Exploring The Hormonal Route. Hair=life.

Ephemeral-Kitten

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I am sorry but I am an androgynous-identified individual who uses male pronouns for convenience.
I worship Hecate; hence Willow. I succeed to no one nor am I associated with anyone nor with any treatment in general.

Homo homini lupus.
Okay poster-formerly-known-as-Janey, would you prefer Will? It's more androgynous than Janey or William.
 

Ephemeral-Kitten

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One would need to cease meds and then back up sperm. Most transgender people get breast implants but you are correct that most of those who do not seek surgical augmentation tend to be smaller than XX's. I have seen plenty of chicks with say, A cups to C cups. It would depend on the body type but smaller XY's ought to be more concerned with breast growth because it is all but impossible to hide on a petite frame.
Even on a small frame sometimes the development is such that it's easy enough to hide.
 

Willoway

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Okay poster-formerly-known-as-Janey, would you prefer Will? It's more androgynous than Janey or William.
Will is fine as Buffy used to call Willow "Will" all of the time but I don't want to be encumbered by anyone's former baggage. This HRT stuff is not self-evident related to where hair stops and emotional changes associated with being XX begin.
 

Willoway

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You need 300pg / ml + and T <50ng / dl. This is the formula for hair growth success. This cannot be achieved with AA alone. I tried to use Bicalutamide with Finasteride in doses up to 100mg, but it doesn't work.
Hmm. I think that it was someone else who provided that rule of thumb about E2 and T thresholds, although some might say going down to T<10 ng/dl is even more bodacious. Also it was someone else who was adamant about the merits or lack thereof, of single-shooting AA's without estrogen, meaning mediocre hair results at best. Single-shooting E2 on the other hand, is to be at the height of all great theoretical hair formulas.
 

Howdy Partner

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Topical bica is probably a better option than topical E2. For one, E2 has a small molecular mass and will go systemic easily, much like topical finasteride, so you might as well take it orally or inject it. Also, the carriers themselves don’t keep it in the dermal layer long enough to target the tissues. Bica has a larger mass, but still well under 500 so that is quite favorable. Not only is it good at crowding out the AR, but it should also encourage an increase in local E2 levels. The problem is its poor solubility but you can mitigate this with needling and using a pure ethanol vehicle. Its very long half life makes it a convenient option too.
 

keepcoolmybabies

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Will is fine as Buffy used to call Willow "Will" all of the time but I don't want to be encumbered by anyone's former baggage. This HRT stuff is not self-evident related to where hair stops and emotional changes associated with being XX begin.
I do love me some buffy
 

John Difool

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I am afraid that needling will kill follicles! I know it is bro science ! I am Norwood 0 in front and more hair than i need only this thinning on crown
You don't need to specify that you are a broscientist with statements like that. But even broscientists should know better.
 

Willoway

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I found the Magicks on that show fairly interesting. Hecate bless. I love watching you fight with all of the trolls, KCMB. You don't give an inch and you are immaculate and sure in your gender stead. Would that it were that easy for Janey.
And I totally know what you mean by the guys acting like 2nd graders. You know most of them find you hot; you have mirrors. But then they have to cut you down somehow to purge rejection and try to lower you to their level in their so-to-speak minds.

When Janey took off, several people made comments about her big behind that were seemingly rude but not really. Not to mention that to Janey, having a big behind was a key pillar in life.
 
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John Difool

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Topical bica is probably a better option than topical E2. For one, E2 has a small molecular mass and will go systemic easily, much like topical finasteride, so you might as well take it orally or inject it. Also, the carriers themselves don’t keep it in the dermal layer long enough to target the tissues. Bica has a larger mass, but still well under 500 so that is quite favorable. Not only is it good at crowding out the AR, but it should also encourage an increase in local E2 levels. The problem is its poor solubility but you can mitigate this with needling and using a pure ethanol vehicle. Its very long half life makes it a convenient option too.
Topical bica is not recommended. Any AA with such an extremely long half life will build up in the scalp. That't the reason Bica never kicked as a topical like Daro, Enza, etc. The only AA I would suggest could work as topical are acting as AA degraders. Bica as a topical is very bad idea.

E2 topical hits ERb which benefits hair growth but also hits equally ERa which puts your hair from anagen to telogen very raplidly in overdrive mode. If your goal is to grow very short hair (2-3mm) and have them fall out right away, then by all means, try E2 topical and repeat the cycle so you exhaust your hair follicles, E2 is definitely a good way to achieve that. You may get early growth but that will quickly be replaced by hair falling out. There are people experimenting with microdosing E2 on scalp on this very forum, which may work similar to E2 serum blood level of HRT. We are talking mcg here not mg. Similar to Bica, E2 topical is a very extremely bad idea to keep your DHT sensitive hair.

A better option is to stick to RU and E3 as a cocktail addition to your minoxidil.
 
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Willoway

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I think the only risk to damage would be if you needle beyond a standard depth
I am doing both now, derma-rolling and Dr. Pen. I think both are excellent but the Pen is far better for facial tissue. I am mainlining Retin-A and Estrogel and my face looks like a boy's more than a female but definitely it's an improvement. I had to do more electrolysis on my face after using oral min for almost a year but eh, it was worth it. Now I take one drop a day but I use topical for needling and mix that with huge dollops of retin-y A goodness.

