which lead to ... more hair loss ?

Dont quote me on the above, I am happy to be educated as well.

No that's not right. CB will work just fine, it might be slightly less effective than RU, but not huge. U can't really expect full regrowth from any anti-androgen anyways. CB has shown an average of 20 hairs/cm2 in 6 months which is very good. I expect it to go to 25-30 hairs/cm2 at 12 months which is basically 15% of ur original density u get back for caucasians. The decline in hair count will probably be very similar to finasterde but might be even slower so i expect that most people will be able to maintain on 7.5% 2x/day for 10-15 years or more. And even then the decline below baseline will be slow. In my opinion this is far more interesting at the moment than any other treatment coming out.

 

[alibaba92]

No that's not right. CB will work just fine, it might be slightly less effective than RU, but not huge. U can't really expect full regrowth from any anti-androgen anyways. CB has shown an average of 20 hairs/cm2 in 6 months which is very good. I expect it to go to 25-30 hairs/cm2 at 12 months which is basically 15% of ur original density u get back for caucasians. The decline in hair count will probably be very similar to finasterde but might be even slower so i expect that most people will be able to maintain on 7.5% 2x/day for 10-15 years or more. And even then the decline below baseline will be slow. In my opinion this is far more interesting at the moment than any other treatment coming out.

Relax, I am just pointing out a science aspect since the guy asked what the difference was between the 2 AAs. As I said, I am happy to be educated. Wiki may be not right as well, but it serves as a reference

 

[alibaba92]

and why does winlevi improve acne significantly and not leave behind an even worse case of it? something in your theory is definitely not right but I can't point it out because I am not a biologist-maybe someone else can

You seemed triggered and over-excited whenever someone attack CB ? None of what I said is my theory. I just point out a science aspect of the 2 AAs from Wiki, which may be wrong. As I said, I am open and happy to be educated. Most of the people here, including me, have very limited knowledge in the medicine field. Hopefully some one with more profound knowledge can chime in.

And for whatever fact, there was no member reported regrowth from using CB, but, there are few success with regrowth from using RU, in the past.

 

[alibaba92]

this sounds like borderline bro science. you are basically saying steroidal AAs do not work which doesn't make any sense otherwise why would they be used for prostate cancer? to give people even more cancer? why does CB work in the studies? why does CB give dutasteride like results when injected under the skin? do you have this "Knowledge" form the badltruthtalk post? why is CB shown to be 3 times more potent as an AA than flutamide in the lab?

Can you pause for a while and read wiki and my post ? I am just saying, non-steroidal AAs should be more favorable over steroidal AAs (reason, read wiki). I never said CB did not work.

 

[ScaredOfBalding]

Relax, I am just pointing out a science aspect since the guy asked what the difference was between the 2 AAs. As I said, I am happy to be educated. Wiki may be not right as well, but it serves as a reference

The only difference is the chemical structure, hence steroidal and non-steroidal i don't know what the f*** u were talking about but it was incorrect so i pointed it out.

 

[alibaba92]

The only difference is the chemical structure, hence steroidal and non-steroidal i don't know what the f*** u were talking about but it was incorrect so i pointed it out.

Ok then. Appreciate that.

 

[alibaba92]

No that's not right. CB will work just fine, it might be slightly less effective than RU, but not huge. U can't really expect full regrowth from any anti-androgen anyways. CB has shown an average of 20 hairs/cm2 in 6 months which is very good. I expect it to go to 25-30 hairs/cm2 at 12 months which is basically 15% of ur original density u get back for caucasians. The decline in hair count will probably be very similar to finasterde but might be even slower so i expect that most people will be able to maintain on 7.5% 2x/day for 10-15 years or more. And even then the decline below baseline will be slow. In my opinion this is far more interesting at the moment than any other treatment coming out.

Hope you are right.

 

[ScaredOfBalding]

Ok then. Appreciate that.

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Yes this is interesting indeed. I did some research on it :
Although they are described as antiandrogens and indeed show only such effects generally, most or all steroidal AR antagonists are actually not silent antagonists of the AR but rather are weak partial agonists and are able to activate the receptor in the absence of more potent AR agonists like testosterone and DHT.
So in short: Yes CB is a SAA and therefor might be able to to weakly activate the AR receptor but only in the absence of DHT and Testosterone. A NSAA might indeed be slightly more effective in treating male pattern baldness but the difference will be minimal. This effectiveness will only be noticed when u remove DHT and T from the scalp aswell.

 

[Baldy12345]

It was mentioned that CB is 30% more effective than finastride is that right?

 

[Baldy12345]

If that’s true, then that’s incredible, since CB has no sides.