Exploring The Hormonal Route. Hair=life.

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JaneyElizabeth

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nWo Wolfpac said:
So after being on 200 mg spironolactone and 4 to 6 mg estriol for one month I'm a little disappointed. I didn't expect to grow hair back this fast but I did expect my hair loss to be halted, unfortunately I continue to shed and lose hair at my usual rate which really worries me because It's getting to the point where if it gets any worse I'm going to have to shave my head which I really do not want to do. I'm going to stay down this path of course since it is my only option left. I'm going to restart taking finasteride as well at least a few times a week. It did nothing for me before but I'm hoping that in conjunction maybe it will help boost what the spironolactone is trying to do. I know I need to be more patient but damn I just want a sign that it's working just a little peach fuzz is all I ask. I just want some decent regrowth it doesn't have to be a miracle like bridgeburn. I'm so sick of this sh*t. I just wish I knew if this will work or not I'm so tired of worrying about it. f***.
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When you conjecture dosages and then stop, you never get anywhere. Use what works with the least E2 and least of an AA but it might lead to a shed and then you will likely have to keep titrating upwards. There's a reason why HRT isn't a thing for male pattern baldness. It's only now because meds are much easier to get but even in the 70's we knew that estrogen was a dead end if feminization was an issue. No free lunches in life. You are unlikely to discover anything new but you are helping the cohort by trying and printing your protocol so we know what might not work which is just as important or more so than knowing what does work.
 
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nWo Wolfpac said:
No I'm not. I used it for a year 4 or 5 years ago, I think it helped a little but it gave me the dreaded bloated face dark circles under my eyes. Im also convinced it gave me early wrinkles on my forehead because I used to use the liquid and it would always drip down my face.
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Buy some f*****g concealer for under the eyes. $9 on Amazon. People who want to regrow hair can't be picky about eye circles. Get an eye job. Goddess bless but I tire of hearing people use this circles under the eyes scare scenario.
 
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Norwoody

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The quality of Anty's hair is so much better there too. Something finasteride doesn't do anything significant for.
 
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hemingway_the_mercenary said:
really dont get why people are trying to copy this regiment and take all these drugs orally when for alot of them you can take it topically and its just as effective with less systemic side effects

please educate yourselves before going on such aggressive regiments, I see so many noob questions being asked in this thread.

First of all why are people even considering spirinolactone when there are drugs like bicalutamide that are much safer and more effective? Basically every anti androgen is better than spironolactone, if you dont care about side effects may as well use one with less harsh side effects.
Second of all, if a drug does not need to be converted to a metabolite to become active you can use it topically and get all the same effects
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Because topicals either don't work or they barely work and many are trying for pubertal hairlines. It makes no sense to argue against because we aren't interested in avoiding estrogenic effects. You are preaching to yourself and if your way worked, then people would be posting pics.
 
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hemingway_the_mercenary said:
really dont get why people are trying to copy this regiment and take all these drugs orally when for alot of them you can take it topically and its just as effective with less systemic side effects

please educate yourselves before going on such aggressive regiments, I see so many noob questions being asked in this thread.

First of all why are people even considering spirinolactone when there are drugs like bicalutamide that are much safer and more effective? Basically every anti androgen is better than spironolactone, if you dont care about side effects may as well use one with less harsh side effects.
Second of all, if a drug does not need to be converted to a metabolite to become active you can use it topically and get all the same effects
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This is simply not true although people like to say so. Transfeminine Sciences breaks out the risk factors for the various AA's and bica is worse for the liver than spironolactone and CPA is worse than either but they all work about the same for hair loss and feminization.
 
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JaneyElizabeth

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hemingway_the_mercenary said:
how can someone so cocky be so dumb

How many times do I have to tell you, that is only in mutant ARs of cancer cells. You have not even bothered to read the literature on this subject yet you keep spewing this out like diarrhea. Why are they bothering to make new drugs to block the receptors, have you ever stopped to think of that? Its because come cancer cells had mutant ARs that were able to grow or even use the drugs as agonists. You are litterally linking a study on mutant ARs of cancerous prostate cells. Either you didnt bother to read it or do you lack the ability to understand

Thats why they came out with Enza and Daro

Stop repeating this everywhere, you have no clue what youre talking about. So far there have been 3 people on this forum who have tried topical Bica including me and we have all had great results from it in terms of hairloss

Spirinolactone is used more because there is a negative connatation with using a cancer drug as part of hormone therapy. Common sense should have told you that its not a good idea to be on a diuretic for long periods of time, but I guess you dont have that

The whole point of topical estradiol is to use a lower dose than oral while getting a sufficient local dose. And no it doesnt have a longer half life you dummy. Once estradiol goes systemic it is eliminated at the same rate wether its taken orally or topically.
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If I ever submit an answer like this please tell me so I can smack myself.
 
