squeegee
Banned
- Reaction score
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Jacob said:Swanson now has the Setria: http://www.swansonvitamins.com/SWU704/ItemDetail
Acetyl-glutathione next? unk:
Really cheap also Jacob!! unk: unk:
Jacob said:Swanson now has the Setria: http://www.swansonvitamins.com/SWU704/ItemDetail
Acetyl-glutathione next? unk:
rwhairlosstalk said:Hi I see this thread is long, is the glut really working for anyone??? Please God say it is sigh.
squeegee said:What about topical PQQ in a liposomal cream? That would be a good idea I guess.. still don't know if I want to pull the trigger on this: http://www.protect100.com/
IsoShieldâ„¢ Ingredients:
L-Glutathione (reduced)
Ascorbyl Palmitate
L-Methionine
Selenium
Hyaluronic Acid
Catalase
B6 P5P
Superoxide Dismutase
B12 as Methylcobalamin
Alpha Lipoic Acid
Zinc Gluconate
rwhairlosstalk said:Okay so has anyone had any success with this stuff???
Perhaps the most intriguing and cost effective method that I have been using in recent months is a product called "acetyl-glutathione".
Acetyl-glutathione is a compound that actually occurs normally in a human body. It is an analog to the more potent antioxidant, reduced glutathione (the type used intravenously). Reduced glutathione is acted upon by "peptidase" enzymes almost immediately in the blood and tissues, and thus it loses its ability to enter cells and act intracellularly. This happens in a very short period of time and thus IV glutathione, while having a remarkable impact on metabolism, is relatively short-lived. (Inhalation of glutathione, as mentioned above, has shown promise in chronic lung diseases and it is believed that inhalation GSH treatment along with oral acetyl-glutathione supplementation appears to work much better than inhalation alone.)
Acetyl-glutathione has a major advantage over other forms of GSH supplementation. At the tissue level it is very easily assimilated intracellularly and then allowed to perform its powerful antioxidant and metabolic regulatory effects without prior decomposition by peptidases. It has been found that acetyl-glutathione is absorbed orally and is transported to all tissues of the body with remarkable anti-aging effects, anti-viral effects and in some studies an effect on some cancers.
Oral Glutathione
Ingesting direct Glutathione does not raise Glutathione levels since it is poorly absorbed through the digestive system. The fragile tripeptide (3-amino acid) structure of Glutathione makes surviving the digestive tract a near impossibility. Additionally, your cells must generate their own Glutathione to be effective.
Reduced Glutathione
Glutathione must breakdown to its reduced form to work properly within the cells. But introducing the reduced form directly to the body is much like taking oral Glutathione – the effectiveness is lost. Supplementation with reduced Glutathione does not raise tissue levels of this critical antioxidant. Reduced Glutathione is also expensive and not metabolically active. Many doctors report that the clinical benefits achieved with intravenous reduced glutathione are not reproduced when it is taken orally.
Cysteine or L-Cysteine
Glutathione is a tripeptide (3-amino acid) comprised of Cysteine, Glutamic Acid and Glycine. Consuming these three amino acids independently does not ensure Glutathione production and can actually be harmful. Cysteine is the precursor to Glutathione and extremely important to Glutathione production, yet taking Cysteine is ineffective since it is potentially toxic. Cysteine is spontaneously oxidized in the gastrointestinal tract and the bloodstream and cannot reach the cells. Cysteine that does make it into the bloodstream can be further oxidized and do more damage than good. Cysteine may be one of the building blocks f Glutathione, but alone has a negligible impact on raising Glutathione levels.
N-Acetyl-Cysteine (NAC)
N-Acetyl Cysteine (NAC) is a synthetic version of Cysteine that is rapidly converted to the amino acid Cysteine. NAC supplements are moderately effective, but dosing is limited due to the toxic side effects (such as headaches, dizziness, blurred vision) associated with Cysteine Supplementation. NAC decreases Zinc, so supplementing with additional zinc and copper is recommended along with Vitamin C to prevent the Cysteine from converting to Cysteine, which can form kidney and bladder stones.
Recent Study on NAC:
According to recent research at The University of Virginia, N-Acetyl-Cysteine forms a red blood cell derived molecule that makes blood vessels think they are not getting enough oxygen. This leads to pulmonary arterial hypertension (PAH), a serious condition characterized by high blood pressure in the arteries that carry blood to the lungs. The results appeared in the September 2009 issue of the Journal of Clinical Investigation.
Normal hair grows in cycles. Anagen is the active growing phase, catagen is a brief phase when growth slows down, and telogen is a resting dormant phase, where hair falls out, hopefully to be replaced in the next anagen phase. Research shows a positive correlation between GSH content and the percentage of anagen hairs present in a scalp sample, concluding that glutathione helps maintain the hair growth cycle. Researchers theorize that free radical formation plays a role in male pattern baldness. It is possible to measure the breakdown products of oxidative stress in bald and hairy areas of the scalp. The values are doubled in the balding areas. And correspondingly, hairy areas have almost three times as much glutathione.
In male-pattern baldness, androgens (male hormones) target hair follicles, which convert them into even stronger hormones. The unfortunate result is that hair growth slows or stops. M.E. Sawaya at the University of Miami showed that the conversion of these hormones can be influenced by glutathione, suggesting that GSH plays a protective role.
Age-related GSH losses in human hair follicles is part of the total body glutathione depletion described in chapter 6 on aging. Working at the L'Oreal research lab, M. Kermici measured follicular GSH activity in men and women ranging in age from 19 to 102 years and found a significant decline up until about age seventy, then a slower second decline.