Exploring The Hormonal Route. Hair=life.

[Itsnoahkennedy]

besides theres got to be a labrat for this one too
Also I read Rob Lowe took finasteride through his veins. Idk how true that is.
https://www.hairlosscure2020.com/page/3/

i believe you can only take micronized drugs sublingually ?

 

[Itsnoahkennedy]

2030!!! That is after my youth would have been ended. Don't need that. I need my hair now. hair loss has been f*****g my life ever since I was 14. I've had girlfriend for 3+ years with whom I broke up because I thought I've some dangerous diseases causing hair loss. I know stupid, but I was a kid and didn't know anything about Androgenetic Alopecia - even today when you Google about hairloss you won't find anything about diffuse thinning or dupa; it has to be either male pattern baldness or Areata, else it's just in your mind. Rant over. I'm little high now, it seems.

I know your pain man, i started losing mine later than you, at 17 years old, but the stress of balding has taken a toll on my mental health. It became an obsession to get my hair back, i spent a lot of money on doctors who did no help, some "hair specialist" even scammed me for $2,500 and i knew it might be a scam but that's how vulnerable i was because i was desperate. I tried Finasteride which did nothing. I tried Dutasteride which did nothing. i tried topical minoxidil which maintained for a while but eventually did nothing. For the first 3 years i was so stressed out that towards the end when i knew none of those meds were working in my body i would go into full blown psychosis where i would feel panicked with anxiety and have many hallucinations where i would feel like i am having a bad acid trip. It sucked me dry of emotions and i can't feel enjoyment in anything at all no matter what it is, people said get out and travel, so i traveled the world and got no enjoyment out of it, and i think balding has altered my personality in a way that i am bitter inside and i also lost my long time girlfriend because of it (i assume). I live in isolation to this day because of it. i don't go outside or talk to anyone unless i have to. i guess it depends from person to person but balding can literally destroy ones life. HRT is the last hope for myself, i said the same, i choose side effects over depression because i don't want to feel like a piece of sh*t anymore.

 

[Itsnoahkennedy]

I am asking this question to all of you that, after starting anti-androgen, has anyone ever told you that you have started to look like a girl? Please respond.

Lmao, yeah yesterday someone said my skin is starting to look feminine, but if i turn out looking like a girl, then oh well i don't care.

 

[itchymadscalp]

He has actually been banned for starting too many threads, he has told me.

Ok that's stupid then ... I don't agree all the time with him but when you're contributing to the forum you're not supposed to be banned ...

 

[Ikarus]

I know your pain man, i started losing mine later than you, at 17 years old, but the stress of balding has taken a toll on my mental health. It became an obsession to get my hair back, i spent a lot of money on doctors who did no help, some "hair specialist" even scammed me for $2,500 and i knew it might be a scam but that's how vulnerable i was because i was desperate. I tried Finasteride which did nothing. I tried Dutasteride which did nothing. i tried topical minoxidil which maintained for a while but eventually did nothing. For the first 3 years i was so stressed out that towards the end when i knew none of those meds were working in my body i would go into full blown psychosis where i would feel panicked with anxiety and have many hallucinations where i would feel like i am having a bad acid trip. It sucked me dry of emotions and i can't feel enjoyment in anything at all no matter what it is, people said get out and travel, so i traveled the world and got no enjoyment out of it, and i think balding has altered my personality in a way that i am bitter inside and i also lost my long time girlfriend because of it (i assume). I live in isolation to this day because of it. i don't go outside or talk to anyone unless i have to. i guess it depends from person to person but balding can literally destroy ones life. HRT is the last hope for myself, i said the same, i choose side effects over depression because i don't want to feel like a piece of sh*t anymore.

I understand that, although I was reasonably quick to get myself onto such an extensive regimen. Originally, I had a bad feeling about using finasteride; my instinct became reliable in this instance, because I began to notice there is a lack of success stories when it comes to younger patients in a similar situation to mine. Even now, I have a greatly bad feeling about the use of finasteride, And, I experienced that too! It became overly exhausting, and I felt detached from the world. It was as if I was watching myself in a nightmare, but I couldn’t wake myself up. It would worsen after I had gotten a haircut, because I can see how bad my hair truly is! I just felt like the world was against me because there is constantly challenges thrown at me...

 

[I'mme]

I understand that, although I was reasonably quick to get myself onto such an extensive regimen. Originally, I had a bad feeling about using finasteride; my instinct became reliable in this instance, because I began to notice there is a lack of success stories when it comes to younger patients in a similar situation to mine. Even now, I have a greatly bad feeling about the use of finasteride, And, I experienced that too! It became overly exhausting, and I felt detached from the world. It was as if I was watching myself in a nightmare, but I couldn’t wake myself up. It would worsen after I had gotten a haircut, because I can see how bad my hair truly is! I just felt like the world was against me because there is constantly challenges thrown at me...