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hemingway_the_mercenary said:
how can someone so cocky be so dumb

How many times do I have to tell you, that is only in mutant ARs of cancer cells. You have not even bothered to read the literature on this subject yet you keep spewing this out like diarrhea. Why are they bothering to make new drugs to block the receptors, have you ever stopped to think of that? Its because come cancer cells had mutant ARs that were able to grow or even use the drugs as agonists. You are litterally linking a study on mutant ARs of cancerous prostate cells. Either you didnt bother to read it or do you lack the ability to understand

Thats why they came out with Enza and Daro

Stop repeating this everywhere, you have no clue what youre talking about. So far there have been 3 people on this forum who have tried topical Bica including me and we have all had great results from it in terms of hairloss

Spirinolactone is used more because there is a negative connatation with using a cancer drug as part of hormone therapy. Common sense should have told you that its not a good idea to be on a diuretic for long periods of time, but I guess you dont have that

The whole point of topical estradiol is to use a lower dose than oral while getting a sufficient local dose. And no it doesnt have a longer half life you dummy. Once estradiol goes systemic it is eliminated at the same rate wether its taken orally or topically.
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3 people who might be on the thread but who aren't posting except for Ein
hemingway_the_mercenary said:
how can someone so cocky be so dumb

How many times do I have to tell you, that is only in mutant ARs of cancer cells. You have not even bothered to read the literature on this subject yet you keep spewing this out like diarrhea. Why are they bothering to make new drugs to block the receptors, have you ever stopped to think of that? Its because come cancer cells had mutant ARs that were able to grow or even use the drugs as agonists. You are litterally linking a study on mutant ARs of cancerous prostate cells. Either you didnt bother to read it or do you lack the ability to understand

Thats why they came out with Enza and Daro

Stop repeating this everywhere, you have no clue what youre talking about. So far there have been 3 people on this forum who have tried topical Bica including me and we have all had great results from it in terms of hairloss

Spirinolactone is used more because there is a negative connatation with using a cancer drug as part of hormone therapy. Common sense should have told you that its not a good idea to be on a diuretic for long periods of time, but I guess you dont have that

The whole point of topical estradiol is to use a lower dose than oral while getting a sufficient local dose. And no it doesnt have a longer half life you dummy. Once estradiol goes systemic it is eliminated at the same rate wether its taken orally or topically.
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how can someone so cocky be so dumb?

You tell us.
 
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Norwoody

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Just a random thought: if finasteride worked for most people then there wouldn't be terms like "good responder". Seems like it's a rarity really.
 
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JaneyElizabeth

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Ein said:
Sorry to barge in, but I am a bicalutamide user and I think it has worked great on me. I can send you the pics now, but I don't have the before pics. There's a thread of mine on these forums and I did upload a few pictures there, but that was when I had already started bicalutamide.
Sorry I don't have any proofs like Bridgeburn collected, because I delete the photos that show my hair loss, since I don't want to feel more depressed about it than I already am.
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We get that about the psychic harm as neither Bridge nor I particular like close ups of our temples as they respond more slowly but they do respond (or I am crazy and all of my six years of pics are fabricateded) but for many reasons, assertions without pics over large periods of time are not particularly useful. If you go to trans sites, people and researchers in the field cannot agree on much of this. Assertions by one or two or six people particularly without pics or posting your results from testing as I have, are not very useful but your story is encouraging. It's just not science and I could pull 10 different articles that say something different. MtF's don't know what grows hair or breasts that's why I advocate for people simply copying protocols or titrating upwards to them and shedding might be unavoidable for many regardless of what they use.

Goddess Bless
 
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JaneyElizabeth

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Gergely said:
Maybe it's not the best idea to reply to messages posted 3 years ago
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I am trying to avoid copying and having to comment but I can move it to my thread. Many of these folks are still active. But now without Bridge as our authority, noobies just say or believe whatever and they haven't read the thread. Still very few people are posting pics which disappoints me but I do get it. Maybe this just works for a few of us. It's easy to trick oneself. There's a ton of value in this thread but there's so much dross that it's hard to get to the juicy parts. Maybe I will try to do an outline of everything Bridge says to post because dude's exceptional as an expert on all of this, anecdotally, pic-wise, and in terms of charm and dignity.
 
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JaneyElizabeth

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Ein said:
There's a reason why I don't post my pics here. I know it shatters self confidence of a lot of balding men.
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I do agree with this. I've started posting much less because it feels like bragging when others aren't progressing but you and I are chemically female.
 
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JaneyElizabeth

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Marky said:
Needless to say your skin looks paler. Are you finding more freckles on the skin?
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Paleness is an all but universal side effect in all races from MtF HRT. The skin itself repairs itself so of course we all look younger. HRT is more about rejuvenation than growing crappy rogaine hair or whatever. Female hair is virtually always nicer than male hair but particularly in whites and Semites.

That's why it is important to emphasize the scalp flora and skin environment differences. So just dunking one's head in topicals is not a complete solution for folks who want a full head of hair with loooong anagen phases that permit growth of long hair like Bridge's.
 
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