AFAIK there haven't been any studies about this however if it truly generates new hair follicles it should. It's possible fibrosis could reduce the effects but even then microneedling reduces fibrosis...
Follica Microneedling Protocol Patent Disclosed
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Chromeo
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He stopped all of his regime (finasteride, minoxidil, dermarolling) so of course all gains will be lost. For a start, any hairs regrown on the top of the head by dermarolling are still susceptible to the negative effects of DHT, so without finasteride they will miniaturise the same way they did before. They are not DHT-resistant hairs like those from the donor area.
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Lol, that's saying nothing whether it will take a few months after stopping, or if it will take 20-30 years like his original hair.
Damn that follica finished phase 2 in December 2019.They take this thing too damn slow
Chromeo
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It's pretty clear from his documentation that they are lost quickly. He's been off his regime for 4 months and he appears to have lost a considerable amount of ground already.
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For the record, Dr. Cotsarelis mentioned at a Follica conf years ago that its not a silver bullet treatment, Finasteride will still be required to maintain and avoid DHT damage
Another curious fact, let's say you've been 20 years on Finasteride and have been capable of maintaining a NW2-3 pattern, avoiding a complete horseshoe NW7 pattern this long time.
If you stop Finasteride, you'll be back at your "pre-programmed" final pattern (NW7 for heavy balders) in a matter of months, the kickback is hard and fast
Another curious fact, let's say you've been 20 years on Finasteride and have been capable of maintaining a NW2-3 pattern, avoiding a complete horseshoe NW7 pattern this long time.
If you stop Finasteride, you'll be back at your "pre-programmed" final pattern (NW7 for heavy balders) in a matter of months, the kickback is hard and fast
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Either way you’d have to be a f*****g lunitic to stop.
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Good point. We might be able to maintain microneedling using duta/finasteride or other prostate medications. What might happen also is that many/most derma-rollers are operating in an environment of higher levels of DHT as a baseline and so then, when one stops, it's like whoosh in comes the DHT and I think I have seen people noting complete fall-out after desisting from microneedling for 30 to 180 days.
I think Twist1 is constitutively active in bald scalp and this acts as a brake on Wnt signaling and the growth phase of the hair follicle. Microneedling increases Wnt ligands while minoxidil inhibits GSK3b(Wnt inhibitor) and this counteracts Twist1's suppression of Wnt signaling, but Twist1 is still there, and when you remove microneedling and minoxidil the balding process happens again swiftly due to the constitutively nuclear Twist1 combined with your cells already having reached an age where they are more easily stressed. It's similar to how when older eunuchs are given testosterone their hair falls out more quickly than younger eunuchs, only this is much worse because you already have high Twist1 expression. I believe PRLR antagonism reverses the cause of constitutive Twist1, and that's why results from HMI-115 last much longer after discontinuing treatment than the results from minoxidil and microneedling.
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But much longer anagen might trump the importance of DHT somewhat and a lot of the analysis ends up being circular in terms of cause and effect and which is which.
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Also, microneedling can heal really bad scarring very, very well. It seems to have youth and healing effects on all tissue and I am willing to bet that shrink donor area scarring and also cobblestone or baby doll hairline scarring. Grafts that had given up the ghost now appear to all lie flush and are productive of excellent hair not the eh hair from transplants for diffuse thinners like me. I do it weekly on ever single cm of my body above the ahem, tits. Yes, I tried rolling them too but the pain was too great to do it much there.
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Hello ... I wrote to you in private ... I hope not to disturb thanks
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@pegasus2 $56M should do it…
Hope Medicine HMI-115: Phase 1 Trial Success and Phase 2 Recruitment | Hair Loss Cure 2020
Hope Medicine (HopeMed) of China received $56 million in Series B financing from Qiming Venture Partners and Grand Flight Investment. CEO Henri Doods interview.
www.hairlosscure2020.com
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No we do not.
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Sweet innocence, believing a roller gonna save his fullhead
No it won't, there's nothing stronger than DHT dmg, and it's get worse as you age, your androgen sensivity will increase thus your hairloss with it
A roller by itself won't be enough (if you really have Androgenetic Alopecia and not a mature hairline with a huge BDD problem of course)
There's a few who magically self stabilize before reaching NW7, don't know why exactly, like if final Norwood pattern was written in your gene pool somewhere, but don't hope solely on that
Big 3 (and Dermaroll for a sweet enhance effect, minoxidil absorption, fibroblasts stimulation) is still all we got, and for some, even those synergic treatments are not enough to maintain despite a continuous usage, so what do you expect as a answer ? All those treatments are for LIFE son, welcome to hell
NO as a definitive answer, proof is life, people out there who still balding, and history of mankind, and most likely the fact that we hear about dermaroller for like 20 years now, if only this was so easy
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LOL... love it.
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aren't you on the wrong thread then? this thread is about MICRONEEDLING.
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Nothing.
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not necessarily. Follica released their Microneedling protocol. that's what this thread is about. if you're looking for a hair loss cure... well.... another 15 years?