Very interesting, thanks for sharing, I think it always comes down to growth factors and wnt, everything points that way.
Local friction -> inflammation -> wnt,
derma rolling -> inflammation -> wnt
fgf9 timed perfectly after wounding -> wnt feedback loop -> hair neo genesis
dht ultimately shut down wnt through dkk1 -> hair loss.
Anything that increases wnt in follicle has shown to increase hair growth. There is some merit to massaging causing hair growth after all but I believe it's not caused by increased blood flow, increasing oxygen supply, etc (though they may have some merits), but ultimately it seems like if the process doesn't lead to increase in wnt, then there is no hair growth.
The upregulated genes included hair growth genes such as VEGF, WNT, BMP, and PDGF, and the downregulated genes included hair-removing genes such as IL-6 and TNF.
What if instead of massaging with fingers by pressing down, you stand on your head for about 3 minutes, this way you can apply more pressure to the scalp thus flattening the head shape a little more ?
The problem with Fred is that he gives out wrong info to the "new hairloss sufferers" which he says he cares so deeply about.They won't leave this thread since it gives them that minute of symbolic power and sense that they're higher than us. What I'd like to see from them instead is more intelligent skepticism. Real arguments as opposed to sterile cynical sarcasms. They're like the two old guys in the Muppet show. I think we should simply ignore their posts.
I can't say why scientists don't, but then again, there are many topics which I would like to have primary-researched by knowledgable people. Often, even with scientists, it's a matter of plausability. When you develop a new theory, it needs to seem plausible to yourself to actually do research on it (otherwise science would just blindly strive in random directions which would only turn up useful results by accidents). Androgens potentially being involved in skull growth is, or so I'd guess, nothing that would "pop to the mind" of dermatologists.I don't understand why they don't give more credit to the hypothesis of skull growth. My scalp feels thinner and harder than anywhere else on my body and I can't imagine it's actually thicker and giving its shape to the top of my head. My head is shaped like the sugar mountain in Rio, and I noticed that like 5 years ago. I had started practicing yoga and doing the headstand position. I stopped doing this central posture of yoga culture because my skull was not flat and pressing my whole weight on it felt too painful. I was also less stable. But I thought I always had this head shape and didn't think male pattern baldness could be involved in it.
Then take your own advise and stop pointlessly commenting. Guess what, it is our own choice if we want to debate here and spend the time here or not.And it will be harder for you since you will also realise you lost so much time of your youth on those forums pointlessly debating, you'll never get that time back.
i had no intention on posting anything because of all the know it alls who have no open mind and are only interested in scientific proof of treatments and what not, you people piss me off,