Follica Microneedling Protocol Patent Disclosed

[John Difool]

I read the articles but I need a CAS no or a reference on Alibibi

 

[John Difool]

Yes, so that stuff is not cheap either. I think baring all the stuff I will put on my cranium and ingest this year, I'll be reaching $50K annum spending

 

[John Difool]

How does one get Valproic acid? That stuff is supposed to trigger neogenesis after needling

 

[Xander94]

It just takes too long. Screw it, I'm ordering an SHH agonist. Nobody in my family has had cancer, and my genetic profile shows a reduced risk of cancer so I figure the risk is minimal.

good luck, hair is everything, I am doing hair transplant soon to replace my wispy hair

 

[John Difool]

good luck, hair is everything, I am doing hair transplant soon to replace my wispy hair

Then you are posting on the wrong forum. There is a dedicated one for people like you who believe that displacing hair from the back of their head to the front will solve their issue. Not going to ague with you, if this is YOUR solution to your own problem, but that's not interesting to read in this thread.

 

[Nsas]

for those who are following the Follica protocol, are you also doing daily microneedling for absorption and at what depth? i feel like as long as the depth is low, maybe 0.5, microneedling for absorption will still be a good addition.

 

[John Difool]

for those who are following the Follica protocol, are you also doing daily microneedling for absorption and at what depth? i feel like as long as the depth is low, maybe 0.5, microneedling for absorption will still be a good addition.

I never groked the daily absorption motivation. < 500 daltons will be absorbed by the scalp. Not need to perforate more. In fact microneedling on top of the Follica protocol may cause more harm than good. The skin needs to heal and become healthy again to grow hair. So why torturing it more with daily perforation?

 

[John Difool]

I think they are skipping minoxidil on the microneedling day just to be safe about it. In fact, if they supported the absorption path they would ask to use minoxidil the day one is microneedling. My point is not about better absorption when microneedling but the fact that the skin needs to heal at some point to trigger regrowth. The protocol doesn't state you need to microneedle everyday. If fact, it says every two weeks. So what is the point of following their protocol if you are in fact microneedling every day just for better absorption?

 

[John Difool]

Sure, that may or may not work. I take oral minoxidil so I don't have to worry about absorption every darn day that way.

 

[kiwi666]

Sure, that may or may not work. I take oral minoxidil so I don't have to worry about absorption every darn day that way.

I’m also on OM. How many MG’s? Any sides?

In terms of the daily needling. Have you read about Chen and his results.

I know there is hard science backing up giving time to heal. But there is no known science on light needling and whether that interferes with the healing process.

 

[John Difool]

Oral minoxidil 10mg splitted twice daily morning and night time.

Where can I read about Chen's results?

The light microneedling is where I am confused about. 0.75mm depth is already light, so what do we call lighter, less surface, less holes per cm2?

EDIT: I guess this is the study?

https://www.ncbi.nlm.nih.gov/pubmed/29028377

Nothing really new here. every fortnightly and minoxidil + microneedling is better than either. What else am I missing?

 

[kiwi666]

Oral minoxidil 10mg splitted twice daily morning and night time.

Where can I read about Chen's results?

The light microneedling is where I am confused about. 0.75mm depth is already light, so what do we call lighter, less surface, less holes per cm2?

EDIT: I guess this is the study?

https://www.ncbi.nlm.nih.gov/pubmed/29028377

Nothing really new here. every fortnightly and minoxidil + microneedling is better than either. What else am I missing?

Chen’s just a member who’s had good results on daily 1mm.

I think you’re right about the light wounding at 0.75, so in this instance it’s to do with the holes per cm2 causing effectively a burn like result.

Thats how people describe it anyway. Turns out this might be enough to trigger the healing process accordingly.

 

[kiwi666]

Well, I am only able to get SAG hydrochloride at the moment, so it looks like I'm going with purmorphamine instead.

Sorry, I missed that... how do you use purmorphamine / whats the relationship with this protocol?

 

[pegasus2]

Sorry, I missed that... how do you use purmorphamine / whats the relationship with this protocol?

SHH agonist. SHH-GLI signalling is required for hair follicle neogenesis.
https://www.nature.com/articles/s41467-018-07142-9

As far as I know I'm the first person to ever try purmorphamine on the forums. 4 people tried SAG on the private forum, but I don't think they did it in conjunction with wounding. It's a dangerous pathway.

 

[Throwaway94]

SHH agonist. SHH-GLI signalling is required for hair follicle neogenesis.
https://www.nature.com/articles/s41467-018-07142-9

As far as I know I'm the first person to ever try purmorphamine on the forums. 4 people tried SAG on the private forum, but I don't think they did it in conjunction with wounding. It's a dangerous pathway.

You're a f*****g pioneer. Out of curiosity, any reports of success from those 4 people that tried it without wounding?

 

[John Difool]

Free base is cheaper but it's also unstable so I didn't buy it. I got SAG HHG stable and that's expensive.

 

[John Difool]

I'll stick to low dose and weekly and see what happens. I was quoted on Alibaba and free base version was cheaper because it's unstable.

 

[John Difool]

This is how much dead skin I peel off my scalp after doing this protocol. This wasn't even all of it. I scraped off 2 big chunks that had 5 to 10 hairs each in them.

Same here. I massage my scalp and see flakes falling off. Mine are pink because I use SM.

 

[John Difool]

Free base is more expensive. HCL is over 500 daltons, but does dissolve in water. Somewhat less potency with the salt version. You need to use DMSO to increase absorption for either one probably. Dosing is very important as too much turns it into a shh inhibitor. After further thought it probably doesn't matter which one you use. You only need to use it once a week after needling so either one will get through the stratum corneum. I wish I could get a better idea of what dose to use with purmorphamine as that's a lot cheaper and nearly as effective. The 2005 mouse trial should convert to around .05% SAG for humans. I don't know what you mean by SAG HHG? Oh well, if this goes as I hope I might not even need to order more. I have a feeling estradiol works so well by activating shh. This should be superior to estradiol if the dosing is right.

I hope you have read up on the potential for cancer with activating shh. How much are you planning on using? Are you going to use it daily?

Estradiol activating Shh? That's interesting because people on this forum are still wondering if E2 is helping with hair growth. How much are you taking daily and what type?

 

[John Difool]

I finally got some epilim (sodium valproate) 500mg. I crush a pill a day and dissolve it in 90% ethanol alcohol.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192236/

Valproate is a common drug used by various specialties. It is reported to be associated with hair loss upon oral administration which is a cosmetic problem, and on the other hand, topical valproate applications are showing initial evidence to promote hair regeneration.