You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an alternative browser.
You should upgrade or use an alternative browser.
Doctor discusses Finasteride on radio
- Thread starter Wuffer
- Start date
Haha, right. Funnily enough, finasteride hasn't affected my energy levels in any way.. In fact for the last month i've been training almost daily for some mountain bike races coming up this summer, and i'm happy to say my endurance is just as good as it was when I was 20. Though it probably helps that I don't do drugs anymore and drink about half as much as I did back then.. Not to mention i'm making great gains lifting weights at the gym.. I've also lost close to 20 lbs since the beginning of the year. The whole 'weight gain on finasteride' thing was initially troubling to me when I first started, but I haven't had a single problem dropping the pounds.
Bring it on, summer!
Bring it on, summer!
StoptheMadness
Established Member
- Reaction score
- 0
the next few paragraps in that article are critical of Traish....finfighter said:The following is from a new WebMd article from this month, which is based on the research of Abdulmaged M. Traish, PhD, a professor of biochemistry at the Boston University School of Medicine..
Source- http://men.webmd.com/news/20110309/sexu ... gs-persist
... But the review says less attention has been paid to uncommon but potentially devastating side effects of these medications.
Those side effects can include anxiety, depression, loss of sex drive, difficulty getting or maintaining and erection, gynecomastia (growth of male breast tissue), and reduced semen production, which may affect fertility.
What’s worse is that for some, these side effects persist, even when they stop taking the medication, according to the review.“
We don’t really understand why, but the symptoms remain persistent or irreversible and even if they get off the drug,†says study researcher Abdulmaged M. Traish, PhD, a professor of biochemistry at the Boston University School of Medicine. “They no longer regain what they had before. Biologically, something gets shut off and gets shut off once and for all.â€
Traish thinks that may be because nerves that are maintained by dihydrotestosterone become permanently degraded and can’t be repaired even after men come off the medication.
"Critics of the paper, however, called its conclusions biased and bizarre.
“If you subtract the placebo group, 3% to 4% of patients may have some sexual side effects, and they go away when you stop the drug,†says Patrick Walsh, MD, the University Distinguished Service Professor of Urology at Johns Hopkins in Baltimore, who also reviews studies for the journal Urology. “This is bizarre.â€
“I’ve never seen a patient who had sexual side effects and when he stopped them he was impotent forever,†says Walsh.
When asked if he gets any financing from drug companies, he said, “Absolutely I do not. No.â€
Walsh has researched the effects of 5-alpha-reductase inhibitors for 42 years and recently testified in FDA hearings against their proposed use for prevention of prostate cancer.
“If you take a look at the randomized, controlled trials, something like 3% of placebo and 6% of treated patients will have some sexual side effects,†Walsh tells WebMD. “It’s one of the reasons why patients discontinue the drug and when they discontinue it, the problem goes away.â€
A different research article below is from 3 years earlier than the above study....
http://www.andrologyjournal.org/cgi/content/full/29/5/514
The conclusion from this article is:
"We conclude that 5 {alpha}-reductase inhibitors do not lead to erectile dysfunction to a significant degree, and we support the position that dihydrotestosterone is less relevant than testosterone in erectile function."
What I thought was strange was that the research abstract I linked to and the article that finfighter cited has a certain "connection" between the critics of finasteride causing ED
..........What is up with the Urology department at Johns Hopkins? !!!!!
I would probably have strangled her if I was in the same room listening to her - when she was suggesting that it's all placebo, and laughing when someone claimed that they had several side effects within the first week. However, I do believe that only a small amount of people experience severe side effects from Propecia, and she really opened my mind when it comes to a "medical perspective". Say you have 80.000 patients which are using a drug without any problem; then a 1500 people who gets their lives ruined, is acceptable.
We'll see how acceptable that is, when those 1500 people are suing.
We'll see how acceptable that is, when those 1500 people are suing.