Exploring The Hormonal Route. Hair=life.

[Pls_NW-1]

I am not certain that person suffers from male pattern baldness.

No he doesn't. Its not the common male pattern baldness. But its androgen driven.

 

[Gergely]

what more can I do in your opinion? I'm going to take an anti-dandruff shampoo but I have tried everything, all the remedies and nothing works I'm cursed

You can try fluridil if nothing works, apparently is a good topical NSAA

 

[DogoDiLaurentiis]

I agree. There's definitely people out there with low T, low E, and/or other issues that those drugs don't address. It does irk me that people are still stuck in that mentality of "the big 3 is the first line of defense". Generally it will help but that doesn't make it the optimal first line for every individual.

I think minoxidil is a good way to differentially figure out if there's "something else" going on, because of the way minoxidil works, it doesn't just "force" your hair to grow, it increases expression of PGE2 and adenosine which induces hair growth, in some more unusual cases of hair loss this can be something the body is faltering on without outside intervention.

For example if there is too much PGD2, and it is adversely impacting hair growth, which means you need more than just minoxidil but a way to actively curtail PGD2 expression.

 

[DogoDiLaurentiis]

what more can I do in your opinion? I'm going to take an anti-dandruff shampoo but I have tried everything, all the remedies and nothing works I'm cursed

You're not describing anything outside of hairloss, you need to describe what is happening with your skin, and specifically your scalp if anything is happening.

I can't help if I don't know if there's anything else going on outside of just hair fall.

 

[DogoDiLaurentiis]

I'll throw some things out there for you.

if

- you have scalp acne

-oily scalp

-irritated scalp

-hair loss

and

You have used nizoral for two months with no improvement

You have taken antibiotics with no improvement

You have taken oral and/or topical antifungals with no improvement

You have used topical corticosteroids with no improvement

You need to go to a dermatologist and ask them about demodex skin parasite infestation.

I have had this, it is a common ocurrence and in many people it does not cause problems but sometimes in some people it can, we all have bacteria and microorganisms living on our skin, but sometimes they get out of control.

Demodex can absolutely cause inflammatory hair loss and many conventional remedies don't work for it, you need to use topical or oral ivermectin to fix the problem if it is.

Demodex is what causes mange in dogs but humans can get it, it can cause their eyebrows and eyelashes to become infected and fall out. It is often mistaken in people for just having acne and oily skin unless it is affecting your eyelashes because very few conditions do that, but basically demodex can get into your pores and follicles and cause problems, even in places where you don't have any hair, such as your nose. One of the adverse reactions your body has to it is that it starts creating sebum in excess which causes inflammation and acne on top of what the parasite is doing.

Unless you give me more info I don't know what I can do to help you.

 

[Gergely]

I agree. There's definitely people out there with low T, low E, and/or other issues that those drugs don't address. It does irk me that people are still stuck in that mentality of "the big 3 is the first line of defense". Generally it will help but that doesn't make it the optimal first line for every individual.

Lets put CPA and E2 in the public water supply for everyone's sake

 

[JaneyElizabeth]

You are very lucky to have recovered so much hair, we are both young I understand why you have made such a big diet to recover your hair, I wrote a post on my hair loss that eats my life

Lol. I am old so you must be referring to Gergely!

 

[JaneyElizabeth]

You can try fluridil if nothing works, apparently is a good topical NSAA

And even using anything that isn't a complete fraud can lead to improvement for a time due to placebo effects....

 

[JaneyElizabeth]

I understand what you are saying, you should know that I was taken aback by the fact that I was losing a lot of eyelashes or also smiled.

How do I know if I have scalp inflammation? I get itchy a few times, I don't know what else to say as a sorry indication ..

I think hair loss is for males, virtually always accompanied by inflammation. Treatments can relieve or initially perhaps worsen inflammation which is probably why so many of us recall itching of scalp that makes it difficult for us to stop fingering our hair. I had dermatitis sores that were productive on my scalp covered by hair but not in the balding areas, which I had to periodically pick off as they caught the tooth of the comb and were painful. All gone now.

