Exploring The Hormonal Route. Hair=life.

Almas

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Just wondering. Some have reported much less sebum on dutasteride since it blocks the type I enzyme. I've never heard of someone getting on finasteride and reporting reduced sebum.

You probably are a poor aromatizer like myself. Good to get tested for sure though.
I think testing will not tell a lot, because the sensitivity to E can also be different
Perhaps now my E is just rising and will peak in a month. I still have acne so androgens are still working
 

Ticken

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Holy, thats much! With only 2mg... and bica.

Ikarus's estradiol level of 719 pmol/L converts to 195 pg/ml. (pg/ml is the unit of measurement that is mostly used in US and in clinical studies)
I've read accounts of male hair growth that was kickstarted with E2 levels of 90-100pg/ml.
The male reference range for estradiol is 10-60 pg/ml just for perspective. EDIT: ref range for estradiol is 10-40 pg/ml
There's a basic conversion calculator for E2 here:
 
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Almas

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Ikarus's estradiol level of 719 pmol/L converts to 195 pg/ml. (pg/ml is the unit of measurement that is mostly used in US and in clinical studies)
I've read accounts of male hair growth that was kickstarted with E2 levels of 90-100pg/ml.
The male reference range for estradiol is 10-60 pg/ml just for perspective.
There's a basic calculator for E2 here:
So, for guaranteed regrowth, my E must be at the level of 90-100? Does it give significant feminization? Bica raises E to 30-45pg / ml, according to the charts on the internet. A dose of 150 mg increases E by 1.5-2.5 times.
 

Gergely

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So, for guaranteed regrowth, my E must be at the level of 90-100? Does it give significant feminization? Bica raises E to 30-45pg / ml, according to the charts on the internet. A dose of 150 mg increases E by 1.5-2.5 times.
What's the point of increasing your estrogen by overdosing on bica? Do you think it will be less "feminizing"? Because it won't be
High amount of estrogen in your body will act the same no matter if it's from bica or e2 pills
 

Gergely

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What's the point of increasing your estrogen by overdosing on bica? Do you think it will be less "feminizing"? Because it won't be
High amount of estrogen in your body will act the same no matter if it's from bica or e2 pills
You will have no protection against any of the feminizing effects that you are meticulously trying to avoid
 

Pls_NW-1

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What's the point of increasing your estrogen by overdosing on bica? Do you think it will be less "feminizing"? Because it won't be
High amount of estrogen in your body will act the same no matter if it's from bica or e2 pills
Yeah, and because of that I see no reason taking high E, maybe E not at all, because Bica gives you already the E you need...

Am I right!?
 

Gergely

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Yeah, and because of that I see no reason taking high E, maybe E not at all, because Bica gives you already the E you need...

Am I right!?
It might give you sufficient amount to regrow hair it might not, but if you have to take 150mg to do so. Than just use e2 imo.
Also if you don't reach female levels of estrogen while in an androgen deprived state you'll increse your chances of
bone mineral density loss and fractures, coronary heart disease, deep vein thrombosis and diabetes.
 

JaneyElizabeth

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Yup, same. I stopped yesterday. Shedding was out of control
See the owner of the site's article on shedding which is excellent. The difficulty with marginal treatments is that they might increase shedding while at the same time being overrun by virulent male pattern baldness hair loss making such treatments not recommended for most people. I think Biestro is probably better as maintenance and for females unless you use lots and lots. MtF's have no choice really but to strap themselves in and ride out the shed since there are better pastures ahead but for guys, these treatments might make things worse. This is why I think starting with Min two percent is recommended over five percent and then one can titrate upwards if no shed or significant shed appears.
 
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JaneyElizabeth

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Yeah, and because of that I see no reason taking high E, maybe E not at all, because Bica gives you already the E you need...

Am I right!?
No. You misinterpreted what he is saying, I believe. We/he are saying that Bica, if it works, is simply another form of high estradiol dosing that is perhaps not high enough to cause significant regrowth but maybe it is, but you won't avoid major sides and most MtF's even in an XY context experience far more sides from bica and spironolactone than from estradiol and perhaps more so than CPA and MPA which actually do reduce T without f*****g with receptor sites.
 

Norwoody

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So, for guaranteed regrowth, my E must be at the level of 90-100? Does it give significant feminization? Bica raises E to 30-45pg / ml, according to the charts on the internet. A dose of 150 mg increases E by 1.5-2.5 times.
Bluecyclone has never done estrogen and was recently tested in the 80s
 

JaneyElizabeth

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I wonder if it is possible to regrow on E+AAs and continue with AA's (Bica+duta/fina)...

In theory it should work
That might work. Theoretically, if the fibrosis theory of baldness is correct, it should at least work for a while. You need to maintain anagen so it might work better than duta but duta doesn't interfere with sexual prowess or fertility.
 

DogoDiLaurentiis

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Yes, that's right. But if we talk about guaranteed treatment, then it's more about estradiol. However, I will have to monitor the E and T levels and get tested. It's more troublesome

I am currently taking 50mg. My skin produces less oil, but it's still not dry, closer to oily. This probably suggests that androgens continue to work.

This is pretty much concurrent with my experience, if your body easily converts test to E, you probably need to rely mostly on androgen inhibition and blocking to a degree, whatever that is, finasteride, dutasteride, bica, cypro, etc. If not, as it seems to be in my case somewhat, you need to supply exogenous estrogen to fill the gap.
 

Gergely

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All i'm saying is don't use 150 mg bica to increase e2, instead use 50mg and 1mg e2 swallowed. For you own good.
 

JaneyElizabeth

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Safer than what? It's not safer than estogen and it's not safer than spironolactone. It probably has fewer or far fewer daily sides than spironolactone but in the long-run, the two appear to be equally safe for liver, etc. In terms of sides and efficacy as per Dogo, yes we all differ in how we process hormones.
 

Gergely

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Safer than what? It's not safer than estogen and it's not safer than spironolactone. It probably has fewer or far fewer daily sides than spironolactone but in the long-run, the two appear to be equally safe for liver, etc. In terms of sides and efficacy as per Dogo, yes we all differ in how we process hormones.
Bica is a selective nonsteroidal antiandrogen, while spironolactone is potassium sparing diuretic, and a weak steroidal antiandrogen. Bica is infinitly better and is not harmful for the liver contrary to popular belief.
 
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