I guess I'd again be able to become normal. I don't know if I'm originally an introvert or I just turned one BC of Hair loss. But it gave me bouts of depression, so I'd like to think I'm ambivert. I hope I can be normal again.

You're quick? Still you lost huge density. You can't add growth stimulant for reasons otherwise your progress can be fast.

 

[I'mme]

I know your pain man, i started losing mine later than you, at 17 years old, but the stress of balding has taken a toll on my mental health. It became an obsession to get my hair back, i spent a lot of money on doctors who did no help, some "hair specialist" even scammed me for $2,500 and i knew it might be a scam but that's how vulnerable i was because i was desperate. I tried Finasteride which did nothing. I tried Dutasteride which did nothing. i tried topical minoxidil which maintained for a while but eventually did nothing. For the first 3 years i was so stressed out that towards the end when i knew none of those meds were working in my body i would go into full blown psychosis where i would feel panicked with anxiety and have many hallucinations where i would feel like i am having a bad acid trip. It sucked me dry of emotions and i can't feel enjoyment in anything at all no matter what it is, people said get out and travel, so i traveled the world and got no enjoyment out of it, and i think balding has altered my personality in a way that i am bitter inside and i also lost my long time girlfriend because of it (i assume). I live in isolation to this day because of it. i don't go outside or talk to anyone unless i have to. i guess it depends from person to person but balding can literally destroy ones life. HRT is the last hope for myself, i said the same, i choose side effects over depression because i don't want to feel like a piece of sh*t anymore.

Hi5 for last sentence - I can live with some sides, but not with depression, and I'm absolutely certain of my hair continue to fall and no regrowth take place, I will be in depression.

Re finasteride and dutasteride: some people's hair is sensitive to T, and in these cases finasteride/dutasteride can even exacerbate hair loss. I do hope though that this is not true in my case.

 

[Itsnoahkennedy]

Hi5 for last sentence - I can live with some sides, but not with depression, and I'm absolutely certain of my hair continue to fall and no regrowth take place, I will be in depression.

Re finasteride and dutasteride: some people's hair is sensitive to T, and in these cases finasteride/dutasteride can even exacerbate hair loss. I do hope though that this is not true in my case.

it seemed to me as soon as the doctor precribed me finasteride my hairfall became infinitely worse and it never recovered lol. but have a look at this https://www.ncbi.nlm.nih.gov/pubmed/15464773

It's a comparison of Finasteride and Cyproterone Acetate/estrogen effect on hormone levels

"the two treatment methods was similar (47.6 % vs. 51.1%; P=0.2). Treatment with CPA plus EE2 significantly decreased serum total and free T, A, DHEAS, and DHT and increased SHBG levels. Finasteride significantly increased total T but reduced DHT levels." i think i am sensitive to both T and DHT and that's why my hair didnt have any improvement from 5AR inhibitors alone.

 

[I'mme]

it seemed to me as soon as the doctor precribed me finasteride my hairfall became infinitely worse and it never recovered lol. but have a look at this https://www.ncbi.nlm.nih.gov/pubmed/15464773

It's a comparison of Finasteride and Cyproterone Acetate/estrogen effect on hormone levels

"the two treatment methods was similar (47.6 % vs. 51.1%; P=0.2). Treatment with CPA plus EE2 significantly decreased serum total and free T, A, DHEAS, and DHT and increased SHBG levels. Finasteride significantly increased total T but reduced DHT levels." i think i am sensitive to both T and DHT and that's why my hair didnt have any improvement from 5AR inhibitors alone.

Yesss..

Have you seen any improvement yet?

 

[Itsnoahkennedy]

I stopped topical minoxidil about a month ago so i'm still experiencing the shed from that. I've been on Cypro + Estrogel since the time i stopped using minoxidil. results will most likely become noticeable in 60 more days. I'm about to start on 50mg Bical consistently everyday and results should really start popping up. ill post pics when i have something to show.

 

[Itsnoahkennedy]

I've gone from eating once a day to eating like 5 meals a day, i am so HUNGRYYY. I could eat an elephant frfr lol.

Btw @Ikarus i have the same white sandy type dandruff you were talking about a few weeks ago. did yours go away ?