 

[Gergely]

And even using anything that isn't a complete fraud can lead to improvement for a time due to placebo effects....

idk what you're referring to i'm not a fluridil expert

 

[Depression]

I understand what you are saying, I'm not sure how to tell if I have scalp inflammation.

I get itchy a few times and also some time ago I was taken aback by the amount of eyelashes or eyebrows I was losing.

Sorry for not giving more information I don't know what to say

 

[Gergely]

I understand what you are saying, I'm not sure how to tell if I have scalp inflammation.

I get itchy a few times and also some time ago I was taken aback by the amount of eyelashes or eyebrows I was losing.

Sorry for not giving more information I don't know what to say

Losing eyebrow hairs sounds like a thyroid problem. You should opt in for a blood test.

 

[JaneyElizabeth]

idk what you're referring to i'm not a fluridil expert

Many early studies with min had the control group using purified water or alcohol and some of them had an improvement in hair counts. This has nothing to do with fluridil or CB specifically but indicates the power of suggestion. All of the experimental guys on here are engaging in self-observation and self assertion of improvement which is anecdotal and highly disfavored under standard statistical and scientific methodology. When you add in the complete absence of pictorial support, the experimental guys, at least on here, are not using scientific method as preferred in terms of implementation.

Another thing is that the mere application of alcohol or water when rubbed/massaged in twice daily might improve hair counts due to mechanical increases in blood flow.

Having said that, anecdotal recounts are sometimes all that we have and they clearly have their place although far overused on here. Even with pics, we have differences in hair length, lighting, styling, amount of dampness, hair spray, etc. Hopefully no one is using concealers except to show how well they work on their own with respect to miniaturized hair.

One reason why I advocate for standardized protocols that we at least know worked for somebody, is that it makes some of the non-scientific aspects take on less significance so instead of saying 12 people saw all but complete restoration using HRT, instead we can say that of the 12, nine were using exactly the same aggressive HRT protocol.

 

[Gergely]

Many early studies with min had the control group using purified water or alcohol and some of them had an improvement in hair counts. This has nothing to do with fluridil or CB specifically but indicates the power of suggestion. All of the experimental guys on here are engaging in self-observation and self assertion of improvement which is anecdotal and highly disfavored under standard statistical and scientific methodology. When you add in the complete absence of pictorial support, the experimental guys, at least on here, are not using scientific method as preferred in terms of implementation.

Another thing is that the mere application of alcohol or water when rubbed/massaged in twice daily might improve hair counts due to mechanical increases in blood flow.

Having said that, anecdotal recounts are sometimes all that we have and they clearly have their place although far overused on here. Even with pics, we have differences in hair length, lighting, styling, amount of dampness, hair spray, etc. Hopefully no one is using concealers except to show how well they work on their own with respect to miniaturized hair.

Excuse my bluntness, but this observation has questionable relevance to anything we discussed earlier. i don't depend on what people believe is the best, the only thing that matters to me is getting a hold of my androgens.

 

[JaneyElizabeth]

Excuse my bluntness, but this observation has questionable relevance to anything we discussed earlier. i don't depend on what people believe is the best, the only thing that matter to me is getting a hold of my androgens.

You asked about fluridil which I believe works some but for some people, it obviously is going to work better than for others. In scientifically set-up testing everything is the same as much as possible:
amounts, application methods, hair length, lighting conditions and with respect to whether people know or not if they are using the purported active ingredient.

Placebo effects can be quite strong and perhaps for many/most polysorbates worked at least partially via the placebo effect. This has nothing to do with AA's in general except that virtually none of us are using them under the same circumstances as would be true in a scientific setting or in the same scalp environment and with the same adjunct treatments which lowers my ability or yours to make blanket statements except it worked for us, given our entire protocol. With the stacks that some of us are using, at best I can make generalized statements about what works for me, age included, and what works for others and it makes it difficult for us to make suggestions for others as opposed to a person using only estradiol, which excepting mechanical treatments, should in my view, as long as targets are met, work better than anyone's huge stack but again, there are some treatments that are purported to "improve" more so than increase it's volume weight and coverage.

