Connecting The Dots And Finding The Mechanisms

[Hate da Bt]

All these years watching these forums. It makes me shake my head how we eat our own. We are all suffering from the same thing. And then every once in a while, a real special case like your own comes along...... you haven’t contributed one constructive thing to any forum. Ever. You sleep on your dislike buttons and insult everyone without ever contributing to anything. Moving on. I’ll take your dislike as an upvote. Thank you.

That's the point, loser, I don't consider balding a suffering.
It's just that I want to be the best version of myself and being bald is definitely not the best option.
I can live with baldness, though.
I may no longer be an 8, but I can live with it.

Give me one point of each that I got wrong

You explain me how mechanical stress leads to DHT-driven miniaturization, and also what kind of fibrosis crops up in a balding scalp.

Don't plan on buying any Brotzu anytime soon, chief

I don't. But you made me laugh.

 

[Arrade]

That's the point, loser, I don't consider balding a suffering.
It's just that I want to be the best version of myself and being bald is definitely not the best option.
I can live with baldness, though.
I may no longer be an 8, but I can live with it.



You explain me how mechanical stress leads to DHT-driven miniaturization, and also what kind of fibrosis crops up in a balding scalp.


I don't. But you made me laugh.

I don't believe in the mechanical stress theory. I think it's build up of calcium or fibrosis that leads the scalp muscles to being stiff, not any action or inaction of the muscles themselves.
Then again something about myofascial release, like using a lacrosse ball to unstiffen your back muscles is actually breaking up fibrosis

 

[couldntthinkofaname]

Hahaha
I'd still shag him, though...
I don't like my men pretty.

he has a better hairline than me

feels bad

feels really bad

 

[Hate da Bt]

I don't believe in the mechanical stress theory. I think it's build up of calcium or fibrosis that leads the scalp muscles to being stiff, not any action or inaction of the muscles themselves.
Then again something about myofascial release, like using a lacrosse ball to unstiffen your back muscles is actually breaking up fibrosis

What???
Man, I refuse to engage in this any further.
Do you!
I'm out!

 

[HairSuit]

What???
Man, I refuse to engage in this any further.
Do you!
I'm out!

Finally

 

[Hate da Bt]

Finally

Man, idiots are unbearable.

 

[Hate da Bt]

he has a better hairline than me

feels bad

feels really bad

It shouldn't.
It's all a perspective.
It's not the end of it all.

 

[Arrade]

What???
Man, I refuse to engage in this any further.
Do you!
I'm out!

I don't think calcium deposits are because of some action of the muscle - I don't follow the galea theory...

 

[Hate da Bt]

I don't think calcium deposits are because of some action of the muscle - I don't follow the galea theory...

Dude, calcification is an outcome, not a cause.
Get your sh*t together.
Have you even studied Biology?

 

[Arrade]

Dude, calcification is an outcome, not a cause.
Get your sh*t together.
Have you even studied Biology?

So are you saying that DHT causes calcification?
Or that galea stiffness causes it?


Not since high school, though I continue to read about topics that are relevant to me

 

[Hate da Bt]

So are you saying that DHT causes calcification?
Or that galea stiffness causes it?


Not since high school, though I continue to read about topics that are relevant to me

I'll try to be as simple as possible.
Calcification is the result of tissue damage or malfunctioning. It's one of the outcomes when something goes wrong.
In male pattern baldness, DHT induces the release of factors that inhibit normal hair growth. Those factors not only inhibit hair growth, but also instigate other processes, like a mild inflammatory reaction, which eventually leads to local fibrosis and calcification.
I told you you know nothing but your loserness doesn't help you see straight.
I hope you see one day.
Now, f*** off!

 

[Arrade]

I'll try to be as simple as possible.
Calcification is the result of tissue damage or malfunctioning. It's one of the outcomes when something goes wrong.
In male pattern baldness, DHT induces the release of factors that inhibit normal hair growth. Those factors not only inhibit hair growth, but also instigate other processes, like a mild inflammatory reaction, which eventually leads to local fibrosis and calcification.
I told you you know nothing but your loserness doesn't help you see straight.
I hope you see one day.
Now, f*** off!

Oh come on, I was learning so much!
Did you know the inflammation precedes the dht, not the other way around?

 

[Ayr9]

I'll try to be as simple as possible.
Calcification is the result of tissue damage or malfunctioning. It's one of the outcomes when something goes wrong.
In male pattern baldness, DHT induces the release of factors that inhibit normal hair growth. Those factors not only inhibit hair growth, but also instigate other processes, like a mild inflammatory reaction, which eventually leads to local fibrosis and calcification.
I told you you know nothing but your loserness doesn't help you see straight.
I hope you see one day.
Now, f*** off!

