HairClone will be available in some UK Clinics in "early 2022" - Paul Kemp, HairClone CEO

[pegasus2]

can we expect ome regrowth acording to him or is that only for maintenance? thanks sounds too good to be true

You'll almost certainly get some regrowth from it. I wouldn't hope for more than 1 norwood reversal at best, but to me that's pretty good without side effects. Their next version of the treatment is an attempt at full reversal, but it won't be available for several years, at least, if it's successful.

 

[Ralph Wiggum]

At this stage, if they haven't released any results, how can we have an idea of how much regrowth to expect?

 

[pegasus2]

At this stage, if they haven't released any results, how can we have an idea of how much regrowth to expect?

Because it's an improved version of this

Also, even Replicel got over 10% regrowth, and that's an inferior method.

 

[Rumspringa!]

They are using an early release program in the UK, basically they havnt completed the amount of trials to figure out best practice for the product. They are relying on the clinics to determine, number of injections/ how much in each injection/ depth of injections. Then they are going to aggregate the data and figure out the best practices. It is supposed to provide some regrowth yes, but there's not much data released yet.

 

[Super Metroid]

Because it's an improved version of thisView attachment 175548

Also, even Replicel got over 10% regrowth, and that's an inferior method.

If a treatment could guarantee maintenance and 10% regrowth, that would not be an inferior product, but the best solution possible.

 

[poopfeast420]

I talked to the head physician at Farjo clinic in England, he said it will likely take 3 treatments spread out over a couple years, the idea is that the cells from your hairs on the back of your head will migrate to the hair follicles in the top of your head close to injection sites and they will replicate and eventually develop the hair follicle into a follicle that is not succestiple to dht anymore. That is the theory.

Did he give you any sort of cost estimate?

 

[Joxy]

Is Claire Higgins still involve in this company? She is totally legit scientist and professor at Imperial College London (7th ranked worldwide).

 

[Joxy]

If a treatment could guarantee maintenance and 10% regrowth, that would not be an inferior product, but the best solution possible.

The best treatment is that who will stop hair loss at very early stage.

 

[Super Metroid]

You'll almost certainly get some regrowth from it. I wouldn't hope for more than 1 norwood reversal at best, but to me that's pretty good without side effects. Their next version of the treatment is an attempt at full reversal, but it won't be available for several years, at least, if it's successful.

How do you know this product will provide regrowth without side effects? As far as I know, they haven't published a study around it.

 

[pegasus2]

How do you know this product will provide regrowth without side effects? As far as I know, they haven't published a study around it.

Hair follicle neogenesis induced by cultured human scalp dermal papilla cells - PubMed

A process for the propagation of human DP cells has been developed that provides significant expansion of cells and maintenance of their hair-inductive capability, overcoming a major technical obstacle in the development of follicular cell implantation as a treatment for hair loss.

pubmed.ncbi.nlm.nih.gov

ClinicalTrials.gov

clinicaltrials.gov

Aderans reportedly had no side effects, same with Intercytex and Replicel.

 

[pegasus2]

The best treatment is that who will stop hair loss at very early stage.

Maybe for you. The best treatment for me is something that will reverse years of hair loss, turning the most miniaturized follicles into full, thick terminal hairs again. Dutasteride stops hair loss at the very early stage for the vast majority of men who take it

 

[LouisSarkozy]

Maybe for you. The best treatment for me is something that will reverse years of hair loss, turning the most miniaturized follicles into full, thick terminal hairs again. Dutasteride stops hair loss at the very early stage for the vast majority of men who take it

are you still hopefull for hmi to turn miniaturizezd vellus into terminal? thanks

 

[pegasus2]

are you still hopefull for hmi to turn miniaturizezd vellus into terminal? thanks

Yes.

 

[Super Metroid]

Hair follicle neogenesis induced by cultured human scalp dermal papilla cells - PubMed

A process for the propagation of human DP cells has been developed that provides significant expansion of cells and maintenance of their hair-inductive capability, overcoming a major technical obstacle in the development of follicular cell implantation as a treatment for hair loss.

pubmed.ncbi.nlm.nih.gov

ClinicalTrials.gov

clinicaltrials.gov

Aderans reportedly had no side effects, same with Intercytex and Replicel.

Self reported data from a decade ago.

The solutions of Intercytex / Adarans etc. were, for some reason, never commercially viable. So I doubt whether HairClone is doing the same as described in the papers you linked. They must have done something different and the question is whether the treatment is still safe en effective.

Another problem is also how reliable the science is, PRP also always great promise in studies, but in the real world, few people report a benefit from it.

 

[pegasus2]

Self reported data from a decade ago.

The solutions of Intercytex / Adarans etc. were, for some reason, never commercially viable. So I doubt whether HairClone is doing the same as described in the papers you linked. They must have done something different and the question is whether the treatment is still safe en effective.

Another problem is also how reliable the science is, PRP also always great promise in studies, but in the real world, few people report a benefit from it.

