Dutasteride

[WiseJoeyD]

Again thanks for the help. Any particularly glowing sings that it was working....like suddenly being able to grow a giant mullet or something?!

I've always wondered if there was eer any reports or inveetigations into gneric dutasteride (or even finasteride) that showed that they were just as good/worse than the "Offcial" version of the drug? Dr Reddy's seems to be mentioned a lot in term sof producing gneric dutasteride;was there ever anythin less than glowing[there's that word again!] reports about their Generic drugs?

 

[dan8909]

just wondering how much dutasteride someone would need to take to get the equivilent of a finisteride dose.
one 0.5mg pill every 4 days? would that be about right?
i want to be careful with this stuff, and take less then people are talking about.

 

[mvpsoft]

If you're going to take small doses of dutasteride to equal the dosage level of finasteride, why don't you just take finasteride?

 

[dan8909]

cant someone just answer my question? instead of answering a question with ANOTHER question.

 

[Hollywood7]

regarding Buffboy's comments

Buffboy what is the information of effects to the scalp if you are talking 2.5mg finasteride is it more than tak .5mg of dutasteride what about 1.0mg of dutasteride.

Here is the info that Buffboy posted before which is very helpful....anyone know where this info came from or where it can be found....many thanks.

0.5mg Dutasteride inhibits ~ 92% serum DHT and 55% scalp DHT
2.5mg Dutasteride inhibits ~ 95% serum DHT and 82% scalp DHT

This basically means, that you will achieve significantly better results by taking five capsules a day than only one. Because it's the scalp DHT you have to reduce.

So what I'm saying is that I think taking 2.5 mg Dutasteride a day is being VERY close to a cure against hairloss for MOST people.

But as seen below you will still supress scalp DHT much better using 0.5 mg Dutasteride a day than taking 1 mg Finasteride.

1.0 mg Finasteride inhibits ~ 70% ser

um DHT and 38% scalp DHT

 

[Buffboy]

Here I am again. Just Google your question.

Below is listed some of the sources saying what I did:

http://hairsite2.com/library/article226.htm
http://www.hairlosstalk.com/newsletter/article189.htm
http://www.regrowth.com/hair_loss_treat ... esults.cfm
http://www.hairsite7.com/m606dutas30/_d ... 000072.htm

Hope this is enough - I could continue all night long.

But I have become smarter since my last post. Back then I was being very logical, I know now that the human body isn't logic. There is more to hairloss than DHT. The more you lower your DHT levels, the higher your Testosterone levels get. Testosterone seems to play a direct part (as well as indirectly) in hairloss.

EDIT: Oh, forgot to answer your question: It seems that Finasteride is a none-dose related drug, meaning that you will not get significant better results by taking a higher dose.

 

[Hollywood]

dutasteride VS finasteride

Well, the problem I am having is that since I switched to Dutasteride about 7 months ago my frontal hairloss has been increasing much more that it did when I was on Finasteride. Very difficult pill to swallow if you know what I mean...why did finasteride work better than dutasteride if it stops more DHT.

When you say dutasteride is more effective reducing DHT at the scalp could it be possible to say that it is more effective at a particular PART of the scalp like the vortex as opposed to the frontal areas. Maybe finasteride does a better job at the front and dutasteride at the rear vortex.......possible?

Thanks for the input. I have increased my dutasteride dosage now to 1mg per day if I don't see any results changing within the next month I'm going back to finasteride as it seemed to work better. I've also read at other links about people losing their hair at the front when using dutasteride switching from finasteride. Maybe dutasteride isn't the wonder drug we think it is and this is why the manufacturer doesn't put it to market as a hair drug.

 

[Buffboy]

As I tried to say, it seems that the frontal region often is more sensible to testosterone than the rest of the scalp. So when you're on Dutas you block so much DHT, and that testosterone that normally would convert into DHT is now free. This means that Testosterone levels rises with 50% compared to being on finasteride.

I think this is the reason. That's why I'm switching back to finasteride ASAP.

 

[mvpsoft]

As I tried to say, it seems that the frontal region often is more sensible to testosterone than the rest of the scalp. So when you're on Dutas you block so much DHT, and that testosterone that normally would convert into DHT is now free. This means that Testosterone levels rises with 50% compared to being on finasteride.

Is there any evidence for this conclusion, or is this just speculation? If speculation, is it based on anything more than your own experience?

 

[Buffboy]

"So when you're on Dutas you block so much DHT, and that testosterone that normally would convert into DHT is now free. This means that Testosterone levels rises with 50% compared to being on finasteride."

The above statement is based on facts. The thing about the frontal region being more sensitive is pure speculation.

 

[mvpsoft]

I know that free testosterone rises. I was wondering why you think that causes hair loss, especially along the hair line/temples. So thanks for clearing up that it was simply speculation.

 

[Buffboy]

Well it's speculation, but I read somewhere, it was some dr.'s theory.

 

[Guest]

I sure hope that it's not correct... testosterone hurting frontal baldness... Has anyone else had this effect from dutasteride?

 

[Slartibartfast]

At the risk of being over-simplistic... I suspect that the comparatively heavy frontal loss suffered early on by those who, like me, switch from finasteride to dutasteride is nothing more than a shed.

For me, finasteride was very successful for the bulk of my hair but failed to work at the front. Now, presumably this was due to the frontal region's follicles requiring a greater reduction in DHT than it could provide. So, when I switch to Dutasteride which follicles will be affected by a significantly lowered level of DHT? Yes, that's right, the ones at the front that were still being damaged by it - hence the shed.

Probably.

Slarti

 

[Buffboy]

Do you have backing for this theory - I have thought of this myself. Would be nice to hear from someone science dude. :lol:

 

[Slartibartfast]

It's pretty much pure conjecture on my part, with just a smidgin of logic thrown in. Over the next couple of months my own hair's progress (or lack of) should help settle the matter and, for what it's worth, the early signs look encouraging.

Slarti

 

[moegreen]

around when will dutasteride be available for hairloss (like proscar --> propecia)?

 

[outgrowth]

unknown.. maybe never :!: :hairy:

 

[VOVVIE]

i wouldnt get my hopes up for any kind of cure for baldness, ever.

 

[outgrowth]

vovvie.. stem cells are the cure (hair cloning) :wink:
but it will be only available in 20 years or more, unfortunately.. (people may say 5, 10 years, but that's too optimism)