Exploring The Hormonal Route. Hair=life.

[SavingMyHair]

Maybe it's from bicalutamide or dutasteride. don't take it all at once to know what's stopping your hair.

Why would them cause miniaturization when peripheral androgens production are almost non existent?

 

[Almas_NW0]

E2: 330 pg/ml
3 a diol G: 49ng/dl

Still miniaturization going on with these values. This is just impossible.

T level?

 

[likemike]

Hm okay... I have been on oral minoxidil for 3 years now, estradiol/bicalutamide/dutasteride for 5 years. And... Ive been experiencing diffuse hair loss. Could it be a cyclic shed from the oral minoxidil?

Thyroid gland? T3? Need some Jod?
Too much estradiol makes shedding and thin yellow hair too.

 

[Fvgwnx]

Why would them cause miniaturization when peripheral androgens production are almost non existent?

bicalutamide and dutasteride increase T. and hair is fucked

 

[SavingMyHair]

bicalutamide and dutasteride increase T. and hair is fucked

They cant increase T when you have high E2. It only increases T when male gonads are functioning.

 

[SavingMyHair]

T level?

Havent done T. Last time I did it was at 180 ng/dl but my e2 was at 20 pg/ml(that was 8 months ago and I was using a sh*t e2 spray, now I'm using Een Injections). Now that I have 330 pg/ml + very low 3a diol g, my T must be in female ranges. I barely have any sperm production and it is very very wattery so that's another thing of low T.

 

[Get my hair back]

I think the question is more about DHT, not T? Because, on my estrogen injections, my testotheiron was below the castration level and my DHT was high.
These are my numbers.

 

[SavingMyHair]

I think the question is more about DHT, not T? Because, on my estrogen injections, my testotheiron was below the castration level and my DHT was high.

A diol G is very low, that means androgens on peripheral tissue (hair for example) is very low so I should not have hair loss with those levels.

 

[Get my hair back]

Okay. Can you track the level of PRL or density of PRLR in the skin, without biopsy?

 

[Get my hair back]

The standard pattern of alopecia is not just T and DHT.

 

[SavingMyHair]

The standard pattern of alopecia is not just T and DHT.

I know but my case is weird. I recovered all my hair once on dutas + minoxidil, but after a while dutas stopped work and my dht was high even on dutas.

 

[Get my hair back]

What are you doing now to suppress DHT?

 

[SavingMyHair]

What are you doing now to suppress DHT?

Estradiol injections, dutasteride and bicalutamide

 

[Get my hair back]

Estradiol injections, dutasteride and bicalutamide

And the tests systemic DHT decreased?

 

[Get my hair back]

We need to pressurize DHT not only in the periphyric tissues, but also systemically.

 

[SavingMyHair]

And the tests systemic DHT decreased?

I dont know now. When I had 1011 T induced by dutas and before HRT, my DHT was 59 ng/dl. After starting HRT with CPA + shitty e2 spray (180 ng/dl T and 20 pg/ml e2) my DHT decreased to 39 ng/dl(still high). Now with injections plus bicalutamide im pretty sure those level has to be even lower, because everything changed: less body odor, very slow growth and less body hair/beard growth, no oily skin, no sperm at all etc. With that and low 3 a diol g, I can guess my DHT is under 10 ng/dl now.

 

[SavingMyHair]

We need to pressurize DHT not only in the periphyric tissues, but also systemically.

Yeah but peripheral could be even more important. The user @GRme11 is one of the best examples. When he recovered his hair, he had high DHT levels but his 3a diol g was low, so he recovered his hair. Now his 3 a diol g spiked and he is losing his hair very very fast and aggressively.

 

[Get my hair back]

Absolutely. But Androgenetic Alopecia on systemic 10% DHT can progress, with high receptor sensitivity.
People with 5AP deficiency don't get baldness.

 

[dar3k]

Hi, maybe some of you guys remember me… So I decided to give a try to HRT to save/reverse my hairloss. Unfortunately NOTHING works on me.

I have been on 50mg bicalutamide ed + 4 mg estradiol + 10mg oral minoxidil ed + 0.5mg dutasteride ed + 1mg finasteride ed + 150mg RU58841 + 20mg Pyrilutamide (2 x 10mg) + Topical minoxidil 2 x day + Rosemary Oil ed

My blood test after 1 month on HRT:
T: 1.5nmol/l
E2: 239 pg/ml
DHT: 39pg/ml

After 3 months:
T: 0.9nmol/l
E2: 289pg/ml
DHT: 26pg/ml

After 6 months:
T: 0.6nmol/l
E2: 233pg/ml
DHT: undetectable

I also did a blood test for thyroid tsh, ft3, ft4, ferritin, iron, b12, prolactin and everything was fine.


It slowed down a bit my hair loss but after 8 months my hairs are thinner. My crown is much thinner, still receeding, temple peaks literally disapeared, my hairs are still miniaturizing.

All I want to say to you guys, HRT - even with proper female levels, even with undetectable DHT values is not guarantee to hairloss. As you can see for example on Reddit /femalehairloss a lot of women with normal female hormone levels are going bald too. They have diffuse thinning/female pattern baldness/receeding hairlines etc.

If you want to try HRT/pyrilutamide/RU etc. of course you can do it, but remember that there is no GUARANTEE to stop/reverse hairloss.

 

[Get my hair back]

It is possible that the PRL/PRLR in the skin is off the charts and any method, even HRT, will be powerless.
And maybe it is something autoimmune, have you tried topical immunosuppressants?