When some experimental guys are using 20 different treatments that alter hormonal levels and scalp environment, they might be using 12 things that work, at least non-synergystically, in an additive fashion as opposed to 12 things that work and eight that actually hinder progress. None of these guys can keep track of so many things and often huge stacks resemble rooster mentality of crowing about "look how smart I am, I know about 16 different prostaglandins that you aren't using...."

There's very little scientific about it without testing using all 20 ingredients or at least being able to separate out marginal treatments. This is why I rarely frequent experimental threads. It's a Rube Goldberg hair loss approach with flow charts and stuff that "should work" but rarely does or works so poorly and often at exorbitant cost that it's not even close to worth it for mortals who just want regrowth. HRT works sensationally for some/many people; oral min might also, with finasteride/min/keto also less so; the rest are not pertinent to 99 percent of us.

 

[Gergely]

You asked about fluridil which I believe works some but for some people, it obviously is going to work better than for others. In scientifically set-up testing everything is the same as much as possible:
amounts, application methods, hair length, lighting conditions and with respect to whether people know or not if they are using the purported active ingredient. Placebo effects can be quite strong and perhaps for many/most polysorbates worked at least partially via the placebo effect. This has nothing to do with AA's in general except that virtually none of us are using them under the same circumstances as would be true in a scientific setting....

Well okay, someone who's presumably poisoned might suffer from placebo but ultimately unlikely to die. But the ones actually poisoned will die.

 

[Murkey Thumb]

I used bi-est for about a month, and straight estriol for a month prior, I would say nothing even comes close to what I'm experiencing with straight 17b estradiol, nothing else.

Estriol made my skin nice, and stabilized my hair but did not induce intense regrowth and and a marked improvement in scalp and hair texture the way estradiol has.

However that being said a shed is indicative of starting a new growth cycle, however with estrogen that should basically stop after a point and new growth should come in strongly afterward.

I don't know what keto is whether you're mentioning ketorolac, but I do also use anti-inflammatories, but I use them sparingly as using them constantly deprives your body of the good inflammation necessary to induce hair growth.

If you're getting the dreaded breast area tingling indicative of gyno, what you need to do is start taking magnesium, as it increases excretion of estrogen from your body. This is something I did not learn until very recently and was probably in some way contributing to my reduced natural estrogen over the years.

Also, beta sitosterol will inhibit aromatase which might seem like that's counterintuitive, but what you want is the beneficial effects of site application of estrogen without it overloading you in vivo.

Also consider using betamethasone topical if you have any scalp inflammation as it increases estrogen receptor sensitivity meaning you will require less circulating estrogen to do it's job at the hair follicle receptor level.

Thanks I will definitely give the magnesium a go and also betamethasone. Where do you get the 17b from?

 

[JaneyElizabeth]

Well okay, someone who's presumably poisoned might suffer from placebo but ultimately unlikely to die. But the ones actually poisoned will die.

Yes but we don't use poisons or excessively toxic substances usually except for cancer research. If scientific testing indicates that something unabashedly works or is toxic beyond benefit for a save few, they stop testing immediately or alter the protocol.

 

[DogoDiLaurentiis]

Thanks I will definitely give the magnesium a go and also betamethasone. Where do you get the 17b from?

HRT.cafe, you'll have to find out a supplier that sends to your country.

 

[DogoDiLaurentiis]

I understand what you are saying, I'm not sure how to tell if I have scalp inflammation.

I get itchy a few times and also some time ago I was taken aback by the amount of eyelashes or eyebrows I was losing.

Sorry for not giving more information I don't know what to say

Itchy scalp is a sign that something else is going on, or worse yet, pain, pain that you cannot ignore is a sign you need to get something treated.