Cassiopeia Release Full Year Results To 2018 Including Update On Breezula

Long John Silver

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wow this is the most moronic answer possible. how about you test your sh*t then? then maybe you won't get scammed. people have tested the CB for 60 for years now and never had any issues with it. just because some other dude charges 10$ more doesn't make it safer and more pure. these companies still have a massive profit margin, we are talking about a f*****g gram of a chemical that is not actually THAT hard to make. have fun getting stuff just as impure and fake but paying 20$ more per gram. also your comparison of mac with 1 gram of CB.. no f*****g comment.. apple could still probably profit in that case though lol.

>Then there is the fact that no one has gotten any real results anywhere except for the private forum that actually produced this and many other things including the vehicles.

and with paying more your results will improve? people haven't had results because they use bad dosages and only use it once a day almost universally. if you get tested and it's pure then that's it. if you don't get it tested then you are an actual idiot
Bro I've been polite with you and just pointing out issues in general here for everyone. Don't get twisted with me. I've tested my stuff but no you go jump ahead to your own assumption. Gram of a chemical that you know nothing let alone cost of producing it. You keep talking about Macs and I said Merc. I think you've already had enough powder.

Sure sure and you don't think they've caught on to testing and camouflaging. The testing I did was very expensive and with double PhD else it would pass any rudimentary test your measly $60 and ''' uni bud' illegally would do.

I would gladly pay more to support a place that actually makes things happen and always has been and they have the results to prove it and in turn I get exactly what I want every single time without issue.
 

Long John Silver

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I don't believe you landed in the hospital if your CB was legit tbh. what was the issue? they can't fake a 99% purity, no f*****g way. and they don't have to, why would they after all, CB is not GOLD, it's not that expensive in production especially when you are in china. and 60$ is already enough pay to support a decent place. 85$ is a massive rip off
Bro you are free to believe what you want. I will write it up soon. I didn't even pay $60. You get what you pay for in life. You seem to be poor so need to save $20 taking a greater risk and possibly death but that's your choice. You are from qualified to know production cost and guessing out blue sky. I would rather not get fucked or scammed anymore and want the best highest quality without question and if that supports the place to bring us even more chemicals awesome.
 

Long John Silver

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you are so vague in your responses that it definitely makes me believe that you are making sh*t up. your buddy from testing said "they got better, we found a lot of fake stuff" so why didn't they identify yours as fake? knowing about all those tricks and you having invested so much money into testing? also if they camouflage it then probably not with something that is actually dangerous, that seems like really bad strategy to keep your customers. you would want something that has no effect at all and doesn't harm people, not something that fucks you up. you also haven't posted any proof yet and guys have been using wuhan for years now and nobody has had a problem. so I think you will understand if people are sceptic
Bro you run your own angles and make things up as you go along and imagining things how it suits you. Once I post soon you'll see how tricky and devious it is but you go ahead and do what you want. Clearly you need your $25 and not your health or well being.
 

Ollie

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Wuhan is selling CB at $38 a gram. I’m waiting on hearing back from other labs to do a price comparison.
 

Phatalis

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I keep hearing stuff about a "private forum".

Just curious, why the f*** is it so private? Can other people join? Is it a secret club? Wtf?
 

Phatalis

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I don’t know, @el_duterino has been using neogenic as a vehicle for ages. Has worked well. I have used it for RU. Worked well for that. Hopefully it will work for this as well.

I wanted to trust that stuff but I've seen the el duterino guy write completely contradicting stuff within a week of certain posts.

Not trying to sound like a dick I'm open to be proven wrong and nothing against the dude

Neogenic is expensive as f*** also and from the patent CB doesn't work as well in an aqueous vehicle, which neogenic is.

But hey man, if I'm proven wrong, it does make it easier to just toss the sh*t in neogenic and go
 
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Test subject X

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I wanted to trust that stuff but I've seen the el duterino guy write completely contradicting stuff within a week of certain posts.