 

[Itsnoahkennedy]

@LEXUS I think it would be benificial for you to read this paper written about CPA before you continue with taking high doses of the drug (read paragraphs from the right side to the left side starting with the introduction)
This information is important to keep in mind when you are taking CPA without doing research on it's phase trials. (im assuming you haven't read it before)

Title: The DNA damaging drug cyproterone acetate causes gene mutations and induces glutathione-S-transferase P in the liver of female Big BlueTM transgenic F344 rats.

Although the study was done on rats liver, it is still good information to have when you are considering very high doses of CPA. The term liver damage includes cancer, cell/gene mutation, high liver enzyme and the list goes on.

https://academic.oup.com/carcin/article-pdf/19/2/241/19258155/190241.pdf

See - "Results Mutagenesis assay The experiments performed in this study reveal that CPA was a mutagenic compound in rat liver. In experiment 1, performed with one animal per dose and expression periods of 11 and 22 weeks, a dose of 100 mg CPA/kg b.w. was found to increase the mutation frequency determined in the controls by a factor of almost 4, while doses of 25 and 50 mg CPA/kg b.w. were ineffective, with the possible exception of 50 mg CPA/kg b.w.

11 week assay time (Table I). Experiment 2 performed with five animals per dose group and an expression period of 6 weeks revealed a dose dependent increase of mutation frequency at doses between 75 and 200 mg CPA/kg b.w. (Figure 1, Table I). Mutation frequencies determined at doses of 25 and 50 mg CPA/kg b.w. did not exceed those determined in control animals. For interpretation four common dose–response models were employed to fit the data.

For the 6 week assay, Figure 1 presents a plot showing the observed proportions of mutants of the individual rats, the pooled proportions and the four dose–response models fitted. The linear model (Model 1) produced the worst fit to the data. Models 2 and 4 are better than Model 1 and indistinguishable from each other. The linear E-NOEL model (Model 3) fits the data even slightly better than Models 2 and 4. The overall lack-of-fit statistics support these observations. For Model 1 the deviance has an associated p value of 0.03 indicating" (page 242)

 

[bridgeburn]

 

[bridgeburn]

June 2017 -------> June 2019

 

[Itsnoahkennedy]

June 2017 -------> June 2019
View attachment 122022

stunning!!!

 

[Yar]

June 2017 -------> June 2019
View attachment 122022

Bridge, what do you say about the addition of progesterone? Topical therapy with progesterone significantly inhibits 5α-reductase in an in vitro study. According to Cassidenti D.L. et al. (1991), in high concentrations, progesterone inhibited the synthesis of DHT by 97%, estradiol - by 41%. I am going to use it in a gel on a body of Estrogel type

 

[Yar]

estradiol thickens the hair during pregnancy, women, respectively, should be present progesterone

 

[Yar]

Progesterone, the female natural ovarian hormone, which is high after ovulation, not only does not have androgenic effects, but also prevents them. In fact, by suppressing the levels of luteinizing hormone (LH), it reduces the stimulation of tech cells (which produce the male hormone) in our ovaries. Progesterone also reduces the conversion of testosterone to dihydrotestosterone (DHT), a male hormone that directly causes the growth of dark, coarse facial hair.

 

[Father_of_Shiseido]

Lmao, yeah yesterday someone said my skin is starting to look feminine, but if i turn out looking like a girl, then oh well i don't care.

Is that you in your DP?

 

[Yar]

I know your pain man, i started losing mine later than you, at 17 years old, but the stress of balding has taken a toll on my mental health. It became an obsession to get my hair back, i spent a lot of money on doctors who did no help, some "hair specialist" even scammed me for $2,500 and i knew it might be a scam but that's how vulnerable i was because i was desperate. I tried Finasteride which did nothing. I tried Dutasteride which did nothing. i tried topical minoxidil which maintained for a while but eventually did nothing. For the first 3 years i was so stressed out that towards the end when i knew none of those meds were working in my body i would go into full blown psychosis where i would feel panicked with anxiety and have many hallucinations where i would feel like i am having a bad acid trip. It sucked me dry of emotions and i can't feel enjoyment in anything at all no matter what it is, people said get out and travel, so i traveled the world and got no enjoyment out of it, and i think balding has altered my personality in a way that i am bitter inside and i also lost my long time girlfriend because of it (i assume). I live in isolation to this day because of it. i don't go outside or talk to anyone unless i have to. i guess it depends from person to person but balding can literally destroy ones life. HRT is the last hope for myself, i said the same, i choose side effects over depression because i don't want to feel like a piece of sh*t anymore.

And how do you support yourself if you don’t go anywhere? Do you have any work? I always wonder how people live in the United States, propaganda on TV can say what it really isn’t at all! supports the US government? In Russia, no ordinary person provides assistance in the money, you have to work. Many governments of different countries provide financial support to their citizens!