My f*****g god,do you even know how dht reacts with other cytokines and bullshits and attacks the hair follicles???ffs dht just doesnt randomly go and attack the follicles..It reacts with other cytokines,signalling proteins and fatty acids etc to cause inflammation..Dont you experience inflammation???And these dht response to the scalp causes bone growth,which eventually supress the capillaries in the scalp..And this causes calcified blood vessels...And fibrosis occurs when there is overproduction of collagen and fibroric tissues develop at the surrounding region of each follicle..

 

[Ayr9]

@inmyhead Alright you dont wanna believe these bullshit theories and you know kobody ever got result with it...But do you think somebody ever tried this alongside finasteride or without even trying finasteride???I saw you commented on the sandalore thread and you are willing to try it(or trying it now)...Btw do you know how it works???
It doesnt do sh*t to the dht instead it increases the igf-1 and decreases tgf beta-1 or 2..I dont remember correctly...See the picture,there you can see increase in dht causes increase in tgf beta-1...
Why dont you guys just dont understand that finasteride isnt that golden ticket???
People dont even try the theories which are posted in the internet but also b**ch that finasteride is not working and also giving them sides ffs!!

 

[ahmad029]

I'll try to be as simple as possible.
Calcification is the result of tissue damage or malfunctioning. It's one of the outcomes when something goes wrong.
In male pattern baldness, DHT induces the release of factors that inhibit normal hair growth. Those factors not only inhibit hair growth, but also instigate other processes, like a mild inflammatory reaction, which eventually leads to local fibrosis and calcification.
I told you you know nothing but your loserness doesn't help you see straight.
I hope you see one day.
Now, f*** off!

I have been suffering from PFS about last two years, I took it knowing it can cause it, I dropped it with first sign of side effects,
After stopping my side effects got severe and some new ones popped out,
I regret taking finastride every second of my life.
May be for someone lucky this is a real saviour, but one should tread it after a lot of thinking. So targeting DHT is not an optimal way it is too dangerous, they should target downstream of it.
Sorry for my English.

 

[Ayr9]

@MyThinningConfidence Please tell how were you regrowing your without using finasteride for the first few months...Please tell that there is something called mechanicl stimulation which can be induced by heavy scalp massage or wounding

 

[Arrade]

@inmyhead Alright you dont wanna believe these bullshit theories and you know kobody ever got result with it...But do you think somebody ever tried this alongside finasteride or without even trying finasteride???I saw you commented on the sandalore thread and you are willing to try it(or trying it now)...Btw do you know how it works???
It doesnt do sh*t to the dht instead it increases the igf-1 and decreases tgf beta-1 or 2..I dont remember correctly...See the picture,there you can see increase in dht causes increase in tgf beta-1...
Why dont you guys just dont understand that finasteride isnt that golden ticket???
People dont even try the theories which are posted in the internet but also b**ch that finasteride is not working and also giving them sides ffs!!

I think it comes to down to not being smart, or just fear of trying something unknown and blindly following medical authority.
It's not the current medical theory that calcification causes balding, thus it's hippie voodo; Nothing is right unless the FDA says so, nevermind the possibilty that perhaps the FDA is wrong or missing a crucial point.
DHT is the current medical theory so nothing else matters or can be possibly right.
I think these people cannot think independently

 

[Arrade]

I have been suffering from PFS about last two years, I took it knowing it can cause it, I dropped it with first sign of side effects,
After stopping my side effects got severe and some new ones popped out,
I regret taking finastride every second of my life.
May be for someone lucky this is a real saviour, but one should tread it after a lot of thinking. So targeting DHT is not an optimal way it is too dangerous, they should target downstream of it.
Sorry for my English.

You can actually target upstream by removing the inflammation that causes DHT to be activated.
In my idea, inflamed blood vessels are considered a wound by the body, then DHT and TGF-B1 are activated in these blood vessels.

 

[Ayr9]

My scalp skin is surprisingly flexible. Even where I'm thinning.
My crown is flat and that's where I started thinning
I get bleeding in the front hairline and top of the head with a 0.5mm stamp. So lots of bloodflow.
I can pinch skin all over my scalp.

Do you have receded temples???Ok if you have then look your temples,if they are slightly protuded or not???
Ok so your crown is flat??Even mine too is flat..But problem is when you pinch a large area and pull up skin,can pull up skin like it is in your neckline???A balding person cant do that but just see a boy in his 20s having a Nw1 hairline...You will see it is evenly circular and flattended but at the same time they can pinch a good amount of scalp...Not like us which is flat and uncircular and protuded...Balding scalp is very unevenly circular....But when someone go slick bald,the scalp protudes and then flattens at a typical way.....Check the differnce in temples and vertex flexibilty between a nw3-4 and nw0-1..
A balding scalp is flat but you cant pinch a good amount of skin..You can move it with your finger tips but when try to deep knead your scalp,can you pull a good amount of skin??

 

[aldog]

I never used to be able to pull a good amount of skin until I started using WAY5000. Now I play with my horns all day long!