- Reaction score
- 1,336
They make salt based powders to ship in summer because it'd more stable with heat. They may have left over stock to get rid of before making new batches.
Can anyone confirm if there is a huge difference between the two PGf2a molecules below? Wuhan says they only have
Prostaglandin F2α (tromethamine salt) in stock. I'm only seeing that the salt is more water soluble and has a heavier molecular weight.
https://www.caymanchem.com/product/16020/prostaglandin-f2α-(tromethamine-salt)
https://www.caymanchem.com/product/16010
What is the difference between the PGf2a @Analogies ordered, Latanoprost, and Bimatoprost? Do they all target the pgf2a angle? Pros/cons ?
What is the difference between the PGf2a @Analogies ordered, Latanoprost, and Bimatoprost? Do they all target the pgf2a angle? Pros/cons ?
useful reading thanks. States that cetirizine is a PGD2 inhibitor which I understand to be a different mechanism of action than something like latanoprost which works on PGF2A
ah good to know. I can see how powder would be much easier to work with in a topical than latanoprost goo. Is there any way to know how much weaker dinoprost or bimatoprost than latanoprost? Are they like 50% weaker or like or orders of magnitude?
It looks like the dinoprost @Analogies bought was about 40% cheaper than the latanoprost bought on a gram-for-gram basis. If it's only like 20% weaker and a powder form might go that route next time.
It should work on PGF2a also, even if it's not stated in the study. Unfortunately though, I haven't seen anyone able to replicate those results in the last 3 years with cetirizine on a monotherapy.
How exactly does ADC work? Do you need a prescription or anything, or is it just click and ship? Sorry for ignorance.ADC.
It's not even 20% weaker than latanoprost. Latanoprost is around 20% weaker than tafluprost ethyl amide, the gold standard for pgf2a agonism. Bimatoprost is significantly weaker than latanoprost, but dinoprost is comparable.
How exactly does ADC work? Do you need a prescription or anything, or is it just click and ship? Sorry for ignorance.
Why would cetirizine upregulate PGF2a? Am I missing something?
Estradiol or WAY-262611@pegasus2 what's your top pick for DKK-1 inhibition?
I updated the OP for everyone asking for more details.