This is much better than prp. I don't know how Hairclone has improved on Aderans, but Aderans pulled funding from them during the financial crisis in order to focus on their profitable business. This was a time when almost everyone was risk averse, they had to protect their core business. Whatever they have done, you can be sure that they've only improved on it since the Aderans days

 

[Super Metroid]

This is much better than prp. I don't know how Hairclone has improved on Aderans, but Aderans pulled funding from them during the financial crisis in order to focus on their profitable business. This was a time when almost everyone was risk averse, they had to protect their core business. Whatever they have done, you can be sure that they've only improved on it since the Aderans days

It sounds possible, but given the amount of bs us hair loss sufferers have gone through, I will only believe it when I see it.

And of course, you don't take big risks in crisis times, but wouldn't the tech then be sold to a party that had the money to go to the market?

RepliCel / Shiseido is doing more or less the same thing I guess and haven't commercialized as well. And Shiseido is not lacking funds. I want you to be right but it doesn't completely add up yet to me.

 

[pegasus2]

It sounds possible, but given the amount of bs us hair loss sufferers have gone through, I will only believe it when I see it.

And of course, you don't take big risks in crisis times, but wouldn't the tech then be sold to a party that had the money to go to the market?

RepliCel / Shiseido is doing more or less the same thing I guess and haven't commercialized as well. And Shiseido is not lacking funds. I want you to be right but it doesn't completely add up yet to me.

Here's what Paul Kemp who was behind all these attempts had to say about it

2000. We raised a lot of VC money which enabled us to carry out the first cell therapy clinical trial about 10 years ago. I felt although it wasn’t a slam dunk, it did indicate what to do next but the VC investors wanted us to move onto something with shorter timelines and we sold the technology to Aderans where a similar thing happened. It is a feature of VC investment cycles is that they some of them aren’t in these things for the long term and they control the decisions. Intercytex was broken up in 2009 in the midst of the global financial crisis and I ran it for a few years in order to develop the last technology which was finally sold this year. The company has no employees and no facilities and your comment has made me realize that I do need to come to closure on that.

HairClone's CEO Dr. Paul Kemp Provides Feedback | Hair Loss Cure 2020

Paul Kemp of HairClone (UK) has given more details and feedback about the company's plans for its hair multiplication process. Mr. Kemp used to lead Intercytex.

www.hairlosscure2020.com

Replicel is different, they used DSC cells hoping those cells would repopulate the DP. Shiseido patented their own treatment similar to Hairclone's and then dumped Replicel. I think they only used Replicel for their experience and expertise in pursuing their own superior treatment. Rolf Buckler got played.

 

[Super Metroid]

Here's what Paul Kemp who was behind all these attempts had to say about it

HairClone's CEO Dr. Paul Kemp Provides Feedback | Hair Loss Cure 2020

Paul Kemp of HairClone (UK) has given more details and feedback about the company's plans for its hair multiplication process. Mr. Kemp used to lead Intercytex.

www.hairlosscure2020.com

Replicel is different, they used DSC cells hoping those cells would repopulate the DP. Shiseido patented their own treatment similar to Hairclone's and then dumped Replicel. I think they only used Replicel for their experience and expertise in pursuing their own superior treatment. Rolf Buckler got played.

Fair enough.

Anyway, there are a few companies moving in the "sideless maintenance, some regrowth" market. Logic would dictate that other parties shouldn't wait too long with commercializing a product until someone claims the market before them. Let's say HairClone indeed releases a product to the market in the coming months and delivering on safety and efficacy, that should be a big crush for Shiseido. They might hope to release a slightly better or cheaper option, but the profits would never be the same compared to the situation in which they would have a monopoly on such a product.

Would you agree with that assessment?

 

[Micky_007]

Self reported data from a decade ago.

The solutions of Intercytex / Adarans etc. were, for some reason, never commercially viable. So I doubt whether HairClone is doing the same as described in the papers you linked. They must have done something different and the question is whether the treatment is still safe en effective.

Another problem is also how reliable the science is, PRP also always great promise in studies, but in the real world, few people report a benefit from it.

Yes, also, we can't just base the efficacy of a treatment based on prior attempts from a company. Take Histogen for example, on their second attempt their results were worse than their initial

 

[pegasus2]

Fair enough.

Anyway, there are a few companies moving in the "sideless maintenance, some regrowth" market. Logic would dictate that other parties shouldn't wait too long with commercializing a product until someone claims the market before them. Let's say HairClone indeed releases a product to the market in the coming months and delivering on safety and efficacy, that should be a big crush for Shiseido. They might hope to release a slightly better or cheaper option, but the profits would never be the same compared to the situation in which they would have a monopoly on such a product.

Would you agree with that assessment?

Different markets, but I don't think Shiseido will move forward unless they believe they can virtually cure hair loss. It's too late at this point with all the other companies moving towards clinical trials.