Not trying to sound like a dick I'm open to be proven wrong and nothing against the dudeki

Neogenic is expensive as f*** also and from the patent CB doesn't work as well in an aqueous vehicle, which neogenic is.

But hey man, if I'm proven wrong, it does make it easier to just toss the sh*t in neogenic and go

Not defending el duterino but I purchased Garnier Fructis Stemoxydine Neogenic - 2 pack @ 84ML for $30 on ebay. Thats cheap.

But I agree. Many unkowns and questions. So far i found three members on CB that actively post.. Hilbert, Swingbeam and el duterino and there doses and vehicles vary. I'll try with the simplest veh and build from there .

f***... what has life led me to. Im buying questionable chemicals from china to put it in my hair. LMAO! Im either very smart and ahead of the curve... or very very stupid.
 

Phatalis

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Not defending el duterino but I purchased Garnier Fructis Stemoxydine Neogenic - 2 pack @ 84ML for $30 on ebay. Thats cheap.

But I agree. Many unkowns and questions. So far i found three members on CB that actively post.. Hilbert, Swingbeam and el duterino and there doses and vehicles vary. I'll try with the simplest veh and build from there .

f***... what has life led me to. Im buying questionable chemicals from china to put it in my hair. LMAO! Im either very smart and ahead of the curve... or very very stupid.

Doing what you gotta do man. Ahead of the curve and daring. It's not stupid, there isn't other options. It's risky? Yeah for sure.

Also I have no issues with el dute haha. Just pointing stuff out.
 

Phatalis

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I have a bad feeling. That for U.S. guys this is all moot anyhow. My shits been in customs since last Wednesday.
 

Phatalis

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I thought the vehicle they used is in the paper/patent? I don't think it's too much about the vehicle, I think the most crucial point for why people haven't had decent success is the once a day thing

***This is what they used***

"The formulation described in Example 4 was studied in a clinical trial to evaluate its pharmacokinetic profile, safety, and tolerability. According to the study protocol, 1 ml of the formulation (corresponding to 50 mg of cortexolone-17α-propionate) was applied once a day on study day 1 and then twice daily thereafter on study days 2-28 to the areas of the scalp suffering from alopecia."

  • Example 4: Anhydrous 5% w/w Solution
  • [0152]
    A 5 weight percent (w/w) solution of cortexolone-17α-propionate having the components shown in Table 4, below, was prepared by solubilizing the therapeutic agent in the mixture of solvents followed by the addition of the antioxidant (ascorbyl palmitate) and the emulsifier (polysorbate 80). Table 4
    Component
    Amount (g/100 g) Amount (Kg/ 15 Kg batch)
    Cortexolone-17α-propionate 5.00 0.75
    Diethylene glycol monoethyl ether 31.50 4.725
    Alcohol (Ethanol) 31.50 4.725
    Ascorbyl palmitate 0.50 0.075
    Polysorbate 80 0.10 0.015
    Propylene glycol 31.40 g 4.710

I don't think that's testing the dosage or how effective CB is, just as stated... it's simply testing the safety profile basically. So it may NOT be the BEST vehicle. But it is what's listed.

As for what they were using for phase II, could be the same, could be different.
 
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Phatalis

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  • Example 5: Aqueous 5% w/w Solution
  • [0154]
    A formulation of cortexolone-17α-propionate having the components shown in Table 6, below, was prepared by solubilizing the therapeutic agent in the mixture of solvents followed by the addition of the antioxidant and the emulsifier. Table 6 : aqueous solution 5% w/w
    Component
    Amount (g/100 g) Amount (Kg/ 15 Kg batch)
    Cortexolone-17α-propionate 5.00 0.750
    Transcutol 46.10 6.915
    Purified water 28.30 4.245
    Ethanol 20.00 3.00
    Polysorbate 80 0.50 0.075
    Alpha tocopherols (vitamin E) 0.10 0.015
    Citric acid, monohydrate Q.s. to bring the pH to 4.0-4.5 Q.s. to bring the pH to 4.0-4.5
  • [0155]
    The stability of this formulation at 40 °C/75% RH is shown in Table 7.Table 7
    Time point Cortexolone-17α-propionate (% W/W) Cortexolone 21-propionate % Total impurities %
    0 5.127 0.08 0.14
    1 month 5.064 1.19 1.38
    3 months 4.962 3.79 4.21
    6 months 4.546 7.66 8.41
  • [0156]
    Based on the impurity profile, the formulation prepared in Example 4 is more stable than the aqueous formulation of Example 5.
 