Dermal rolling and micro needling can grow new scalp hair out of scar tissue. I do my entire head and I can clearly see my donor area filling in with blonde hair. It's all blonde for some reason, the new growth. So micro needling can rejuvenate plugs on top and also heal and reiterate new terminal hair from scar tissue in the sidal patterns. Microneedling is someone's gift from heaven; it actually works to remove wrinkles and imperfections and with estrogen and retin A, the results can be striking. Together with beard removal, my youth effects continue to be staggering but I am just waiting for the temples to go terminal. It's a done deal though as both are covered in whitish-downey hair. Goddess, it takes forever to grow hair out from bald so I am still at a guys' length bob but the forehead is the biggest give away in certain lighting. Say McCartney in Get Back length. Boy is that a hair and attractive male fiesta.

Some times I felt that my results were unattainable.
 
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Howdy Partner

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Very good. The amounts used are so small that liver toxicity does not play a role, and there are some reports available of very good results with topical Bica. The main problem is solubility, which is very poor. DMSO should not be used in my opinion (furthermore, it makes you and everything you excrete smell like rotten eggs), which leaves a pure ethanolic vehicle. Since the half-life is so long, a good protocol would probably something along the lines of:

1mg/mL Bicalutamide in 98% ethanol (maximum solubility)
Once or twice per week, light needle the scalp with 0.3-0.5mm needles. Apply Bica solution generously. Scalp should be dry within a minute again. Should not take very long either, maybe 5 minutes give or take.


This is simply not true. You are projecting your n=1 case to all male pattern baldness sufferers, which is not only wrong but also dangerous. Bica may not have "worked" for you (although I still think you terminated the experiment way too early), it can and will still work for many others. I feel sorry for you that you have had to resort to HRT to get your desired results, but fact is that the majority of people will not need it to get very satisfactory results. We do not know if we can completely eliminate DHT in the scalp, but topical Duta (possibly in conjuction with oral Duta) should come pretty close. I also disagree that HRT cycles would be safer than Nandrolone. Nandrolone is actually a bioidentical compound, found in minute amounts in the body. The skin metabolizes Nandrolone to DHN which is much less androgenic than DHT or Nandrolone itself. You cannot use 5AR inhibitors on Nandrolone monotherapy, because this conversion would be inhibited. HRT cycles are not safer because:

1. E2 is used in supraphysiological amounts; E2 is dose-dependently carcinogenic
2. Large hormonal shifts are unhealthy for literally every structure in your body

Cycles are not sustainable and should not be done. If you want to get on HRT, use physiological dosages and stay on it for life. Nevertheless, I admire your willpower and consistent documentation.

By the way, eliminating all gonadal androgens does not get rid of adrenal androgens. There will always be conversion to DHT.
Just gonna repost this from the legend
 

John Difool

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You can safely drop the derma rolling if you have a Dr Pen. In fact do it in the name of safety. Wounding by tearing is worse especially when you have a dermapen.
 

Howdy Partner

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I am not knowledgeable on AAS at all outside of Testosterone. You could search Reddit or any AAS forum for anecdotal reports. I believe Anavar should be quite hair friendly, since some women use it as well. Same for Boldenone. To be frank, I would never recommend steroids just like I would never recommend HRT for non-trans people. I am very aware on anything anti-aging, and AAS definitely do not fit into that picture. Administering exogenous T is already pushing it for me. I think the only anti-aging hormones are Pregnenolone, Progesterone, DHEA and Thyroid. The rest just ages you more rapidly (in supraphysiological doses, as always).

There is an older thread by IdealForehead that sums up the differences pretty well. Bica's massive half life is really favorable here, because RU has a meager half life of one hour (serum). Furthermore, Bica's binding kinetics are also far superior to RU. Basically, I see no reason to use RU at all. It is not safe, and there are many safer and more effective AA's available. I believe RU got introduced by influencers some years back, and that is where the hype originated. Not that it is not effective: it is just less effective and less well researched than other options (which are also FDA approved). I see no reason to use RU and Bica concurrently. The only thing I would keep an eye on with Bica is systemic build-up due to its half-life, however, that should be avoided with once or twice weekly applications. Daro would probably be even more effective, but it is also (a lot) more expensive.
RE: RU
 

John Difool

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So many people are using very bad treatments on this forum with no idea about the reason it can't work. Some are even stubbornly not reading advices from people who know a little more. These people deserve to bald because they act stupid. But this section of the forum is even worse than that. Now you got people with no clue whatsoever who have at their disposal HRT to solve their baldness issue. What a circus!
 

Willoway

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You can safely drop the derma rolling if you have a Dr Pen. In fact do it in the name of safety. Wounding by tearing is worse especially when you have a dermapen.
The variable here is that a stamper is likely to be best when treating areas with large amounts of scar tissue because of the pressure that is pressed into the scar. I have all of these circular scars and they all are productive with hair so that's the main reason why I might still do both but things have improved so much that it's only the hairline and there's no scar tissue in the "original" hair line which had a large cowlick in front.

Why duta plus finasteride? My insurance covers both even at the same time. So if finasteride is 70 percent effective and duta 90 percent that's 160 percent and I love those odds. To me, they might each work slightly differently and they could have some sort of interaction but I don't need either most likely but backdoor pathway and all of that as I sit at 4ng/dl. I doubt losing here at 4ng/dl is even possible, knock on wood, Hecate!
 
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