I'm actually wondering if these antifungals are potentiating hairgrowth as smo antagonists and subsequent hedgehog agonists through inhibition of the hedgehog (Wnt signaling) pathways. The reduction sterol sythesis might be helping reduce any requirements requirements for Shh signal transcription. Based on a recent study and this suggested association, could itraconazole be that much more efficacious as hairloss treatments? We need to flesh this out.
Cheap antifungal drug (Itraconazole) may fight cancer: study
http://www.newsdaily.com/stories/tre63b ... ntifungal/
"Although it did not completely wipe out the tumors, the drug called itraconazole may boost the effects of other drugs, the researchers reported in the journal Cancer Cell.
Itraconazole is marketed under the brand name Sporanox by Johnson & Johnson subsidiary Janssen Pharmaceutica, mostly for treating a fungal infection called aspergillus.
The drug affects a so-called cascade of effects through a molecular pathway called Hedgehog, the researchers reported.
The researchers at Stanford University in California were looking for potential cancer drugs. They know that the Hedgehog pathway is involved in the development of cancer, so they looked for drugs that interfere with it."
Two cheap sources of itraconazole as Spazol/Sporanox/Itaspor...
http://www.alldaychemist.com/918-itaspor-100-mg-.html
http://www.drugstore4save.com/buy-Spazol.html
Fluconazole is also super-cheap.
I might just have to give this a shot.