Ollie

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  • Example 5: Aqueous 5% w/w Solution
  • [0154]
    A formulation of cortexolone-17α-propionate having the components shown in Table 6, below, was prepared by solubilizing the therapeutic agent in the mixture of solvents followed by the addition of the antioxidant and the emulsifier. Table 6 : aqueous solution 5% w/w
    Component
    Amount (g/100 g) Amount (Kg/ 15 Kg batch)
    Cortexolone-17α-propionate 5.00 0.750
    Transcutol 46.10 6.915
    Purified water 28.30 4.245
    Ethanol 20.00 3.00
    Polysorbate 80 0.50 0.075
    Alpha tocopherols (vitamin E) 0.10 0.015
    Citric acid, monohydrate Q.s. to bring the pH to 4.0-4.5 Q.s. to bring the pH to 4.0-4.5
  • [0155]
    The stability of this formulation at 40 °C/75% RH is shown in Table 7.Table 7
    Time point Cortexolone-17α-propionate (% W/W) Cortexolone 21-propionate % Total impurities %
    0 5.127 0.08 0.14
    1 month 5.064 1.19 1.38
    3 months 4.962 3.79 4.21
    6 months 4.546 7.66 8.41
  • [0156]
    Based on the impurity profile, the formulation prepared in Example 4 is more stable than the aqueous formulation of Example 5.


For whatever reason in the first trials they didn’t use water. If water could however be used then I would make liposomes so our solution would be much more cost effective.
 

Phatalis

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thats just one week for now. I think it will probably be fine

Man I fuckin hope so. I just want this sh*t to work out so I don't have to stress about it.

I already ordered all the sh*t. And if it works I'd help anyone on here do what I did. Like a guide. Like hellouser or some sh*t
oh ok. oh f***, I thought we have figured it all out and just need to get the CB and we are ready to go. this sh*t always comes with so many hooks, impurity, customs, vehicle, actual efficiency.. I read a post recently on bald truth talk about CB vehicle, that was written 5 years ago-absolutely no progress it seems since then. everything is so depressing

I mean I feel like it is mostly figured out man. The example 4 vehicle was used, which means they were confident enough in it working so they could analyze safety profile etc... so I'm sure it'll suffice... and Desmond is apparently working on a better vehicle in theory... and he's a smart cookie. I trust him.

The biggest hurdles we have right now are (cost / getting through customs / purity and purity testing)
 

Phatalis

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For whatever reason in the first trials they didn’t use water. If water could however be used then I would make liposomes so our solution would be much more cost effective.

Yeah I posted that Example 5 to show they DID NOT use it because it was an aqueous solution and didn't play as well with CB
 

Ollie

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oh ok. oh f***, I thought we have figured it all out and just need to get the CB and we are ready to go. this sh*t always comes with so many hooks, impurity, customs, vehicle, actual efficiency.. I read a post recently on bald truth talk about CB vehicle, that was written 5 years ago-absolutely no progress it seems since then. everything is so depressing

Dude as @Phatalis has said its basically figured out. The vehicle options are either Transcutol: pg: Eth or the special vehicle from Fagron. I'm still waiting on a couple of labs to get back but Wuhan has said $38 a gram. We might even be able to get them to sign a purity consensus so if the tests came back < 99% we could claim the money back.
 
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